Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Brett D. Shepard"'
Autor:
Brett D Shepard, Davide De Forni, David R McNamara, Andrea Foli, Stacey A Rizza, Roshini S Abraham, Keith Knutson, Peter J Wettstein, Franco Lori, Andrew D Badley
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3096 (2008)
During uncontrolled HIV disease, both TNF-related apoptosis inducing ligand (TRAIL) and TRAIL receptor expression are increased. Enhanced TRAIL sensitivity is due to TRAIL receptor up-regulation induced by gp120. As a result of successful antiretrovi
Externí odkaz:
https://doaj.org/article/7c716647a9ab4942bd2923f33ba0cdf0
Autor:
Amy M. Sainski, Gary D. Bren, Scott H. Kaufmann, David J. Schnepple, Sergey Trushin, Sekar Natesampillai, Brett D. Shepard, Alicia Algeciras-Schimnich, Xue W. Meng, Stacey A. Rizza, Nathan W. Cummins, Andrew D. Badley
Publikováno v:
Journal of Biological Chemistry. 286:35742-35754
Virus-host interactions are characterized by the selection of adaptive mechanisms by which to evade pathogenic and defense mechanisms, respectively. In primary T cells infected with HIV, HIV infection up-regulates TNF-related apoptosis inducing ligan
Autor:
Brett D. Shepard, Andrew D. Badley
Publikováno v:
Anti-Infective Agents in Medicinal Chemistry. 8:87-101
TNF-related apoptosis inducing ligand (TRAIL) is a key mediator of the innate immune response to infection. While TRAIL-mediated apoptosis plays an essential role in the clearance of virus-infected cells, its physiologic role also includes immunosurv
Publikováno v:
Journal of Bacteriology. 185:4393-4401
Enterococcus faecalis has emerged as a leading cause of nosocomial bacteremia, surgical site infection, and urinary tract infection (29). The development of multiple antibiotic resistances in enterococci in recent years compromises existing therapies
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 3, p e4875 (2009)
PLoS ONE, Vol 4, Iss 3, p e4875 (2009)
BACKGROUND HIV envelope glycoprotein gp120 causes cellular activation resulting in anergy, apoptosis, proinflammatory cytokine production, and through an unknown mechanism, enhanced HIV replication. METHODOLOGY/PRINCIPAL FINDINGS We describe that the
Autor:
Michael S. Gilmore, Brett D. Shepard
Enterococci rank among leading causes of nosocomial bacteremia and urinary tract infection and are also a leading cause of community acquired subacute endocarditis. Limited evidence suggests that biological cues in serum and urine may play an importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b61bc54348c64616abbaeee2260058b
https://europepmc.org/articles/PMC128128/
https://europepmc.org/articles/PMC128128/
Autor:
Michael S. Gilmore, Brett D. Shepard
Publikováno v:
Microbes and infection. 4(2)
Enterococci possess a vast array of mechanisms to resist the lethal effects of most antimicrobial drugs currently approved for therapeutic use in humans, thus presenting a considerable therapeutic challenge. This review summarizes current concepts re
Autor:
Michael S. Gilmore, Brett D. Shepard
Publikováno v:
Applied and environmental microbiology. 65(4)
Enterococci have emerged among the leading causes of nosocomial infection. With the goal of analyzing enterococcal genes differentially expressed in environments related to commensal or environmental colonization and infection sites, we adapted and o
Autor:
Michael S. Gilmore, Brett D. Shepard
Publikováno v:
Streptococci and the Host ISBN: 9781489918277
Enterococcal bacteremia and other important clinical sequelae are associated with significant morbidity and mortality, particularly among hospitalized and immunocompromised patients4. In recent years, enterococci have emerged among the leading causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92d217f5184b223cca4511ec5e0d8361
https://doi.org/10.1007/978-1-4899-1825-3_183
https://doi.org/10.1007/978-1-4899-1825-3_183