Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Bret R Sellman"'
Autor:
Antonio DiGiandomenico, Martijn A Spruit, Frits M E Franssen, Sami O Simons, Sander van Kuijk, Kristoffer Ostridge, Kiki Waeijen-Smit, Jessica Bonnell, Ulf Gehrmann, Bret R Sellman, Tara Kenny, Daphne Peerlings, Sarah Houben-Wilke
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) play a pivotal role in the burden and progressive course of chronic obstructive pulmonary disease (COPD). As such, disease management is predominantly based on the pre
Externí odkaz:
https://doaj.org/article/c1952e6d2e9d41989eb6d73c30b92c24
Autor:
Batu K Sharma‐Kuinkel, Christine Tkaczyk, Jessica Bonnell, Li Yu, Andrey Tovchigrechko, David E Tabor, Lawrence P Park, Felicia Ruffin, Mark T Esser, Bret R Sellman, Vance G Fowler Jr., Alexey Ruzin
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 7, Pp n/a-n/a (2019)
Abstract Objective To understand the relationships of Staphylococcus aureus (SA) bacteremic pneumonia (SABP) outcome with patient‐specific and SA‐specific variables. Methods We analysed SA bloodstream isolates and matching sera in SABP patients b
Externí odkaz:
https://doaj.org/article/8dae2678a14549b98b9ee2c93f92a312
Autor:
Saikat Paul, Olivia A. Todd, Kara R. Eichelberger, Christine Tkaczyk, Bret R. Sellman, Mairi C. Noverr, James E. Cassat, Paul L. Fidel, Brian M. Peters
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Candida albicans and Staphylococcus aureus are two commonly associated pathogens that cause nosocomial infections with high morbidity and mortality. Our prior and current work using a murine model of polymicrobial intra-abdominal infection (
Externí odkaz:
https://doaj.org/article/9af55269392f404dace79cc399b33b11
Autor:
Christine Tkaczyk, Melissa M Hamilton, Vivekananda Datta, Xiang Ping Yang, Jamese J Hilliard, Geoffrey L Stephens, Agnieszka Sadowska, Lei Hua, Terrence O'Day, JoAnn Suzich, Charles Kendall Stover, Bret R Sellman
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75103 (2013)
An optimal host response against Staphylococcus aureus skin and soft tissue infections (SSTI) is dependent on IL-1β and IL-17 mediated abscess formation. Alpha toxin (AT), an essential virulence factor for SSTI, has been reported to damage tissue in
Externí odkaz:
https://doaj.org/article/9b26e0d315cb455a87b1823dfc72e6a5
Autor:
Emmanuelle Gras, Trang T. T. Vu, Nhu T. Q. Nguyen, Vuvi G. Tran, Yanjie Mao, Nguyen D. Tran, Nam H. Mai, Oliver X. Dong, David H. Jung, Natalia L. P. P. Iorio, Helvecio C. C. Povoa, Marcos Gabriel Pinheiro, Fabio Aguiar-Alves, William J. Weiss, Bo Zheng, Lily I. Cheng, Charles K. Stover, Bret R. Sellman, Antonio DiGiandomenico, Laure Gibault, Florent Valour, Binh An Diep
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundNew drugs targeting antimicrobial resistant pathogens, including Pseudomonas aeruginosa, have been challenging to evaluate in clinical trials, particularly for the non-ventilated hospital-acquired pneumonia and ventilator-associated pneumon
Externí odkaz:
https://doaj.org/article/711b678c4c3e47ab9251fd8fcab51201
Autor:
Marta Szydlowska, Ginger Lasky, Stephanie Oldham, Cristian Rivera, Michael Ford, Bret R. Sellman, Christopher J. Rhodes, Taylor S. Cohen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1869:166697
Autor:
Christine Tkaczyk, Omari Jones-Nelson, Yue Yue Shi, David E. Tabor, Lily Cheng, Tianhui Zhang, Bret R. Sellman
Publikováno v:
mSphere. 7
Nonhealing diabetic foot ulcers (DFU), a major complication of diabetes, are associated with high morbidity and mortality despite current standard of care. Since Staphylococcus aureus is the most common pathogen isolated from nonhealing and infected
Autor:
Chiyun Lee, Junxia Lin, Andrzej Prokop, Vancheswaran Gopalakrishnan, Richard N. Hanna, Eliseo Papa, Adrian Freeman, Saleha Patel, Wen Yu, Monika Huhn, Abdul-Saboor Sheikh, Keith Tan, Bret R. Sellman, Taylor Cohen, Jonathan Mangion, Faisal M. Khan, Yuriy Gusev, Khader Shameer
Publikováno v:
Frontiers in Genetics. 13
Target prioritization is essential for drug discovery and repositioning. Applying computational methods to analyze and process multi-omics data to find new drug targets is a practical approach for achieving this. Despite an increasing number of metho
Autor:
Kiki Waeijen-Smit, Antonio DiGiandomenico, Jessica Bonnell, Kristoffer Ostridge, Ulf Gehrmann, Bret R Sellman, Tara Kenny, Sander van Kuijk, Daphne Peerlings, Martijn A Spruit, Sami O Simons, Sarah Houben-Wilke, Frits M E Franssen
Publikováno v:
BMJ Open. 13:e068787
IntroductionAcute exacerbations of chronic obstructive pulmonary disease (AECOPD) play a pivotal role in the burden and progressive course of chronic obstructive pulmonary disease (COPD). As such, disease management is predominantly based on the prev
Autor:
B. Weiner, J-C. Soria, Phillip A. Dennis, Matthew R. Henn, Christopher B. Ford, Jennifer R. Wortman, Vancheswaran Gopalakrishnan, Scott A. Hammond, Bret R. Sellman, D.J. Freeman
Publikováno v:
Immuno-Oncology and Technology, Vol 6, Iss, Pp 9-17 (2020)
Immunotherapies have drastically improved clinical outcomes in a wide range of malignancies. Nevertheless, patient responses remain highly variable, and reliable biomarkers that predict responses accurately are not yet fully understood. Compelling ev