Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bret Poat"'
Autor:
Partha K. Chandra, Sidhartha Hazari, Bret Poat, Feyza Gunduz, Ramesh Prabhu, Gerald Liu, Roberto Burioni, Massimo Clementi, Robert F. Garry, Srikanta Dash
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/885aca13b94348dba2784e5095bf96c3
Autor:
Partha K Chandra, Feyza Gunduz, Sidhartha Hazari, Ramazan Kurt, Rajesh Panigrahi, Bret Poat, David Bruce, Ari J Cohen, Humberto E Bohorquez, Ian Carmody, George Loss, Luis A Balart, Tong Wu, Srikanta Dash
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108616 (2014)
PurposeChronic Hepatitis C Virus (HCV)-infected patients with liver cirrhosis (LC) respond poorly to interferon-alpha (IFN-α) and ribavirin (RBV) combination therapy, but the reason for this is unclear. We previously reported that HCV-infection indu
Externí odkaz:
https://doaj.org/article/97b99bc571c9494aaab336ed28b36050
Autor:
Bret Poat, Sidhartha Hazari, Partha K Chandra, Feyza Gunduz, Luis A Balart, Xavier Alvarez, Srikanta Dash
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
We have developed multiple stable cell lines containing subgenomic HCV RNA that are resistant to treatment with interferon alpha (IFN-α. Characterization of these IFN-α resistant replicon cells showed defects in the phosphorylation and nuclear tran
Externí odkaz:
https://doaj.org/article/09855e38a5104502a9718a065e1e849c
Autor:
Bret Poat, Sidhartha Hazari, Partha K. Chandra, Feyza Gunduz, Luis A. Balart, Xavier Alvarez, Yong Zhang, Michael J. Holtzman, Srikanta Dash
Publikováno v:
PLoS ONE, Vol 5, Iss 11 (2010)
Externí odkaz:
https://doaj.org/article/5b76c9a198874723b4ebd54e87ec5c34
Autor:
George E. Loss, Feyza Gunduz, Srikanta Dash, Tong Wu, Ramazan Kurt, Rajesh Panigrahi, Sidhartha Hazari, Humberto E. Behorquez, David Bruce, Ian Carmody, Bret Poat, Partha K. Chandra, Ari J. Cohen, Luis A. Balart
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e108616 (2014)
PLoS ONE, Vol 9, Iss 9, p e108616 (2014)
PurposeChronic Hepatitis C Virus (HCV)-infected patients with liver cirrhosis (LC) respond poorly to interferon-alpha (IFN-α) and ribavirin (RBV) combination therapy, but the reason for this is unclear. We previously reported that HCV-infection indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c37828f03383fbdf9094b6ba6b9091
http://europepmc.org/articles/PMC4180933
http://europepmc.org/articles/PMC4180933
Hepatocellular carcinoma xenograft supports HCV replication: A mouse model for evaluating antivirals
Autor:
Bret Poat, Partha K. Chandra, Sidhartha Hazari, Tara G Ooms, Tong Wu, Srikanta Dash, Henry Hefler, Feyza Gunduz, Luis A. Balart
AIM: To develop a hepatocellular carcinoma (HCC) xenograft model for studying hepatitis C virus (HCV) replication in a mice, and antiviral treatment. METHODS: We developed a stable S3-green fluorescence protein (GFP) cell line that replicated the GFP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e94dfcd4d06d031dc7ee371426f6cf
https://europepmc.org/articles/PMC3022289/
https://europepmc.org/articles/PMC3022289/
Autor:
Luis A. Balart, Bret Poat, Partha K. Chandra, Srikanta Dash, Feyza Gunduz, Robert F. Garry, Xavier Alvarez, Sidhartha Hazari
Publikováno v:
Virology Journal, Vol 7, Iss 1, p 265 (2010)
Virology Journal
Virology Journal
Interferon alpha (IFN-α) binds to a cell surface receptor that activates the Jak-Stat signaling pathway. A critical component of this pathway is the translocation of interferon stimulated gene factor 3 (a complex of three proteins Stat1, Stat2 and I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ac85934f71350926adb95be9e86189
https://doi.org/10.1186/1743-422x-7-265
https://doi.org/10.1186/1743-422x-7-265
Autor:
Srikanta Dash, Sibnarayan Datta, Timothy P. Foster, Takaji Wakita, Bret Poat, Robert F. Garry, Sidhartha Hazari, Partha K. Chandra, Gus Kousoulas
Publikováno v:
Virology Journal
Virology Journal, Vol 7, Iss 1, p 36 (2010)
Virology Journal, Vol 7, Iss 1, p 36 (2010)
Background The sustained virological response to interferon-alpha (IFN-α) in individuals infected with hepatitis C virus (HCV) genotype 1 is only 50%, but is about 80% in patients infected with genotype 2-6 viruses. The molecular mechanisms explaini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f67d38e076754144cc80036bf2fa92
http://europepmc.org/articles/PMC2831880
http://europepmc.org/articles/PMC2831880
Autor:
Fatma M. Aboulnasr, Sidhartha Hazari, Partha K. Chandra, Feyza Gunduz, Luis A. Balart, Srikanta Dash, Darren P. Baker, Bret Poat
Publikováno v:
Virology Journal
Virology Journal, Vol 9, Iss 1, p 143 (2012)
Virology Journal, Vol 9, Iss 1, p 143 (2012)
Background Hepatic steatosis is recognized as a major risk factor for liver disease progression and impaired response to interferon based therapy in chronic hepatitis C (CHC) patients. The mechanism of response to interferon-alpha (IFN-α) therapy un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08037a124ae609a09aee3b1d5d96c681
Autor:
Sibnarayan Datta, Bret Poat, Hansjörg Hauser, Feyza Gunduz, Sidhartha Hazari, Partha K. Chandra, Luis A. Balart, Maria Samara, Mario Köster, William C. Wimley, Robert F. Garry, Srikanta Dash, Christophe Lamaze
Publikováno v:
Virology Journal, Vol 8, Iss 1, p 351 (2011)
Virology Journal
Virology Journal
The mechanisms underlying the Hepatitis C virus (HCV) resistance to interferon alpha (IFN-α) are not fully understood. We used IFN-α resistant HCV replicon cell lines and an infectious HCV cell culture system to elucidate the mechanisms of IFN-α r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be738c6a903c892444ecfdc5bf738cfb