Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Brenton L. Scott"'
Autor:
Victoria eAlfaro, David L. Goldblatt, Gabriella R. Valverde, Mark eMunsell, Lee J. Quinton, Adam K. Walker, Robert eDantzer, Atul eVaradhachary, Brenton L. Scott, Scott E. Evans, Michael J. Tuvim, Burton F Dickey
Publikováno v:
Frontiers in Pharmacology, Vol 5 (2014)
We have previously discovered a synergistically therapeutic combination of two Toll-like receptor (TLR) ligands, an oligodeoxynucleotide (ODN) and Pam2CSK4. Aerosolization of these ligands stimulates innate immunity within the lungs to prevent pneumo
Externí odkaz:
https://doaj.org/article/a9c99de398994a0b8e8210007dbd1b7c
Autor:
Jocelyne M. Bray, Rena Johnson, Noah D. Cohen, Brenton L. Scott, Magnus Höök, Angela I. Bordin, Londa J. Berghaus, S. Giguère
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Pneumonia caused by the intracellular bacterium Rhodococcus equi is an important cause of disease and death in immunocompromised hosts, especially foals. Antibiotics are the standard of care for treating R. equi pneumonia in foals, and adjunctive the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6498e50dadaeb67e346a1fefe57cda
https://doi.org/10.1038/s41598-021-82049-y
https://doi.org/10.1038/s41598-021-82049-y
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 63:540-541
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e7371bb33bba7e14c989236341d929
https://doi.org/10.1165/rcmb.2020-0247le
https://doi.org/10.1165/rcmb.2020-0247le
Autor:
Michael J. Tuvim, Sofya Tkachman, Ana M. Jaramillo, Scott E. Evans, Jichao Chen, David Goldblatt, Belinda J. Hernandez, Brenton L. Scott, Carson T. Kirkpatrick, Burton F. Dickey, Jose R. Flores, Shradha Wali, Gabriella Valverde Ha, David Ost
Publikováno v:
Br J Pharmacol
Background and purpose Respiratory viral infections play central roles in the initiation, exacerbation and progression of asthma in humans. An acute paramyxoviral infection in mice can cause a chronic lung disease that resembles human asthma. We soug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d4e13408e1b04fbc933cda721e3a90
https://pubmed.ncbi.nlm.nih.gov/31968123
https://pubmed.ncbi.nlm.nih.gov/31968123
Autor:
Shradha Wali, Gabriella Valverde Ha, Scott E. Evans, Michael J. Tuvim, Ana M. Jaramillo, Sofya Tkachman, Jichao Chen, David Ost, Jose Roberto Flores Gonzalez, David Goldblatt, Brenton L. Scott, Carson T. Kirkpatrick, Burton F. Dickey, Belinda J. Hernandez
Respiratory viral infections play central roles in the initiation, exacerbation and progression of asthma in humans. An acute paramyxoviral infection in mice can cause a chronic lung disease that resembles human asthma. We sought to determine whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c714172a0b7e5b8bc7f6b63b3fab094
Autor:
Belinda J. Hernandez, Gabriella R. Valverde, D.L. Goldblatt, Brenton L. Scott, Jichao Chen, J.R. Flores Gonzalez, Burton F. Dickey, Michael J. Tuvim, Ana M. Jaramillo, Sofya Tkachman, Shradha Wali, S.E. Evans
Publikováno v:
A28. BACTERIAL AND VIRAL LUNG INFECTIONS AND PATHOGENESIS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d047d274d395331215d630bfc7ecad7c
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1208
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1208
Autor:
Jan Parker-Thornburg, Michael J. Tuvim, Roberto Adachi, Usman I. Nazeer, Junaid Farooq, Felicity Chung, Alan R. Burns, Lucia Piccotti, Brenton L. Scott, Joshua M. Brenner, Burton F. Dickey, Walter V. Velasco, Silvia M. Kreda, Anna Sofia Huerta Delgado, Ana M. Jaramillo, Christopher M. Evans, Zoulikha Azzegagh
Airway mucin secretion is necessary for ciliary clearance of inhaled particles and pathogens, but can be detrimental in pathologies such as asthma and cystic fibrosis. Exocytosis in mammals requires a Munc18 scaffolding protein, and airway secretory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7aec728654cb4ac45befed7ead08baa
https://europepmc.org/articles/PMC6483006/
https://europepmc.org/articles/PMC6483006/
Autor:
Scott E. Evans, Brian E. Gilbert, Diane C. Markesich, Miguel M. Leiva-Juarez, Brenton L. Scott, Michael J. Tuvim, Carson T. Kirkpatrick, Burton F. Dickey
Publikováno v:
European journal of pharmacology. 818
Influenza pneumonia remains a common and debilitating viral infection despite vaccination programs and antiviral agents developed for prophylaxis and treatment. The neuraminidase inhibitor oseltamivir is frequently prescribed for established influenz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4772bca2d6ba67dcaa38496e8f4c9d0
https://pubmed.ncbi.nlm.nih.gov/29066417
https://pubmed.ncbi.nlm.nih.gov/29066417
Autor:
Elsa M. Rodarte, Joo-Heon Yoon, Rustam Bagirzadeh, Zoulikha Azzegagh, Rupesh Nigam, James A. McNew, Binhui Ren, Brenton L. Scott, Youlia Petrova, Kyubo Kim, Michael J. Tuvim, Lucia Piccotti, Anurag Agrawal, Alejandra Gomez, Roberto Adachi, Christopher M. Evans, Burton F. Dickey, Vesa M. Olkkonen
Publikováno v:
Biochemical Journal
Airway mucin secretion and MC (mast cell) degranulation must be tightly controlled for homoeostasis of the lungs and immune system respectively. We found the exocytic protein Munc18b to be highly expressed in mouse airway epithelial cells and MCs, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a16dcc44d03feca71748d207a23da21
https://doi.org/10.1042/bj20120057
https://doi.org/10.1042/bj20120057
Autor:
Brenton L. Scott, Gary R. Klimpel, Gabriela Bowden, Dimitrios P. Kontoyiannis, P. Rocco LaSala, Johnny W. Peterson, Magnus Höök, Burton F. Dickey, Cecilia G. Clement, Russell E. Lewis, Jennifer Pawlik, Derek T. Larson, Scott E. Evans, Michael J. Tuvim, Yi Xu, Ashok K. Chopra
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Pneumonia is a serious problem worldwide. We recently demonstrated that innate defense mechanisms of the lung are highly inducible against pneumococcal pneumonia. To determine the breadth of protection conferred by stimulation of lung mucosal innate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810915fb0a7ddc8ba3c4333cee4b1d13
https://doi.org/10.1165/rcmb.2008-0260oc
https://doi.org/10.1165/rcmb.2008-0260oc