Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Bret N Smith"'
Publikováno v:
Neurobiology of Disease, Vol 203, Iss , Pp 106737- (2024)
Parvalbumin-positive (PV+) GABAergic interneurons in the dentate gyrus provide powerful perisomatic inhibition of dentate granule cells (DGCs) to prevent overexcitation and maintain the stability of dentate gyrus circuits. Most dentate PV+ interneuro
Externí odkaz:
https://doaj.org/article/bcd3309bbe7d4b9eb6d86e8797b69ef9
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121022 (2015)
A variety of metabolic disorders, including complications experienced by diabetic patients, have been linked to altered neural activity in the dorsal vagal complex. This study tested the hypothesis that augmentation of N-Methyl-D-Aspartate (NMDA) rec
Externí odkaz:
https://doaj.org/article/a074a916b27249bb9835ce8066eab3bc
Autor:
Andrei V Derbenev, Bret N Smith
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70505 (2013)
Glucocorticoids influence vagal parasympathetic output to the viscera via mechanisms that include modulation of neural circuitry in the dorsal vagal complex, a principal autonomic regulatory center. Glucocorticoids can modulate synaptic neurotransmit
Externí odkaz:
https://doaj.org/article/09277d12661147f6b66f696ed225990e
Autor:
Muthu D Bhaskaran, Bret N Smith
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10683 (2010)
Temporal lobe epilepsy (TLE) is a neurological condition associated with neuron loss, axon sprouting, and hippocampal sclerosis, which results in modified synaptic circuitry. Cannabinoids appear to be anti-convulsive in patients and animal models of
Externí odkaz:
https://doaj.org/article/dc326b2268484bdd9c8657ff80c2a1f8
Publikováno v:
Frontiers in Systems Neuroscience, Vol 16 (2022)
Type A GABA receptors (GABAARs) are pentameric combinations of protein subunits that give rise to tonic (ITonicGABA) and phasic (i.e., synaptic; ISynapticGABA) forms of inhibitory GABAAR signaling in the central nervous system. Remodeling and regulat
Externí odkaz:
https://doaj.org/article/27934627001444ad9875ef0f9584ef15
Autor:
Young-Jin Kang, Sang-Hun Lee, Jeffery A. Boychuk, Corwin R. Butler, J. Anna Juras, Ryan A. Cloyd, Bret N. Smith
Publikováno v:
J Neurosci
Post-traumatic epilepsy (PTE) and behavioral comorbidities frequently develop after traumatic brain injury (TBI). Aberrant neurogenesis of dentate granule cells (DGCs) after TBI may contribute to the synaptic reorganization that occurs in PTE, but ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff2e676f29f922caa95ca703686311d
https://doi.org/10.1523/jneurosci.2263-21.2022
https://doi.org/10.1523/jneurosci.2263-21.2022
Autor:
Jelena A. Juras, Madison B. Webb, Lyndsay E.A. Young, Kia H. Markussen, Tara R. Hawkinson, Michael D. Buoncristiani, Kayli E. Bolton, Peyton T. Coburn, Meredith I. Williams, Lisa PY. Sun, William C. Sanders, Ronald C. Bruntz, Lindsey R. Conroy, Chi Wang, Matthew S. Gentry, Bret N. Smith, Ramon C. Sun
The brain metabolome directly connects to brain physiology and neuronal function. Brain glucose metabolism is highly heterogeneous among brain regions and continues postmortem. Therefore, challenges remain to capture an accurate snapshot of the physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f560559fad869ba985aef5cfcfce50b3
https://doi.org/10.1101/2022.08.16.504166
https://doi.org/10.1101/2022.08.16.504166
Autor:
Jelena A. Juras, Madison B. Webb, Lyndsay E.A. Young, Kia H. Markussen, Tara R. Hawkinson, Michael D. Buoncristiani, Kayli E. Bolton, Peyton T. Coburn, Meredith I. Williams, Lisa P.Y. Sun, William C. Sanders, Ronald C. Bruntz, Lindsey R. Conroy, Chi Wang, Matthew S. Gentry, Bret N. Smith, Ramon C. Sun
Publikováno v:
Cell Reports Methods. 3:100455
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b241412f2f9c0edbe5bcc980586b118
https://doi.org/10.1016/j.crmeth.2023.100455
https://doi.org/10.1016/j.crmeth.2023.100455
Autor:
Bret N. Smith, M Soledad Pitra
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Neurons in the brain stem dorsal vagal complex (DVC) take part in a continuous bidirectional crosstalk, in which they receive and respond to a vast array of signaling molecules, including glucose. Importantly, chronic dysregulation of blood glucose c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41116195927ad77e6a0b2837046edd6
https://doi.org/10.1152/ajpgi.00368.2020
https://doi.org/10.1152/ajpgi.00368.2020
Autor:
Amanda L Trout, Gregory J. Bix, Bret N. Smith, Stephen Grupke, Antonio Berretta, Andrew N. Clarkson, Ifechukwude Joachim Biose, Carie R. Boychuk, Aileen Marcelo, Jill Roberts, Danielle N. Edwards, Ibolya Rutkai, Michael P. Kahle, Amanda A. Gorman, Masafumi Ihara, Hatsue Ishibashi-Ueda, Emma K. Gowing, Jeffery A. Boychuk, Leon de Hoog
Publikováno v:
Translational Stroke Research
The extracellular matrix fragment perlecan domain V is neuroprotective and functionally restorative following experimental stroke. As neurogenesis is an important component of chronic post-stroke repair, and previous studies have implicated perlecan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43999c0374c37264151088c211a6d88
http://europepmc.org/articles/PMC7803718
http://europepmc.org/articles/PMC7803718