Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Brent M. Wood"'
Publikováno v:
eLife, Vol 10 (2021)
Morphogen signaling proteins disperse across tissues to activate signal transduction in target cells. We investigated dispersion of Hedgehog (Hh), Wnt homolog Wingless (Wg), and Bone morphogenic protein homolog Decapentaplegic (Dpp) in the Drosophila
Externí odkaz:
https://doaj.org/article/40a224d6acb844b2b3ce4d52b35e33cb
Autor:
Stefano Morotti, M. Wallner, Samuel Sossalla, Michael Holzer, Julia Voglhuber, Donald M. Bers, Michael Sacherer, Ingrid Matzer, Stefan Wagner, Natasa Djalinac, Senka Ljubojevic-Holzer, Mahmoud Abdellatif, Simon Sedej, Snjezana Radulovic, Milan Ivanov, Burkert Pieske, Joan Heller Brown, Julie Bossuyt, Brent M. Wood, Anthony W. Herren, Dirk von Lewinski
Publikováno v:
Circulation Research
Rationale: CaMKII (Ca 2+ -Calmodulin dependent protein kinase) δC activation is implicated in pathological progression of heart failure (HF) and CaMKIIδC transgenic mice rapidly develop HF and arrhythmias. However, little is known about early spati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd778515605f5419b2ac8dc51b90f01
https://doi.org/10.1161/circresaha.120.316947
https://doi.org/10.1161/circresaha.120.316947
Publikováno v:
eLife, Vol 10 (2021)
Morphogen signaling proteins disperse across tissues to activate signal transduction in target cells. We investigated dispersion of Hedgehog (Hh), Wnt homolog Wingless (Wg), and Bone morphogenic protein homolog Decapentaplegic (Dpp) in the Drosophila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e61c00fb0d6db307097a1e6161c56ad
https://elifesciences.org/articles/71744
https://elifesciences.org/articles/71744
Publikováno v:
eLife
Morphogen signaling proteins disperse across tissues to activate signal transduction in target cells. We investigated dispersion of Hedgehog (Hh), Wnt homolog Wingless (Wg), and Bone morphogenic protein homolog Decapentaplegic (Dpp) in the Drosophila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02a3f13f1844e763960ef9aad16385c1
https://pubmed.ncbi.nlm.nih.gov/34292155
https://pubmed.ncbi.nlm.nih.gov/34292155
Autor:
Senka Ljubojevic-Holzer, Kathryn Helmstadter, Donald M. Bers, Khanha D. Taheri, Simon Sedej, Julie Bossuyt, Brent M. Wood, Jeffrey R. Erickson
Publikováno v:
Basic research in cardiology, vol 116, iss 1
Basic Research in Cardiology
Basic Research in Cardiology
Nuclear histone deacetylase 4 (HDAC4) represses MEF2-mediated transcription, implicated in the development of heart failure. CaMKII-dependent phosphorylation drives nucleus-to-cytoplasm HDAC4 shuttling, but protein kinase A (PKA) is also linked to HD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3494e576c5899f03f34bd4d0e81091d
https://escholarship.org/uc/item/8zt1x68n
https://escholarship.org/uc/item/8zt1x68n
Autor:
Danielle M. Jorgens, Thomas B. Kornberg, Hai Huang, Brent M Wood, Mark Terasaki, Valentina Baena
Publikováno v:
The Journal of Cell Biology
Wood et al. use EM to visualize cytonemes, the specialized filopodia that mediate cell–cell signaling. Cytonemes of Drosophila cells have regions defined by oscillating diameters and contents that include ER, mitochondria, and ribosomes. Cytonemes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbb04e1ec0a628ee897acb560c2ee2a
https://pubmed.ncbi.nlm.nih.gov/33734293
https://pubmed.ncbi.nlm.nih.gov/33734293
Cytonemes are specialized filopodia that mediate paracrine signaling in Drosophila and other animals. Studies using fluorescence confocal microscopy (CM) established their general paths, cell targets, and essential roles in signaling. To investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1bbc64e47c22941936397cb1079d039
https://doi.org/10.1101/2020.10.09.332676
https://doi.org/10.1101/2020.10.09.332676
Autor:
Senka, Ljubojevic-Holzer, Anthony W, Herren, Natasa, Djalinac, Julia, Voglhuber, Stefano, Morotti, Michael, Holzer, Brent M, Wood, Mahmoud, Abdellatif, Ingrid, Matzer, Michael, Sacherer, Snjezana, Radulovic, Markus, Wallner, Milan, Ivanov, Stefan, Wagner, Samuel, Sossalla, Dirk, von Lewinski, Burkert, Pieske, Joan Heller, Brown, Simon, Sedej, Julie, Bossuyt, Donald M, Bers
Publikováno v:
Circ Res
RATIONALE: Ca(2+)-Calmodulin dependent protein kinase (CaMKII) δC activation is implicated in pathological progression of heart failure (HF) and CaMKIIδC transgenic mice rapidly develop HF and arrhythmias. However, little is known about early spati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55eeff28e18f02b2531fd21b186f3d9a
https://pubmed.ncbi.nlm.nih.gov/32821022
https://pubmed.ncbi.nlm.nih.gov/32821022
Autor:
Maura Ferrero, Brent M. Wood, Donald M. Bers, Mitchell Simon, Chidera C. Alim, Julie Bossuyt, Natalie N. Pinna, Samuel Galice
Calcium-calmodulin dependent protein kinase IIδ (CaMKIIδ) is an important regulator of cardiac electrophysiology, calcium (Ca) balance, contraction, transcription, arrhythmias and progression to heart failure. CaMKII is readily activated at mouths
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7472d02be53ae392aae2ba51fb836b5
https://escholarship.org/uc/item/9524j1pk
https://escholarship.org/uc/item/9524j1pk
Autor:
Brent M. Wood, Julie Bossuyt
Publikováno v:
Frontiers in Pharmacology
Frontiers in pharmacology, vol 8, iss JAN
Frontiers in pharmacology, vol 8, iss JAN
Protein Kinase D isoforms (PKD 1-3) are key mediators of neurohormonal, oxidative, and metabolic stress signals. PKDs impact a wide variety of signaling pathways and cellular functions including actin dynamics, vesicle trafficking, cell motility, sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3ede49a9c8877d5332894f64102c62
https://pubmed.ncbi.nlm.nih.gov/28174535
https://pubmed.ncbi.nlm.nih.gov/28174535