Peripheral vestibular system: Age-related vestibular loss and associated deficits

Autor: Tatjana Rundek, Xue Zhong Liu, Brett Colbert, Bonnie E. Levin, David A. Loewenstein, Jennifer Coto, Michael E. Hoffer, David J. Lee, Carmen L. Alvarez, Joshua Huppert, Carey D. Balaban, Susan H. Blanton, Ivette Cejas

Publikováno v: Journal of Otology, Vol 16, Iss 4, Pp 258-265 (2021)
Journal of Otology

Given the interdependence of multiple factors in age-related vestibular loss (e.g., balance, vision, cognition), it is important to examine the individual contributions of these factors with ARVL. While the relationship between the vestibular and vis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50e92189db8102e9d07170e7cfe3e55
http://www.sciencedirect.com/science/article/pii/S1672293021000271

Stem Cells and Gene Therapy in Progressive Hearing Loss: the State of the Art

Autor: Karl R. Koehler, Aida Nourbakhsh, Aziz El-Amraoui, Xue Zhong Liu, Eric Nisenbaum, Brett Colbert, Derek M. Dykxhoorn, Zheng-Yi Chen

Publikováno v: Journal of the Association for Research in Otolaryngology
Journal of the Association for Research in Otolaryngology, 2021, 22 (2), pp.95-105. ⟨10.1007/s10162-020-00781-0⟩
JARO: Journal of the Association for Research in Otolaryngology
Journal of the Association for Research in Otolaryngology, Springer Verlag, 2021, 22 (2), pp.95-105. ⟨10.1007/s10162-020-00781-0⟩

Progressive non-syndromic sensorineural hearing loss (PNSHL) is the most common cause of sensory impairment, affecting more than a third of individuals over the age of 65. PNSHL includes noise-induced hearing loss (NIHL) and inherited forms of deafne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbf5fc979b5871545629db8f741d705
https://hal.sorbonne-universite.fr/hal-03125733

Long-range cis-regulatory elements controlling GDF6 expression are essential for ear development

Autor: Cynthia C. Morton, Mustafa Tekin, Emine Ikbal Atli, Shengru Guo, Hakan Gurkan, Suat Fitoz, Clemer Abad, Claire J. Sineni, Selma Demir, Brett Colbert, Gozde Cosar Seyhan, Duygu Duman, Nicholas C. Gosstola, Derek M. Dykxhoorn, Serhat Seyhan, Guney Bademci, Filiz Basak Cengiz, Katherina Walz, Armagan Incesulu

Publikováno v: J Clin Invest
Bademci, G, Abad, C, Cengiz, F B, Seyhan, S, Incesulu, A, Guo, S, Fitoz, S, Atli, E I, Gosstola, N C, Demir, S, Colbert, B M, Seyhan, G C, Sineni, C J, Duman, D, Gurkan, H, Morton, C C, Dykxhoorn, D M, Walz, K & Tekin, M 2020, ' Long-range cis-regulatory elements controlling GDF6 expression are essential for ear development ', Journal of Clinical Investigation . https://doi.org/10.1172/JCI136951

Molecular mechanisms governing the development of the mammalian cochlea, the hearing organ, remain largely unknown. Through genome sequencing in 3 subjects from 2 families with nonsyndromic cochlear aplasia, we identified homozygous 221-kb and 338-kb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0204a08598dce142d8000a9e816736c
https://pubmed.ncbi.nlm.nih.gov/32369452

P372 Bacterial vaginosis and high-risk human papillomavirus coinfection among african american women in the united states

Autor: Kalai Mathee, Hansi Kumari, Giri Narasimhan, Daniel Ruiz-Perez, Karl Krupp, Brett Colbert, Purnima Madhivanan, Makella Coudray

Publikováno v: Poster Presentations.

Background Bacterial vaginosis (BV) increases the risk of many sexually transmitted infections. The co-occurrence of persistent BV and high-risk HPV (HrHPV) increases the risk of developing cervical cancer. This study aims to investigate the co-occur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d9886f17daf04e89b073a389358ea3c
https://doi.org/10.1136/sextrans-2019-sti.474

Alginate-regulating genes are identified in the clinical cystic fibrosis isolate of Pseudomonas aeruginosa PA2192

Autor: Kalai Mathee, Brett Colbert, Sundar Pandey, Hansi Kumari, Ana Pinon, Lior Frey

Cystic fibrosis (CF) is a genetic disorder that leads to a buildup of mucus in the lungs ideal for bacterial colonization. WhenPseudomonas aeruginosaenters the CF lung, it undergoes a conversion from nonmucoid to mucoid; colonization by a mucoid stra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c3ac58b8fcd60735ec676ef0a3c0c9