Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Brett D, Keiper"'
Autor:
Hayden P. Huggins, Brett D. Keiper
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Translational regulation of mRNAs is critically important for proper gene expression in germ cells, gametes, and embryos. The ability of the nucleus to control gene expression in these systems may be limited due to spatial or temporal constraints, as
Externí odkaz:
https://doaj.org/article/5314af0ef6164ea0aec24b3a734365c2
Autor:
Jesse D. Rochester, Hyemin Min, Gita A. Gajjar, Catherine S. Sharp, Nathaniel J. Maki, Jarod A. Rollins, Brett D. Keiper, Joel H. Graber, Dustin L. Updike
Publikováno v:
Dev Biol
Germ granules harbor processes that maintain germline integrity and germline stem cell capacity. Depleting core germ granule components in C. elegans leads to the reprogramming of germ cells, causing them to express markers of somatic differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0843dbe3a41467795fe337df1e8c9d7b
https://doi.org/10.1016/j.ydbio.2022.10.003
https://doi.org/10.1016/j.ydbio.2022.10.003
Autor:
Brett D. Keiper, Hayden P. Huggins
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Translational regulation of mRNAs is critically important for proper gene expression in germ cells, gametes, and embryos. The ability of the nucleus to control gene expression in these systems may be limited due to spatial or temporal constraints, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc5abb823fc3190e4428baa85dc147b
https://www.frontiersin.org/article/10.3389/fcell.2020.00562/full
https://www.frontiersin.org/article/10.3389/fcell.2020.00562/full
Autor:
Melissa A. Henderson, Hayden P. Huggins, David S. Buckner, Peter R. Boag, Madhu S. Sengupta, Jenna L. Hoffman, Myon-Hee Lee, Brett D. Keiper, Hamilton J. Stoffel, Jacob S. Subash
Publikováno v:
Journal of Cell Science.
Germ cells use both positive and negative mRNA translational control to regulate gene expression that drives their differentiation into gametes. mRNA translational control is mediated by RNA-binding proteins, miRNAs, and translation initiation factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc751f2652d45f62fb2ca35fd642bbd5
https://doi.org/10.1242/jcs.237990
https://doi.org/10.1242/jcs.237990
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24444 (2011)
Apoptosis is a natural process during animal development for the programmed removal of superfluous cells. During apoptosis general protein synthesis is reduced, but the synthesis of cell death proteins is enhanced. Selective translation has been attr
Externí odkaz:
https://doaj.org/article/fb45cd05d35a45e59f8f627adb6b98b7
Autor:
Hayden P, Huggins, Jacob S, Subash, Hamilton, Stoffel, Melissa A, Henderson, Jenna L, Hoffman, David S, Buckner, Madhu S, Sengupta, Peter R, Boag, Myon-Hee, Lee, Brett D, Keiper
Publikováno v:
J Cell Sci
Germ cells use both positive and negative mRNA translational control to regulate gene expression that drives their differentiation into gametes. mRNA translational control is mediated by RNA-binding proteins, miRNAs and translation initiation factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63139d10d8515b7cdb312df4131fb964
https://pubmed.ncbi.nlm.nih.gov/32079657
https://pubmed.ncbi.nlm.nih.gov/32079657
Autor:
Brett D. Keiper
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 1, p 173 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 1, p 173 (2019)
Cellular mRNAs in plants and animals have a 5′-cap structure that is accepted as the recognition point to initiate translation by ribosomes. Consequently, it was long assumed that the translation initiation apparatus was built solely for a cap-depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d551e463f495c2353ddda4cda54a739
http://europepmc.org/articles/PMC6337596
http://europepmc.org/articles/PMC6337596
Autor:
Guillaume Jannot, Edlyn Wu, James A. Wohlschlegel, Martin J. Simard, Mathieu N. Flamand, Brett D. Keiper, Thomas F. Duchaine, Ajay A. Vashisht
Publikováno v:
Nucleic Acids Research
Cytoplasmic poly(A)-binding proteins (PABPs) link mRNA 3′ termini to translation initiation factors, but they also play key roles in mRNA regulation and decay. Reports from mice, zebrafish and Drosophila further involved PABPs in microRNA (miRNA)-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbc7fe848e894b069ab1a310aa0ba43
https://doi.org/10.1093/nar/gkw276
https://doi.org/10.1093/nar/gkw276
Autor:
Christopher B. Geyer, Ellen K. Velte, Bryan A. Niedenberger, Jonathan T. Busada, Brett D. Keiper
Publikováno v:
Developmental Biology. 407(1):90-102
Spermatogonial stem cells (SSCs) must balance self-renewal with production of transit-amplifying progenitors that differentiate in response to retinoic acid (RA) before entering meiosis. This self-renewal vs. differentiation spermatogonial fate decis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6dffc7284b04dca016717d4cad6078
Autor:
Andrew J. Friday, Brett D. Keiper
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2015 (2015)
BioMed Research International, Vol 2015 (2015)
Ultimately, the production of new proteins in undetermined cells pushes them to new fates. Other proteins hold a stem cell in a mode of self-renewal. In germ cells, these decision-making proteins are produced largely from translational control of pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd34716a4d843c26f37e5037a5b1058
https://doi.org/10.1155/2015/327963
https://doi.org/10.1155/2015/327963