Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Brett A. Shook"'
Autor:
Satish kumar Reddy Noonepalle, Maria Gracia-Hernandez, Nima Aghdam, Michael Berrigan, Hawa Coulibaly, Xintang Li, Christian Zevallos-Delgado, Andrew Pletcher, Bryan Weselman, Erica Palmer, Tessa Knox, Eduardo Sotomayor, Katherine B. Chiappinelli, Duncan Wardrop, Anelia Horvath, Brett A. Shook, Norman Lee, Anatoly Dritschilo, Rohan Fernandes, Karthik Musunuri, Maho Shibata, Alejandro Villagra
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract Background Macrophage-based cell therapies have shown modest success in clinical trials, which can be attributed to their phenotypic plasticity, where transplanted macrophages get reprogrammed towards a pro-tumor phenotype. In most tumor typ
Externí odkaz:
https://doaj.org/article/23fe4a7dd71744ae838f9d49bd7f4b13
Autor:
Paula O. Cooper, Sarah S. Kleb, Satish K. Noonepalle, Veronica M. Amuso, Rohan Varshney, Michael C. Rudolph, Tanvir K. Dhaliwal, Darlene V. Nguyen, Miguel F. Mazumder, Najuma S. Babirye, Ruchi Gupta, Bao-Ngoc Nguyen, Brett A. Shook
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114288- (2024)
Summary: Lipids have emerged as potent regulators of immune cell function. In the skin, adipocyte lipolysis increases the local pool of free fatty acids and is essential for coordinating early macrophage inflammation following injury. Here, we invest
Externí odkaz:
https://doaj.org/article/1fe22ae4fe064e07b1147b35c748ad01
Autor:
Rachel K. Zwick, Michael C. Rudolph, Brett A. Shook, Brandon Holtrup, Eve Roth, Vivian Lei, Alexandra Van Keymeulen, Victoria Seewaldt, Stephanie Kwei, John Wysolmerski, Matthew S. Rodeheffer, Valerie Horsley
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
During mammary gland involution, the organ undergoes extensive remodeling. Here, the authors explore the role of mammary gland adipose tissue (mgWAT) in this process and demonstrate that adipocyte hypertrophy and lipid trafficking underlie mgWAT expa
Externí odkaz:
https://doaj.org/article/6df449e761d24bb9b6a16a56627b5f82
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1752 (2021)
Diabetic wound healing is associated with impaired function and reduced numbers of myofibroblasts, a heterogeneous cell population with varying capacities to promote repair. To determine how diabetes alters myofibroblast composition, we performed flo
Externí odkaz:
https://doaj.org/article/e1e3abcad76b4ba1884f1663cf501ef3
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1933 (2021)
Irregular inflammatory responses are a major contributor to tissue dysfunction and inefficient repair. Skin has proven to be a powerful model to study mechanisms that regulate inflammation. In particular, skin wound healing is dependent on a rapid, r
Externí odkaz:
https://doaj.org/article/60a2f28b3fff4f949131b272b0084bff
Autor:
Satish Kumar Reddy Noonepalle, Maria Gracia Hernandez, Christian Zevallos Delgado, Nima Aghdam, Nithya Gajendran, Tessa Knox, Karen Tan, Eduardo Sotomayor, Katherine B. Chiappinelli, Duncan Wardrop, Anelia Horvath, Brett A. Shook, Norman Lee, Anatoly Dritschilo, Rohan Fernandes, Maho Shibata, Karthik Musunuri, Alejandro Villagra
Publikováno v:
Cancer Research. 83:900-900
Tumor-associated macrophages (TAMs) play a critical role in shaping the tumor microenvironment (TME). Responding to numerous cues from various cell types present in the tumor, TAMs often exhibit a spectrum of phenotypes, often ranging between M1 (inf
Publikováno v:
Biomedicines; Volume 9; Issue 12; Pages: 1752
Biomedicines, Vol 9, Iss 1752, p 1752 (2021)
Biomedicines
Biomedicines, Vol 9, Iss 1752, p 1752 (2021)
Biomedicines
Diabetic wound healing is associated with impaired function and reduced numbers of myofibroblasts, a heterogeneous cell population with varying capacities to promote repair. To determine how diabetes alters myofibroblast composition, we performed flo
Publikováno v:
Cell Stem Cell
Cell Stem Cell, 28(3), 367-369. Cell Press
Cell Stem Cell, 28(3), 367-369. Cell Press
COVID-19 has unfortunately halted lab work, conferences, and in-person networking, which is especially detrimental to researchers just starting their labs. Through social media and our reviewer networks, we met some early-career stem cell investigato
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1933, p 1933 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Irregular inflammatory responses are a major contributor to tissue dysfunction and inefficient repair. Skin has proven to be a powerful model to study mechanisms that regulate inflammation. In particular, skin wound healing is dependent on a rapid, r
Autor:
Valerie Horsley, Kathryn Miller-Jensen, Brett A. Shook, Henry C. Hsia, Emilio Salazar-Gatzimas, Vivian Lei, Biraja C. Dash, Guillermo C. Rivera-Gonzalez, Andrés R. Muñoz-Rojas, Rachel K. Zwick, Renee R. Wasko, Francesc López-Giráldez, Krystal D. Aultman, Damon A. Clark, Jack L. Arbiser
INTRODUCTION Fibroblasts produce extracellular matrix (ECM) molecules that regulate tissue strength and resilience. Imbalanced ECM maintenance leads to tissue dysfunction. Although multiple populations of fibroblasts support uninjured skin function,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59acb3ba2add39851f7febdcab60158
https://europepmc.org/articles/PMC6684198/
https://europepmc.org/articles/PMC6684198/