Zobrazeno 1 - 2
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pro vyhledávání: '"Brent Steer"'
Autor:
Carola Sjolin, Brent Steer, Annie Lu, Geraldine Kent, Gregory P. Downey, Yi Jun Wu, Janet F. Forstner, Vera Cherapanov, George Thanassoulis, Colin McKerlie, Uma Sajjan, Ori D. Rotstein
Publikováno v:
Infection and Immunity. 69:5138-5150
Progressive pulmonary infection is the dominant clinical feature of cystic fibrosis (CF), but the molecular basis for this susceptibility remains incompletely understood. To study this problem, we developed a model of chronic pneumonia by repeated in
Autor:
Jim Hu, Gregory P. Downey, Rosetta Belcastro, Brent Steer, David R. Koehler, Martin Post, Yanxia Wen, Vicky Hannam, A. Keith Tanswell
Publikováno v:
Molecular Therapy. 4:58-65
We have developed an expression cassette for cystic fibrosis (CF) gene therapy using control elements from the human cytokeratin 18 gene (KRT18, also known as K18). KRT18 is naturally expressed in a spatial pattern similar to that of CFTR, the gene m