Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brett Fields"'
Autor:
The sbv IMPROVER project team (in alphabetical order), Stephanie Boue, Brett Fields, Julia Hoeng, Jennifer Park, Manuel C. Peitsch, Walter K. Schlage, Marja Talikka, The Challenge Best Performers (in alphabetical order), Ilona Binenbaum, Vladimir Bondarenko, Oleg V. Bulgakov, Vera Cherkasova, Norberto Diaz-Diaz, Larisa Fedorova, Svetlana Guryanova, Julia Guzova, Galina Igorevna Koroleva, Elena Kozhemyakina, Rahul Kumar, Noa Lavid, Qingxian Lu, Swapna Menon, Yael Ouliel, Samantha C. Peterson, Alexander Prokhorov, Edward Sanders, Sarah Schrier, Golan Schwaitzer Neta, Irina Shvydchenko, Aravind Tallam, Gema Villa-Fombuena, John Wu, Ilya Yudkevich, Mariya Zelikman
Publikováno v:
F1000Research, Vol 4 (2015)
The construction and application of biological network models is an approach that offers a holistic way to understand biological processes involved in disease. Chronic obstructive pulmonary disease (COPD) is a progressive inflammatory disease of the
Externí odkaz:
https://doaj.org/article/5fa7faaeff274b1bb1cc7eeae79d3bbf
Autor:
Marja Talikka, Julia Hoeng, Karsta Luettich, Justyna Szostak, Manuel C. Peitsch, Brett Fields, Jennifer Park, Vered Katz Ben-Yair, Anita R. Iskandar, Ulrike Kogel, Shay Rotkopf, Yang Xiang, Walter K. Schlage
Publikováno v:
Cancer Research. 75:B1-19
Over the past few years, we constructed a number of biological network models representing comprehensive connectivity maps of fundamental molecular mechanisms regulating cell proliferation, cellular stress, and cell fate in the healthy and inflamed l
Autor:
Emmanuel Guedj, Natalia Boukharov, Maciej Cabanski, Carine Poussin, Nikolai V. Ivanov, Manuel C. Peitsch, Anita R. Iskandar, Stéphanie Boué, Julia Hoeng, Brett Fields, Walter K. Schlage, Michael J. Peck, Natalie Dror, Marcel Geertz, Celine Merg, Ulrike Kogel, Marja Talikka, Hector DeLeon
Publikováno v:
Inflammation Research
Background Mouse models are useful for studying cigarette smoke (CS)-induced chronic pulmonary pathologies such as lung emphysema. To enhance translation of large-scale omics data from mechanistic studies into pathophysiological changes, we have deve
Autor:
William Hayes, Jurjen W. Westra, Stéphanie Boué, Alain Sewer, Emilija Veljkovic, Julia Hoeng, Brett Fields, Manuel C. Peitsch, Sam Ansari, Jennifer Park, Renee Deehan Kenney, Marja Talikka, Florian Martin, Anselmo Di Fabio, Walter K. Schlage
Publikováno v:
Database: The Journal of Biological Databases and Curation
With the wealth of publications and data available, powerful and transparent computational approaches are required to represent measured data and scientific knowledge in a computable and searchable format. We developed a set of biological network mod
Autor:
Katherine B. Hubbard, T. J. Murphy, Kimberly Gernert, Kaiming Xu, R. Brett Fields, Richard D. Peavy, Anthony G. Lau, Terri T. Lee, C. Justin Lee, John R. Hepler
Publikováno v:
Molecular Pharmacology. 67:2102-2114
Gqalpha family members (Gqalpha, G11alpha, G14alpha, and G15/16alpha) stimulate phospholipase Cbeta (PLCbeta) and inositol lipid signaling but differ markedly in amino acid sequence and tissue distribution predicting unappreciated functional diversit
Autor:
Richard D, Peavy, Katherine B, Hubbard, Anthony, Lau, R Brett, Fields, Kaiming, Xu, C Justin, Lee, Terri T, Lee, Kimberly, Gernert, T J, Murphy, John R, Hepler
Publikováno v:
Molecular pharmacology. 67(6)
Gqalpha family members (Gqalpha, G11alpha, G14alpha, and G15/16alpha) stimulate phospholipase Cbeta (PLCbeta) and inositol lipid signaling but differ markedly in amino acid sequence and tissue distribution predicting unappreciated functional diversit
Autor:
Carine Poussin, Michael J. Peck, Stephan Gebel, Marja Talikka, Aaron VanHooser, R. Brett Fields, Carole Mathis, Natalia Boukharov, Manuel C. Peitsch, Walter K. Schlage, Julia Hoeng, Jurjen W. Westra, Renée Deehan, Katrin Stolle, Stéphanie Boué, Emilija Veljkovic, Hector De Leon, Vy Hoang
Publikováno v:
Journal of Translational Medicine
Background Numerous inflammation-related pathways have been shown to play important roles in atherogenesis. Rapid and efficient assessment of the relative influence of each of those pathways is a challenge in the era of “omics” data generation. T