Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Brett A. Leav"'
Autor:
Trevor J Morin, Teresa J Broering, Brett A Leav, Barbra M Blair, Kirk J Rowley, Elisabeth N Boucher, Yang Wang, Peter S Cheslock, Michael Knauber, David B Olsen, Steve W Ludmerer, Gyongyi Szabo, Robert W Finberg, Robert H Purcell, Robert E Lanford, Donna M Ambrosino, Deborah C Molrine, Gregory J Babcock
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002895 (2012)
Hepatitis C virus (HCV) infection is a leading cause of liver transplantation and there is an urgent need to develop therapies to reduce rates of HCV infection of transplanted livers. Approved therapeutics for HCV are poorly tolerated and are of limi
Externí odkaz:
https://doaj.org/article/8744314b7609471e91dbe560c056d0b8
Autor:
Kathleen A. Rogers, Shizuo Akira, Brett A. Leav, Arlin B. Rogers, Ana M. Sanchez, Edouard Vannier, Honorine D. Ward, Douglas T. Golenbock, Satoshi Uematsu
Publikováno v:
Infection and Immunity. 74:549-556
Cryptosporidiumspp. cause diarrheal disease worldwide. Innate immune responses mediating resistance to this parasite are not completely understood. To determine whether MyD88-dependent pathways play a role in resistance toCryptosporidium parvum, we c
Autor:
S P Cohen, Richard S. Blumberg, Brett A. Leav, Honorine D. Ward, Nihal T. Godiwala, Masaru Yoshida, Kathleen A. Rogers
Publikováno v:
Infection and Immunity. 73:8425-8428
Resistance to and control of Cryptosporidium parvum infection in mice in the absence of adaptive immunity appears to be gamma interferon (IFN-γ) dependent. Using an IFN-γ-neutralizing antibody in a murine model, we demonstrated increased susceptibi
Publikováno v:
Clinical Infectious Diseases. 36:903-908
Cryptosporidium species are protozoan parasites that cause mainly enteric illnesses in humans and other animals. The mode of transmission is most commonly waterborne, but other sources of infection, including foodborne and person-to-person spread, ha
Autor:
Zejia Yang, Matthew J. C. Ellis, Brett A. Leav, Audrey Rasmussen, Kevin J. Cullen, James A. Zweibel, Amelia Pearce, Marc E. Lippman
Publikováno v:
Molecular Endocrinology. 10:286-297
We have investigated the autocrine regulation of insulin-like growth factor-II (IGF-II) signaling by the insulin-like growth factor-I receptor (IGF-IR) and the insulin-like growth factor-II/mannose 6-phosphate receptor (IGF-IIR) in MCF-7 breast cance
Publikováno v:
Applied and environmental microbiology. 72(6)
Established methods for quantifying experimental Cryptosporidium infection are highly variable and subjective. We describe a new technique using quantitative real-time PCR (qPCR) that can be used to measure in vitro and in vivo laboratory infections
Autor:
Richard G. Nelson, Michael L. Bennish, Brett A. Leav, Roberta M. O' Connor, Nigel C. Rollins, Ana María Cevallos, Malanie R. Mackay, Akudo Anyanwu, Honorine D. Ward, Gurpreet Kindra
Publikováno v:
Infection and immunity. 70(7)
Cryptosporidium sp. is a significant cause of diarrheal disease, particularly in human immunodeficiency virus (HIV)-infected patients in developing countries. We recently cloned and sequenced several alleles of the highly polymorphic single-copy Cryp
Publikováno v:
New England Journal of Medicine. 343:586-586
To the Editor: A 44-year-old man with moderately severe asthma was first seen in the infectious-disease clinic in November 1999 because of a recent diagnosis of pulmonary aspergillosis. The patient had noted an increase in his asthma symptoms during