Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Brett D. Dufour"'
Autor:
Tiffany Hong, Erin McBride, Brett D. Dufour, Carmen Falcone, Mai Doan, Stephen G. Noctor, Verónica Martínez-Cerdeño
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Chandelier (Ch) cells are cortical interneurons with axon terminal structures known as cartridges that synapse on the axon initial segment of excitatory pyramidal neurons. Previous studies indicate that the number of Ch cells is decreased in autism,
Externí odkaz:
https://doaj.org/article/e24ed4b9a24f4d38bac2ac1f3be21808
Autor:
Brett D. Dufour, Jodi L. McBride
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 214-229 (2019)
Huntington's disease (HD) is a fatal genetic neurological disorder caused by a mutation in the human Huntingtin (HTT) gene. This mutation confers a toxic gain of function of the encoded mutant huntingtin (mHTT) protein, leading to widespread neuropat
Externí odkaz:
https://doaj.org/article/eb4e401d0d994ef5a54d5d54c298aad2
Publikováno v:
Autism. :136236132311540
Autism spectrum disorder is a neurodevelopmental condition characterized by deficits in social communication and repetitive behaviors. How specific anatomical alterations contribute to the clinical profile of autism spectrum disorder remains largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c073b73aa5134efa472d347d20a6914a
https://doi.org/10.1177/13623613231154053
https://doi.org/10.1177/13623613231154053
Autor:
Efraín Buriticá, Lilia Albores-Gallo, Patrick R. Hof, Mar Pacheco-Herrero, Wilmar Saldarriaga, Carla A. Mazefsky, Manuel F. Casanova, Verónica Martínez-Cerdeño, Brett D. Dufour, Randi J Hagerman, Eric London, Ana Yris Silvestre-Sosa, Holly Zajac Gastgeb, Paul J. Hagerman, Amaya Miquelajauregui, Julia Kofler, José Luna-Muñoz
Publikováno v:
Brain pathology (Zurich, Switzerland), vol 32, iss 2
Neurodevelopmental disorders (NDDs) are conditions that present with brain dysfunction due to alterations in the processes of brain development. They present with neuropsychiatric, cognitive, and motor symptoms. Autism spectrum disorder (ASD) and Fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9052b451b9627dc60adf9acc1b713661
https://escholarship.org/uc/item/2dj3m45q
https://escholarship.org/uc/item/2dj3m45q
Autor:
Stephen C. Noctor, Verónica Martínez-Cerdeño, Sarwat Amina, Rosalia Perez Castro, Carmen Falcone, Weston Pearson, Jade Regalado, Tiffany Hong, Brett D. Dufour
Publikováno v:
Neuroscience. 437:76-86
Some forms of Autism Spectrum Disorder, a neurodevelopmental syndrome characterized by impaired communication and social skills as well as repetitive behaviors, are purportedly associated with dysregulation of the excitation/inhibition balance in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fd46dc11296517c3ab371bd26521c0e
https://doi.org/10.1016/j.neuroscience.2020.04.025
https://doi.org/10.1016/j.neuroscience.2020.04.025
Autor:
Stephen C. Noctor, Tiffany Hong, Xiaohui Chen, Carmen Falcone, Natalie Ya Mevises, Brett D. Dufour, Verónica Martínez Cerdeño
Publikováno v:
Autism
Autism spectrum disorder is a neurodevelopmental condition characterized by impaired social communication and repetitive behaviors. Changes in the number of specific cell types in the cerebral cortex could produce a dramatic alteration in the regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a621ffe2b5c78ff09bdf2ef0b5214b
https://pubmed.ncbi.nlm.nih.gov/34107793
https://pubmed.ncbi.nlm.nih.gov/34107793
Repeated cycles of alcohol intoxication and withdrawal both induce profound changes in gene expression that can contribute to the physiological and behavioral consequences of ethanol. Since neuroinflammation is an important consequence of these chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8537e937183b230e6d5332c3b9bdd7a5
https://doi.org/10.1101/2020.09.02.280156
https://doi.org/10.1101/2020.09.02.280156
Autor:
Yingratana A. McLennan, Verónica Martínez-Cerdeño, Maria Jimena Salcedo-Arellano, Brett D. Dufour, Randi J Hagerman
Publikováno v:
Neurobiology of disease, vol 136
Neurobiology of Disease, Vol 136, Iss, Pp 104740-(2020)
Neurobiology of Disease, Vol 136, Iss, Pp 104740-(2020)
This review aims to assemble many years of research and clinical experience in the fields of neurodevelopment and neuroscience to present an up-to-date understanding of the clinical presentation, molecular and brain pathology associated with Fragile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2095f527037e20c4529fc4ec8bc0418c
https://pubmed.ncbi.nlm.nih.gov/31927143
https://pubmed.ncbi.nlm.nih.gov/31927143
Autor:
Dana Button, Yun Wang, William A. Liguore, Brett D. Dufour, Jacqueline S. Domire, Sathya Srinivasan, Jodi L. McBride
Publikováno v:
Mol Ther
The ability of recombinant adeno-associated virus (AAV) to deliver transgenes to the CNS has allowed for several advancements in the field of gene therapy to treat brain disorders. Although most AAVs do not readily cross the blood-brain barrier and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9428eceb0925212000ffa9b0d0e3c84e
https://pubmed.ncbi.nlm.nih.gov/31420242
https://pubmed.ncbi.nlm.nih.gov/31420242
Autor:
Brett D. Dufour, Jodi L. McBride
Publikováno v:
Experimental Neurology. 283:308-317
Huntington's disease (HD) is a genetic neurological disorder that causes severe and progressive motor, cognitive, psychiatric, and metabolic symptoms. There is a robust, significant elevation in circulating levels of the stress hormone, cortisol, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def068e36d44cb4fd136a81f539c8191
https://doi.org/10.1016/j.expneurol.2016.06.028
https://doi.org/10.1016/j.expneurol.2016.06.028