Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Brent S, Abel"'
Autor:
Young Jae Bahn, Hariom Yadav, Paolo Piaggi, Brent S. Abel, Oksana Gavrilova, Danielle A. Springer, Ioannis Papazoglou, Patricia M. Zerfas, Monica C. Skarulis, Alexandra C. McPherron, Sushil G. Rane
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Understanding how skeletal muscle fiber proportions are regulated is vital to understanding muscle function. Oxidative and glycolytic skeletal muscle fibers differ in their contractile ability, mitochondrial activity, and metabolic properties. Fiber-
Externí odkaz:
https://doaj.org/article/e661227f09e44dff81ed08f7b6f00ce5
Autor:
Sai P. Pydi, Shanu Jain, Wesley Tung, Yinghong Cui, Lu Zhu, Wataru Sakamoto, Shalini Jain, Brent S. Abel, Monica C. Skarulis, Jie Liu, Thanh Huynh, Karel Pacak, Marc G. Caron, Oksana Gavrilova, Toren Finkel, Jürgen Wess
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Beta3-adrenergic receptor signaling regulates adipose tissue browning. Here, the authors show that barr2 regulates internalization of beta3-adrenergic receptors and that mice lacking barr2 in adipocytes are protected from diet-induced weight gain and
Externí odkaz:
https://doaj.org/article/db4766c456f2475085560b5fbc6645dc
Autor:
Waldemar B Minich, Brent S Abel, Christian Schwiebert, Tim Welsink, Petra Seemann, Rebecca J Brown, Lutz Schomburg
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
ContextSevere insulin resistance (IR) in the presence of insulin receptor autoantibodies (InsR-aAb) is known as type B insulin resistance (TBIR). Considerable progress in therapy has been achieved, but diagnosis and monitoring of InsR-aAb remains a c
Autor:
Ranganath Muniyappa, Shannon D. Sullivan, Sri Harsha Tella, Brent S. Abel, S. Mitchell Harman, Marc R. Blackman
Publikováno v:
Physiological Reports, Vol 5, Iss 23, Pp n/a-n/a (2017)
Abstract The known interactions between the somatotropic and hypothalamic‐pituitary‐gonadal (HPG) axes have not been well delineated in older individuals. Aging‐associated decline in insulin like growth factor‐1 (IGF‐1) levels has been prop
Externí odkaz:
https://doaj.org/article/d821165fa76444eaa335e4260539933d
Autor:
Fernando Corvillo, Brent S. Abel, Alberto López-Lera, Giovanni Ceccarini, Silvia Magno, Ferruccio Santini, David Araújo-Vilar, Rebecca J. Brown, Pilar Nozal, Margarita López-Trascasa
Acquired generalized lipodystrophy (AGL) is a rare condition characterized by massive loss of adipose tissue through the body, causing severe metabolic complications. Autoimmune destruction of adipocytes is strongly suspected based on the frequent as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1493ed07e7ce654e694de34f87812088
https://doi.org/10.2337/figshare.20163935.v1
https://doi.org/10.2337/figshare.20163935.v1
Autor:
Mary Walter, Andin Fosam, Brent S. Abel, Shanaz Sikder, Sri Harsha Tella, Andrea Mari, Ranganath Muniyappa
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 105:e1835-e1846
Background African Americans (AAs) are at a higher risk for developing type 2 diabetes compared with non-Hispanic whites (NHWs). The causal role of β-cell glucose sensitivity (β-GS) and insulin clearance in hyperinsulinemia in AA adults is unclear.
Autor:
Dalia Walzer, Adina F Turcu, Smita Jha, Brent S Abel, Richard J Auchus, Deborah P Merke, Rebecca J Brown
Publikováno v:
J Clin Endocrinol Metab
Context Syndromes of severe insulin resistance (SIR) include insulin receptoropathy, in which all signaling downstream of the insulin receptor is lost, and lipodystrophy, in which some signaling pathways are impaired and others preserved. Women with
Autor:
Lynnette K. Nieman, Karen Campbell, Nicola M. Neary, Rachel Acree, Brent S. Abel, Caitlin M Miller
Publikováno v:
J Endocr Soc
Context Cushing syndrome (CS) is associated with impaired health-related quality of life (HRQOL) even after surgical cure. Objective To characterize patient and provider perspectives on recovery from CS, drivers of decreased HRQOL during recovery, an
Autor:
Brent S. Abel, Anna Wolska, Alan T. Remaley, Sungyoung Auh, Rebecca J. Brown, Marissa Lightbourne, Ranganath Muniyappa, Yevgeniya Kushchayeva, Mary Walter, Robert D. Shamburek, Kristina I. Rother
Publikováno v:
J Endocr Soc
Context Lipodystrophy syndromes cause hypertriglyceridemia that improves with leptin treatment using metreleptin. Mechanisms causing hypertriglyceridemia and improvements after metreleptin are incompletely understood. Objective Determine relationship
Autor:
Juvianee Estrada-Veras, Georgios Z. Papadakis, Kevin O'Brien, Fady Hannah-Shmouni, Joanna Klubo-Gwiezdzinska, Rahul Dave, Monica C. Skarulis, Ninet Sinaii, Amit Tirosh, Skand Shekhar, William A. Gahl, Jorge A Irizarry-Caro, Brent S. Abel, Bernadette R. Gochuico
Publikováno v:
JAMA Network Open
Key Points Question What is the prevalence of hypothalamic-pituitary-thyroid dysfunction in patients with Erdheim-Chester disease (ECD)? Findings In this cross-sectional study of 61 patients with ECD, the prevalence of central and primary hypothyroid