Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Brenton A. Wright"'
Publikováno v:
Digital Biomarkers, Vol 8, Iss 1, Pp 140-148 (2024)
Introduction: Essential tremor is a common movement disorder. Numerous validated clinical rating scales exist to quantify essential tremor severity by employing rater-dependent visual observation but have limitations, including the need for trained h
Externí odkaz:
https://doaj.org/article/e6a26ac2cdec43d6bac1a689aa4f690d
Autor:
Chihiro Sato, Nipun Mallipeddi, Nupur Ghoshal, Brenton A. Wright, Gregory S. Day, Albert A. Davis, Albert H. Kim, Gregory J. Zipfel, Randall J. Bateman, Audrey Gabelle, Nicolas R. Barthélemy
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 9, Pp 1817-1830 (2021)
Abstract Objective Tau hyperphosphorylation at threonine 217 (pT217) in cerebrospinal fluid (CSF) has recently been linked to early amyloidosis and could serve as a highly sensitive biomarker for Alzheimer’s disease (AD). However, it remains unclea
Externí odkaz:
https://doaj.org/article/11eeb562e9e94caa965224e960d99793
Autor:
Aristide Merola, Noelle Kobayashi, Alberto Romagnolo, Brenton A. Wright, Carlo Alberto Artusi, Gabriele Imbalzano, Irene Litvan, Amber D. Van Laar, Krystof Bankiewicz
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Introduction: We sought to provide an overview of the published and currently ongoing movement disorders clinical trials employing gene therapy, defined as a technology aiming to modulate the expression of one or more genes to achieve a therapeutic b
Externí odkaz:
https://doaj.org/article/aa5a46d6d5344a04a3e90c0cd221e93e
Autor:
Kanta Horie, Nicolas R. Barthélemy, Salvatore Spina, Lawren VandeVrede, Yingxin He, Ross W. Paterson, Brenton A. Wright, Gregory S. Day, Albert A. Davis, Celeste M. Karch, William W. Seeley, Richard J. Perrin, Rama K. Koppisetti, Faris Shaikh, Argentina Lario Lago, Hilary W. Heuer, Nupur Ghoshal, Audrey Gabelle, Bruce L. Miller, Adam L. Boxer, Randall J. Bateman, Chihiro Sato
Publikováno v:
Nature medicine, vol 28, iss 12
Despite recent advances in fluid biomarker research in Alzheimer’s disease (AD), there are no fluid biomarkers or imaging tracers with utility for diagnosis and/or theragnosis available for other tauopathies. Using immunoprecipitation and mass spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e9dc620bf8ff3656c93485d820998a
https://escholarship.org/uc/item/5z97w1k2
https://escholarship.org/uc/item/5z97w1k2
Autor:
Albert H. Kim, Gregory J. Zipfel, Gregory S. Day, Randall J. Bateman, Chihiro Sato, Nupur Ghoshal, Nipun Mallipeddi, Audrey Gabelle, Nicolas R. Barthélemy, Albert A. Davis, Brenton A Wright
Publikováno v:
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology, Vol 8, Iss 9, Pp 1817-1830 (2021)
Annals of Clinical and Translational Neurology, Vol 8, Iss 9, Pp 1817-1830 (2021)
Objective Tau hyperphosphorylation at threonine 217 (pT217) in cerebrospinal fluid (CSF) has recently been linked to early amyloidosis and could serve as a highly sensitive biomarker for Alzheimer’s disease (AD). However, it remains unclear whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787a2208f0195b008b3b5f939e0e1d70
http://europepmc.org/articles/PMC8419397
http://europepmc.org/articles/PMC8419397
Autor:
Brenton A Wright, Ece Bayram, Deborah L. Harrington, Qian Shen, Irene Litvan, Cailey Grembowski
Publikováno v:
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition, vol 28, iss 6
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn
Visuospatial working memory (WM) impairments in Parkinson's disease (PD) are more prominent and evolve earlier than verbal WM deficits, suggesting some differences in underlying pathology. WM is regulated by dopaminergic neurotransmission in the pref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a44c4beed786cfe4fa22bbcbd3bc18
https://doi.org/10.1080/13825585.2020.1828804
https://doi.org/10.1080/13825585.2020.1828804
Autor:
Shelby B. Hughes, Emma Churchill, Anna Smirnova, Andrew Hall, Braden Culbert, Chase Snell, Brenton A. Wright, Paul E. Gilbert, Jody Corey-Bloom
Publikováno v:
Parkinsonism & Related Disorders. 107:105272
Individuals with Huntington's disease (HD) commonly experience anosognosia, a lack of awareness of deficits. Thus, it is important to examine the accuracy of patient vs caregiver ratings on the basis of objective performance-based measures.The Anosog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52491703f5e7d4fe2800015377cefd7
https://doi.org/10.1016/j.parkreldis.2022.105272
https://doi.org/10.1016/j.parkreldis.2022.105272
Autor:
Katherine Longardner, Brenton A. Wright, Aljoharah Alakkas, Hyeri You, Ronghui Xu, Lin Liu, Fatta B. Nahab
Publikováno v:
PLOS ONE. 18:e0278262
Background Parkinson disease (PD) psychosis (PDP) is a disabling non-motor symptom. Pharmacologic treatment is limited to pimavanserin, quetiapine, and clozapine, which do not worsen parkinsonism. A Food and Drug Administration black box warning exis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f00eaaa59d4be61905bfc1fc9761cb6
https://doi.org/10.1371/journal.pone.0278262
https://doi.org/10.1371/journal.pone.0278262
Autor:
Chihiro Sato, Nipun Mallipeddi, Nupur Ghoshal, Brenton A. Wright, Gregory S. Day, Albert A. Davis, Albert H. Kim, Gregory J. Zipfel, Randall J. Bateman, Audrey Gabelle, Nicolas R. Barthelemy
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45019d4be770fee0d0e1ed979a3ff941
https://doi.org/10.1002/alz.055533
https://doi.org/10.1002/alz.055533
Autor:
Vanessa Goodwill, Brenton A Wright, Annie Hiniker, Donald P. Pizzo, Ian Dryden, Douglas Galasko, Ian R. A. Mackenzie, David G. Coughlin, Stephanie Lessig
Publikováno v:
Neuropathol Appl Neurobiol
Multiple system atrophy (MSA) is a sporadic neurodegenerative disease clinically marked by autonomic failure and variable degrees of parkinsonism and cerebellar ataxias. The average age of onset is in the sixth decade of life with a five-year surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96850ebe06fa6c5d27e20b662354b563
https://pubmed.ncbi.nlm.nih.gov/34847258
https://pubmed.ncbi.nlm.nih.gov/34847258