Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Brent S. Gaylord"'
Publikováno v:
Advanced Materials. 16:2127-2132
Publikováno v:
Journal of the American Chemical Society. 126:16850-16859
The use of anionic water-soluble conjugated polymers (CPs) for sensing the presence of avidin by use of a biotin-modified fluorescence quencher was studied. The molecules involved in the study included poly[2-methoxy-5-(3'-propyloxysulfonate)-1,4-phe
Publikováno v:
Proceedings of the National Academy of Sciences. 101:11634-11639
We have investigated the energy transfer processes in DNA sequence detection by using cationic conjugated polymers and peptide nucleic acid (PNA) probes with ultrafast pump-dump-emission spectroscopy. Pump-dump-emission spectroscopy provides femtosec
Publikováno v:
Journal of the American Chemical Society. 126:5446-5451
Fluorescence spectra show that excitation of the cationic water-soluble conjugated polymer poly[(1,4-phenylene)-2,7-[9,9-bis(6'-N,N,N-trimethylammonium)-hexyl]fluorene diiodide] (1) results in inefficient fluorescence resonance energy transfer (FRET)
Publikováno v:
Advanced Functional Materials. 13:463-467
An improved synthetic approach was developed for the synthesis of 1,4-bis[9′,9′-bis(6″-(N,N,N-trimethylammonium)-hexyl)-fluoren-2′-yl]benzene tetrabromide (1a), 1,4-bis[9′,9′;9″,9″-tetra(6″′-(N,N,N-trimethylammonium)-hexyl)-7′,2
Publikováno v:
Journal of the American Chemical Society. 125:896-900
A sensor is provided that detects single-stranded deoxyribonucleic acid (ssDNA) with a specific base sequence. The ssDNA sequence sensor comprises an aqueous solution containing a cationic water-soluble conjugated polymer [in this case, poly(9,9-bis(
Publikováno v:
Nature protocols. 2(9)
A fluorescence-based microarray technique that does not require target DNA labeling is detailed. This 'label-free' approach utilizes a cationic, water-soluble conjugated polymer PFBT (poly[9,9'-bis(6''-(N,N,N-trimethylammonium)hexyl)fluorene-co-alt-4
Publikováno v:
Journal of the American Chemical Society. 128(26)
The ability of peptide nucleic acids (PNA) to form specific higher-order (i.e., three- and four-stranded) complexes with DNA makes it an ideal structural probe for designing strand-specific dsDNA biosensors. Higher-order complexes are formed between
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 102(1)
A strategy employing a combination of peptide nucleic acid (PNA) probes, an optically amplifying conjugated polymer (CP), and S1 nuclease enzyme is capable of detecting SNPs in a simple, rapid, and sensitive manner. The recognition is accomplished by
Publikováno v:
Journal of the American Chemical Society. 125(22)
The synthesis of 1,4-bis(9,9'-bis(3"-(N,N,N-trimethylammonium)-propyl)-2'-fluorenyl)benzene tetrabromide (C3), 1,4-bis(9,9'-bis(4"-(N,N,N-trimethylammonium)-butyl)-2'-fluorenyl)benzene tetrabromide (C4), 1,4-bis(9,9'-bis(6"-(N,N,N-trimethylammonium)-