Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Brent M Bijonowski"'
Publikováno v:
Organoids, Vol 2, Iss 4, Pp 239-255 (2023)
Organoids have emerged as a powerful tool for studying organ development, disease modeling, and drug discovery due to their ability to mimic the in vivo structure and function of organs in a three-dimensional in vitro model. During in vivo organ matu
Externí odkaz:
https://doaj.org/article/3adc396927154d549c396ce57e6b671b
Autor:
Brice Nzigou Mombo, Brent M. Bijonowski, Christopher A. Raab, Stephan Niland, Katrin Brockhaus, Marc Müller, Johannes A. Eble, Seraphine V. Wegner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract E-cadherin-based cell-cell adhesions are dynamically and locally regulated in many essential processes, including embryogenesis, wound healing and tissue organization, with dysregulation manifesting as tumorigenesis and metastasis. However,
Externí odkaz:
https://doaj.org/article/95180b5c11be448fa2645bf8fa403228
Autor:
Xuegang Yuan, Yijun Liu, Brent M. Bijonowski, Ang-Chen Tsai, Qin Fu, Timothy M. Logan, Teng Ma, Yan Li
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-15 (2020)
Yuan et al. characterise metabolic profiles of human mesenchymal stem cells (hMSCs) during cell expansion in culture. They find that late passage hMSCs exhibit a NAD + /NADH redox cycle imbalance and that adding NAD + precursor nicotinamide restores
Externí odkaz:
https://doaj.org/article/d6ede884d1f14ddf888a9033545f13b4
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Mesenchymal stem cell (MSC)-based therapy has shown great promises in various animal disease models. However, this therapeutic potency has not been well claimed when applied to human clinical trials. This is due to both the availability of M
Externí odkaz:
https://doaj.org/article/482015429f474ea69540a7f3390f307c
Autor:
Brent M Bijonowski, Qin Fu, Teng Ma, Yan Li, Xuegang Yuan, Timothy M. Logan, Ang-Chen Tsai, Yijun Liu
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-15 (2020)
Human mesenchymal stem cells (hMSCs) promote endogenous tissue regeneration and have become a promising candidate for cell therapy. However, in vitro culture expansion of hMSCs induces a rapid decline of stem cell properties through replicative senes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148719c40f0a142e6f13af851b09fb76
https://doaj.org/article/d6ede884d1f14ddf888a9033545f13b4
https://doaj.org/article/d6ede884d1f14ddf888a9033545f13b4
Publikováno v:
Biotechnol Bioeng
Protein homeostasis is critical for cellular function, as loss of homeostasis is attributed to aging and the accumulation of unwanted proteins. Human mesenchymal stem cells (MSCs) have shown promising therapeutic potential due to their impressive abi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03a09905232b4fd0c80d3b2e1ae4111
https://doi.org/10.1002/bit.27474
https://doi.org/10.1002/bit.27474
Autor:
Brent M. Bijonowski
Publikováno v:
Epigenetics to Optogenetics-A New Paradigm in the Study of Biology
Epigenetics to Optogenetics-A New Paradigm in the Study of Biology ISBN: 9781838809935
Biochemistry
Biochemistry-Epigenetics to Optogenetics-A New Paradigm in the Study of Biology
Epigenetics to Optogenetics-A New Paradigm in the Study of Biology ISBN: 9781838809935
Biochemistry
Biochemistry-Epigenetics to Optogenetics-A New Paradigm in the Study of Biology
Cell–cell adhesions are fundamental in regulating multicellular behavior and lie at the center of many biological processes from embryoid development to cancer development. Therefore, controlling cell–cell adhesions is fundamental to gaining insi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b449218d54e3e7abe5183a89445086f2
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Mesenchymal stem cell (MSC)-based therapy has shown great promises in various animal disease models. However, this therapeutic potency has not been well claimed when applied to human clinical trials. This is due to both the availability of MSCs at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7fa2dc17890892cc35add88361964ac
https://doi.org/10.1038/s41598-020-77288-4
https://doi.org/10.1038/s41598-020-77288-4
Autor:
Xuegang, Yuan, Yijun, Liu, Brent M, Bijonowski, Ang-Chen, Tsai, Qin, Fu, Timothy M, Logan, Teng, Ma, Yan, Li
Publikováno v:
Communications Biology
Human mesenchymal stem cells (hMSCs) promote endogenous tissue regeneration and have become a promising candidate for cell therapy. However, in vitro culture expansion of hMSCs induces a rapid decline of stem cell properties through replicative senes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f014e51e316605962a4f8b7226b746b
https://pubmed.ncbi.nlm.nih.gov/33319867
https://pubmed.ncbi.nlm.nih.gov/33319867
Publikováno v:
Tissue Eng Part A
The human brain formation involves complicated processing, which is regulated by a gene regulatory network influenced by different signaling pathways. The cross-regulatory interactions between elements of different pathways affect the process of cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209c1120107bc4829a1787a6d1d21bf9
https://pubmed.ncbi.nlm.nih.gov/31686622
https://pubmed.ncbi.nlm.nih.gov/31686622