Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brent V. Powell"'
Autor:
Brent V. Powell, Ashis K. Basu
Publikováno v:
Chemical Research in Toxicology. 33:604-613
6-Nitrochrysene (6-NC), the most potent carcinogen evaluated by the newborn mouse assay, is metabolically activated by nitroreduction and a combination of ring oxidation and nitroreduction pathways. The nitroreduction pathway yields three major DNA a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95dc96f1131253110395be95cbbcc93d
https://doi.org/10.1021/acs.chemrestox.9b00429
https://doi.org/10.1021/acs.chemrestox.9b00429
Autor:
Khayra Alabrash, Santosh K. Mandal, Tiara V. Hinton, Jiangnan Peng, Tijesunimi Odebode, Sabreea J. Parnell, Angela Winstead, Brent V. Powell, Jeanette A. Krause, Peter Y. Zavalij
Publikováno v:
J Organomet Chem
Tricarbonylrhenium(I)(α-diimine) complexes are of importance because of their strong cytotoxic and fluorescence properties. Syntheses of such complexes were achieved through a two-step process. First, the pentylcarbonato complexes, fac-(CO)(3)(α-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d36f09ef951c3be348cb0efcfe39f4d
https://europepmc.org/articles/PMC8095682/
https://europepmc.org/articles/PMC8095682/
Autor:
Brent V, Powell, Ashis K, Basu
Publikováno v:
Chemical research in toxicology. 33(2)
6-Nitrochrysene (6-NC), the most potent carcinogen evaluated by the newborn mouse assay, is metabolically activated by nitroreduction and a combination of ring oxidation and nitroreduction pathways. The nitroreduction pathway yields three major DNA a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40da7ee89a4a4453b23f179782523f96
https://pubmed.ncbi.nlm.nih.gov/31903755
https://pubmed.ncbi.nlm.nih.gov/31903755
Autor:
Benjamin J. Ryan, Haozhe Yang, Brent V. Powell, Bret D. Freudenthal, Ashis K. Basu, Jan Henric T. Bacurio, Marc M. Greenberg, Spandana Naldiga
Publikováno v:
DNA Repair (Amst)
Fapy•dG and 8-OxodGuo are formed in DNA from a common N7-dG radical intermediate by reaction with hydroxyl radical. Although cellular levels of Fapy•dG are often greater, its effects on replication are less well understood than those of 8-OxodGuo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99914fff4508f4e77341cc881683371b
https://doi.org/10.1016/j.dnarep.2021.103213
https://doi.org/10.1016/j.dnarep.2021.103213
Autor:
Brent V. Powell, Roosevelt Shaw, Alexis Barfield, Arnold L. Rheingold, Sujan Ghimire, Monet Stevenson, Douglas M. Ho, Saroj K. Pramanik, Jeanette A. Krause, Chao Chen, Tiara V. Hinton, Dipak Giri, Paul T. Wilder, Santosh K. Mandal, Angela Winstead, Pola Olczak, James M. Wachira, Samira Azemati, Tijesunimi Odebode, Hirendra N. Banerjee, Yongchao Zhang, Pumtiwitt C. McCarthy, James A. Golen, Peter Y. Zavalij, David J. Weber, Solomon Tadesse, Sabreea J. Parnell
Publikováno v:
Mol Cell Biochem
Cisplatin and other metal-based drugs often display side effects and tumor resistance after prolonged use. Because rhenium-based anticancer complexes are often less toxic, a novel series of organorhenium complexes were synthesized of the types: XRe(C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055444d774f2be768719004dd83f441c
https://doi.org/10.1007/s11010-017-3181-z
https://doi.org/10.1007/s11010-017-3181-z
Publikováno v:
DNA Repair (Amst)
6-Nitrochrysene (6-NC) is a potent mutagen in bacteria and carcinogenic in animals. It is the most potent carcinogen ever tested in newborn mouse assay. DNA lesions resulting from 6-NC modification are likely to induce mutations if they are not remov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d079dcc7c5bb3aef512fc6988f8a4c60
https://doi.org/10.1016/j.dnarep.2020.102935
https://doi.org/10.1016/j.dnarep.2020.102935
Autor:
Ava Boston, Gabriel Thorne, Josiah Sampson, Santosh K. Mandal, Roosevelt Shaw, Brent V. Powell, Pola Olczak, Angela Winstead, Deidre Vaughan, Hirendra N. Banerjee, Vinod Manglik, Gloria Payne
Publikováno v:
Journal of cancer science & therapy
Purpose: Because of the scarcity of suitable brain cancer drugs, researchers are frantically trying to discover novel and highly potent drugs free of side effects and drug-resistance. Rhenium compounds are known to be nontoxic and exhibit no drug res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d08bd3c8512d6922fc801b42c797dc
https://doi.org/10.4172/1948-5956.1000512
https://doi.org/10.4172/1948-5956.1000512