Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Brett A. Cromer"'
Autor:
Alexandru Zabara, Josephine Tse Yin Chong, Isabelle Martiel, Laura Stark, Brett A. Cromer, Chiara Speziale, Calum John Drummond, Raffaele Mezzenga
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
In meso crystallization of membrane proteins is limited to proteins with small extracellular domains (ECDs). Here, authors combine monoacylglycerols and phospholipids to design stable ultra-swollen bicontinuous cubic phases that allow in meso crystal
Externí odkaz:
https://doaj.org/article/8cca585f27924bc6bba1d6ae8151e364
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 4, Iss 3, Pp 244-255 (2014)
Pharmacological targeting of glutamate-gated chloride channels (GluCls) is a potent anthelmintic strategy, evidenced by macrocyclic lactones that eliminate numerous roundworm infections by activating roundworm GluCls. Given the recent identification
Externí odkaz:
https://doaj.org/article/30f30a81451244ecac85f206df66637d
Publikováno v:
Stem Cells International, Vol 2020 (2020)
With an increasing focus on the large-scale expansion of mesenchymal stem cells (MSCs) required for clinical applications for the treatment of joint and bone diseases such as osteoarthritis, the optimisation of conditions for in vitro MSC expansion r
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2020 (2020)
Stem Cells International, Vol 2020 (2020)
Extracellular vesicles (EVs) are cell-derived membrane-bound nanoparticles, which act as shuttles, delivering a range of biomolecules to diverse target cells. They play an important role in maintenance of biophysiological homeostasis and cellular, ph
Autor:
Thomas P. Gunnarsson, Martin Thomassen, Jens Bangsbo, Casper Skovgaard, Peter M. Christensen, Morten Hostrup, Brett A. Cromer, Robyn M. Murphy
Publikováno v:
Journal of Applied Physiology. 125:470-478
Cl−channel protein 1 (ClC-1) may be important for excitability and contractility in skeletal muscle, but ClC-1 abundance has not been examined in human muscle. The aim of the present study was to examine ClC-1 abundance in human skeletal muscle, in
Publikováno v:
Current molecular medicine. 21(1)
Pluripotent stem cells (PSCs) are powerful tools for studying developmental biology and neuronal diseases. Conventional differentiation protocols require several intermediate states and different culture conditions, inefficiently generating mixed sub
Publikováno v:
Scientific Reports
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens such as Mycobacterium tuberculosis and Toxoplasma gondii. Enhancement of P2X7 receptor responses may be useful in pathogen cleara
Publikováno v:
IndraStra Global.
Cells in their native environment are exposed to a milieu of biochemical and physical forces. Cellular physiology and function are affected by dynamic cell–cell and cell–matrix interactions and communication. Cells bind to the cellular or matrix
Publikováno v:
Biomedical Materials. 15:052002
The liver is a center of metabolic activity, including the metabolism of drugs, and consequently is prone to drug-induced liver injury. Failure to detect hepatotoxicity of drugs during their development will lead to the withdrawal of the drugs during
Publikováno v:
Journal of Neurochemistry. 134:819-832
GABAA receptors are pentameric ligand-gated ion channels that mediate inhibitory fast synaptic transmission in the central nervous system. Consistent with recent pentameric ligand-gated ion channels structures, sequence analysis predicts an α-helix