Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Brett, O'Brien"'
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
The engineering of switchable or activatable dCas9 proteins would benefit from a single system for both positive and negative selection of dCas9 activity. Most systems that are used to interrogate dCas9 libraries use a fluorescent protein screen or a
Externí odkaz:
https://doaj.org/article/f1a1e22722ad4d6689dca5d1901662aa
Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation (LBSL) is a rare neurological disorder caused by the mutations in the DARS2 gene, which encodes the mitochondrial aspartyl-tRNA synthetase. The objective of this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::153f4cc14231724a464710c0d303d8e5
https://doi.org/10.21203/rs.3.rs-2603446/v1
https://doi.org/10.21203/rs.3.rs-2603446/v1
Publikováno v:
AASV Annual Meeting.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4841185ab3d5eff38a41deccd0ad5dc
https://doi.org/10.54846/am2023/45
https://doi.org/10.54846/am2023/45
Publikováno v:
Molecular Cell. 83:1489-1501.e5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a779193c1f51b0408637dbfade2cd2c2
https://doi.org/10.1016/j.molcel.2023.04.003
https://doi.org/10.1016/j.molcel.2023.04.003
Autor:
Cara H. Olsen, William F. Blakely, Brett O'Brien, David L. Bolduc, Uma Subramanian, Maureen McNamara, Lyudmila Romanyukha
Publikováno v:
Health Physics. 119:52-58
The objective of this study was to establish radiation dose-response calibration curves using automated dicentric scoring to support rapid and accurate cytogenetic triage dose-assessment. Blood was drawn from healthy human volunteers and exposed to C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09545aac1b1d728b71c79503bd899915
https://doi.org/10.1097/hp.0000000000001285
https://doi.org/10.1097/hp.0000000000001285
Autor:
Nathalie Niyonzima, Jubayer Rahman, Natalia Kunz, Erin E. West, Tilo Freiwald, Jigar V. Desai, Nicolas S. Merle, Alexandre Gidon, Bjørnar Sporsheim, Michail S. Lionakis, Kristin Evensen, Beate Lindberg, Karolina Skagen, Mona Skjelland, Parul Singh, Markus Haug, Marieta M. Ruseva, Martin Kolev, Jack Bibby, Olivia Marshall, Brett O’Brien, Nigel Deeks, Behdad Afzali, Richard J. Clark, Trent M. Woodruff, Milton Pryor, Zhi-Hong Yang, Alan T. Remaley, Tom E. Mollnes, Stephen M. Hewitt, Bingyu Yan, Majid Kazemian, Máté G. Kiss, Christoph J. Binder, Bente Halvorsen, Terje Espevik, Claudia Kemper
Publikováno v:
Sci Immunol
While serum-circulating complement destroys invading pathogens, intracellularly active complement, termed the ‘complosome’, functions as a vital orchestrator of cell-metabolic events underlying T cell effector responses. Whether intracellular com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbdb6a3aa181bbb6e2cf643be663fb8
https://doi.org/10.1126/sciimmunol.abf2489
https://doi.org/10.1126/sciimmunol.abf2489
Autor:
Brett O’Brien, Brian J Greco, James R. Claus, Perle E Zhitnitskiy, Alejandro Ramirez, Arquimides Reyes, Angela Baysinger, Aaron Rendahl, Emily A Massie, Karly N Anderson, Jennifer Berger, Kurt D Vogel, Kaysie J Allen, Madonna Benjamin
Publikováno v:
J Anim Sci
Three penetrating captive bolt (PCB) placements were tested on cadaver heads from swine with estimated body weight (BW) >200 kg (sows = 232.9 ± 4.1 kg; boars = 229.3 ± 2.6 kg). The objectives were to determine tissue depth, cross-sectional brain ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2182149caf9efe232550901f876c61a2
https://doi.org/10.1093/jas/skab327
https://doi.org/10.1093/jas/skab327
Autor:
Chris D. Edwards, Edward Taylor, Rebecca H Graves, Olivia J. Robb, Brett O'Brien, Andrew W Harrell, Edith M. Hessel, Augustin Amour, Aarti Patel, Neil A Miller
Publikováno v:
Clinical pharmacokinetics. 61(2)
Physiologically based pharmacokinetic (PBPK) modelling has evolved to accommodate different routes of drug administration and enables prediction of drug concentrations in tissues as well as plasma. The inhalation route of administration has proven su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81f740786cad5a758f64fe8d78e115d
https://pubmed.ncbi.nlm.nih.gov/34458976
https://pubmed.ncbi.nlm.nih.gov/34458976
Autor:
Uma, Subramanian, Brett, O'Brien, Maureen, McNamara, Lyudmila, Romanyukha, David L, Bolduc, Cara, Olsen, William F, Blakely
Publikováno v:
Health physics. 119(1)
The objective of this study was to establish radiation dose-response calibration curves using automated dicentric scoring to support rapid and accurate cytogenetic triage dose-assessment. Blood was drawn from healthy human volunteers and exposed to C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85c48a7b2c5f90f8b681f98bae346a41
https://pubmed.ncbi.nlm.nih.gov/32483043
https://pubmed.ncbi.nlm.nih.gov/32483043
Autor:
Alejandro Ramirez, Madonna Benjamin, Kurt D Vogel, Angela Baysinger, Brett O’Brien, Karly N Anderson, James R. Claus, Arquimides Reyes
Publikováno v:
J Anim Sci
The objective of this study was to contrast the soft tissue thickness, cranial thickness, total tissue thickness, and cross-sectional brain area from the common frontal captive bolt placement for the captive bolt euthanasia of swine with the alternat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082bac634e975f30217f9dcf5af7c3a1
https://doi.org/10.1093/jas/skab054.009
https://doi.org/10.1093/jas/skab054.009