Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Brent P. Lehman"'
Autor:
Clifford Dustin Rubinstein, Dalton T. McLean, Brent P. Lehman, Jennifer J. Meudt, Dominic T. Schomberg, Kathy J. Krentz, Jamie L. Reichert, Mark B. Meyer, Marie Adams, Charles M. Konsitzke, Dhanansayan Shanmuganayagam
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Genome editing in pigs has been made efficient, practical, and economically viable by the CRISPR/Cas9 platform, representing a promising new era in translational modeling of human disease for research and preclinical development of therapies and devi
Externí odkaz:
https://doaj.org/article/c901f93349584b52870a52843c992889
Autor:
Alexander R. Judkins, C. Dustin Rubinstein, Brian Na, Jaclyn A. Biegel, Brent P. Lehman, Marco Giovannini, Jennifer J. Meudt, Jeremie Vitte, Dhanansayan Shanmuganayagam, Jamie L. Reichert
Publikováno v:
Neuro-Oncology
Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant CNS tumor of children below 6 months of age. The majority of AT/RT demonstrate genomic alterations in the SMARCB1 gene. There are two major hurdles in the development of safe and e
Autor:
Kilby L. Willenburg, Dominic T. Schomberg, Ana Cecilia Escobar Lopez, Jamie L. Reichert, Brent P. Lehman, R. L. Monson, Jennifer J. Meudt, Kathleen J. Krentz, Clifford Dustin Rubinstein, Dhanansayan Shanmuganayagam, Keri D. Graff, Jennifer M. Frank
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
Molecular Microbiology. 98:193-207
Prokaryotes use subcellular compartments for a variety of purposes. An intriguing example is a family of complex subcellular organelles known as bacterial microcompartments (MCPs). MCPs are widely distributed among bacteria and impact processes rangi
Autor:
Sudeep Bhattacharyya, Ryan J. Andrews, Sanchita Hati, Samuel C. Fehling, Brent P. Lehman, Alexander M. Strom
Publikováno v:
Volume 14, Issue 2. 14
Inter-domain communication plays a key role in the function of modular proteins. Earlier studies have demonstrated that the coupling of domain motions is important in mediating site-to-site communications in modular proteins. In the present study, bi
Publikováno v:
Scientific Reports
The diversity of non-canonical amino acids (ncAAs) endows proteins with new features for a variety of biological studies and biotechnological applications. The genetic code expansion strategy, which co-translationally incorporates ncAAs into specific
Publikováno v:
Journal of bacteriology. 199(8)
Bacterial microcompartments (MCPs) are extremely large proteinaceous organelles that consist of an enzymatic core encapsulated within a complex protein shell. A key question in MCP biology is the nature of the interactions that guide the assembly of
Autor:
Sanchita Hati, Sudeep Bhattacharyya, Brent P. Lehman, Karin Musier-Forsyth, Arrianna M. Zirbes, Stephanie N. Tadayon, James M. Johnson, Alexander M. Strom, Brianne L. Sanford
Publikováno v:
Biochemistry. 52(25)
Aminoacyl-tRNA synthetases are multi-domain enzymes that catalyze covalent attachment of amino acids to their cognate tRNA. Cross-talk between functional domains is a prerequisite for this process. In the present study, we investigate the molecular m