Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Brent W. Winston"'
Autor:
Andréanne Côté, Chel Hee Lee, Sayed M. Metwaly, Christopher J. Doig, Graciela Andonegui, Bryan G. Yipp, Ken Kuljit S. Parhar, Brent W. Winston
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-11 (2024)
Abstract Background The Berlin definition of acute respiratory distress syndrome (ARDS) includes only clinical characteristics. Understanding unique patient pathobiology may allow personalized treatment. We aimed to define and describe ARDS phenotype
Externí odkaz:
https://doaj.org/article/51696785a6904045808d1662e524495c
Publikováno v:
BMC Neuroscience, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Diagnosis and prognostication of severe traumatic brain injury (sTBI) continue to be problematic despite years of research efforts. There are currently no clinically reliable biomarkers, though advances in protein biomarkers are b
Externí odkaz:
https://doaj.org/article/f43c8aa2f39c4ed3b056ecd11b8beb4d
Autor:
Mohammad M. Banoei, Chel Hee Lee, James Hutchison, William Panenka, Cheryl Wellington, David S. Wishart, Brent W. Winston, the Canadian biobank, database for Traumatic Brain Injury (CanTBI) investigators, the Canadian Critical Care Translational Biology Group (CCCTBG), the Canadian Traumatic Brain Injury Research, Clinical Network (CTRC)
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-15 (2023)
Abstract Background Prognostication is very important to clinicians and families during the early management of severe traumatic brain injury (sTBI), however, there are no gold standard biomarkers to determine prognosis in sTBI. As has been demonstra
Externí odkaz:
https://doaj.org/article/d4b7736cb1c043eca6df6e1e6ba4dcc7
Autor:
Mohammad M. Banoei, Lauralyn A. McIntyre, Duncan J. Stewart, Shirley H. J. Mei, David Courtman, Irene Watpool, John Granton, John Marshall, Claudia dos Santos, Keith R. Walley, Kenny Schlosser, Dean A. Fergusson, Brent W. Winston, on behalf of Canadian Critical Care Trials Group (CCCTG), on behalf of Canadian Critical Care Translational Biology Group (CCCTBG)
Publikováno v:
Metabolites, Vol 13, Iss 11, p 1142 (2023)
Sepsis is the result of an uncontrolled host inflammatory response to infection that may lead to septic shock with multiorgan failure and a high mortality rate. There is an urgent need to improve early diagnosis and to find markers identifying those
Externí odkaz:
https://doaj.org/article/3455d13757b24114a6f29090a6d96d18
Autor:
Mohammad Mehdi Banoei, Etienne Mahé, Adnan Mansoor, Douglas Stewart, Brent W. Winston, Hamid R. Habibi, Meer-Taher Shabani-Rad
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Follicular lymphoma (FL) is a cancer of B-cells, representing the second most common type of non-Hodgkin lymphoma and typically diagnosed at advanced stage in older adults. In contrast to the wide range of available molecular genetic data, l
Externí odkaz:
https://doaj.org/article/84f1a1a4a8c34049b95c7f12fef77762
Autor:
Terry Lee, PhD, Alessandro Cau, BSc, Matthew Pellan Cheng, MD, Adeera Levin, MD, Todd C. Lee, MD, Donald C. Vinh, MD, Francois Lamontagne, MD, Joel Singer, PhD, Keith R. Walley, MD, Srinivas Murthy, MD, David Patrick, MD, Oleksa G. Rewa, MD, Brent W. Winston, MD, John Marshall, MD, John Boyd, MD, Karen Tran, MD, Andre C. Kalil, MD, Russell Mcculoh, MD, Robert Fowler, MD, James M. Luther, MD, James A. Russell, MD
Publikováno v:
CJC Open, Vol 3, Iss 7, Pp 965-975 (2021)
Background: Angiotensin receptor blockers (ARBs) and/or angiotensin-converting enzyme (ACE) inhibitors could alter mortality from coronavirus disease 2019 (COVID-19), but existing meta-analyses that combined crude and adjusted results may be confound
Externí odkaz:
https://doaj.org/article/5553bc00956f4f2b90b366257853dc68
Autor:
Sarah A. Angus, William R. Henderson, Mohammad M. Banoei, Yannick Molgat‐Seon, Carli M. Peters, Hanna R. Parmar, Donald E. G. Griesdale, Mypinder Sekhon, Andrew William Sheel, Brent W. Winston, Paolo B. Dominelli
Publikováno v:
Physiological Reports, Vol 10, Iss 9, Pp n/a-n/a (2022)
Abstract Acute respiratory distress syndrome (ARDS) is a lung injury characterized by noncardiogenic pulmonary edema and hypoxic respiratory failure. The purpose of this study was to investigate the effects of therapeutic hypothermia on short‐term
Externí odkaz:
https://doaj.org/article/91e94144466446238527c9d31dc75f89
Autor:
Asher A. Mendelson, Casey Lansdell, Alison E. Fox-Robichaud, Patricia Liaw, Jaskirat Arora, Jean-François Cailhier, Gediminas Cepinskas, Emmanuel Charbonney, Claudia dos Santos, Dhruva Dwivedi, Christopher G. Ellis, Dean Fergusson, Kirsten Fiest, Sean E. Gill, Kathryn Hendrick, Victoria T. Hunniford, Paulina M. Kowalewska, Karla Krewulak, Christian Lehmann, Kimberly Macala, John C. Marshall, Laura Mawdsley, Braedon McDonald, Ellen McDonald, Sarah K. Medeiros, Valdirene S. Muniz, Marcin Osuchowski, Justin Presseau, Neha Sharma, Sahar Sohrabipour, Janet Sunohara-Neilson, Gloria Vázquez-Grande, Ruud A. W. Veldhuizen, Donald Welsh, Brent W. Winston, Ryan Zarychanski, Haibo Zhang, Juan Zhou, Manoj M. Lalu, Sepsis Canada’s National Preclinical Sepsis Platform
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract Despite decades of preclinical research, no experimentally derived therapies for sepsis have been successfully adopted into routine clinical practice. Factors that contribute to this crisis of translation include poor representation by precl
Externí odkaz:
https://doaj.org/article/9aeed005c2d54e4888a280f7bf96c4a3
Autor:
Mohammad M. Banoei, Hans J. Vogel, Aalim M. Weljie, Sachin Yende, Derek C. Angus, Brent W. Winston
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-16 (2020)
Abstract Introduction Pneumonia is the most common cause of mortality from infectious diseases, the second leading cause of nosocomial infection, and the leading cause of mortality among hospitalized adults. To improve clinical management, metabolomi
Externí odkaz:
https://doaj.org/article/7eb9662ec90742ba9a01d53c0d57ff33
Autor:
Mohammad M. Banoei, Hans J. Vogel, Aalim M. Weljie, Anand Kumar, Sachin Yende, Derek C. Angus, Brent W. Winston, the Canadian Critical Care Translational Biology Group (CCCTBG)
Publikováno v:
Critical Care, Vol 21, Iss 1, Pp 1-15 (2017)
Abstract Background Metabolomics is a tool that has been used for the diagnosis and prognosis of specific diseases. The purpose of this study was to examine if metabolomics could be used as a potential diagnostic and prognostic tool for H1N1 pneumoni
Externí odkaz:
https://doaj.org/article/0ef37f8fb07a4709bc3fb7054bb108db