Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Brenten L. Heeke"'
Autor:
Eleanor M. Donnelly, Eric T. Quach, Terence M. Hillery, Brenten L. Heeke, Brooke R. Snyder, Chalonda R. Handy, Deirdre M. O'Connor, Nicholas M. Boulis, Thais Federici
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 3, Pp 992-998 (2012)
Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease, which is the leading genetic cause of mortality in children. To date no effective treatment exists for SMA. The genetic basis for SMA has been well documented as a mutatio
Externí odkaz:
https://doaj.org/article/8b865ceb2cc341f8b50a0739c7a8b385
Autor:
Eric T. Quach, Thais Federici, Nicholas M. Boulis, Chalonda R. Handy, Eleanor M. Donnelly, Brooke R. Snyder, Brenten L. Heeke, Deirdre M. O’Connor, Terence M. Hillery
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 3, Pp 992-998 (2012)
Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease, which is the leading genetic cause of mortality in children. To date no effective treatment exists for SMA. The genetic basis for SMA has been well documented as a mutatio
Autor:
Nicholas M. Boulis, Brenten L. Heeke, Brooke R. Snyder, Bethwel Raore, Thais Federici, Colin K. Franz, S. Kaye Spratt, Igor Radovitskiy, Michele A. Kliem, Emily M. Barrow
Publikováno v:
Amyotrophic Lateral Sclerosis. 12:331-339
Amyotrophic lateral sclerosis (ALS) is characterized by motor neuron loss leading to paralysis and death. Vascular endothelial growth factor (VEGF) has angiogenic, neurotrophic, and neuroprotective properties, and has preserved neuromuscular function
Autor:
Nicholas M. Boulis, Cary H. Leung, Michele A. Kliem, Brenten L. Heeke, Thais Federici, Scott W J McPhee, Brooke R. Snyder
Publikováno v:
Stereotactic and Functional Neurosurgery. 89:275-285
Background/Aims: Expression of the neuropeptide galanin in hippocampal neurons reduces seizures in the kainic acid rodent model of epilepsy. In order to translate these findings into a human clinical trial, the safety and feasibility of hippocampal a