Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Brent L. Nannenga"'
Publikováno v:
Journal of Structural Biology: X, Vol 9, Iss , Pp 100102- (2024)
Microcrystal electron diffraction (MicroED) has emerged as a powerful technique for unraveling molecular structures from microcrystals too small for X-ray diffraction. However, a significant hurdle arises with plate-like crystals that consistently or
Externí odkaz:
https://doaj.org/article/8535d678483245299ce21056f86413f3
Autor:
Brent L. Nannenga
Publikováno v:
IUCrJ, Vol 11, Iss 1, Pp 7-8 (2024)
This commentary describes a novel method for serial electron diffraction data collection in electron crystallography, utilizing a scanning transmission electron microscope to rapidly obtain patterns with low radiation dose. This approach, demonstrate
Externí odkaz:
https://doaj.org/article/ad244f2f430f4aa3b221e773755b825f
Autor:
Ryan Puskar, Chloe Du Truong, Kyle Swain, Saborni Chowdhury, Ka-Yi Chan, Shan Li, Kai-Wen Cheng, Ting Yu Wang, Yu-Ping Poh, Yuval Mazor, Haijun Liu, Tsui-Fen Chou, Brent L. Nannenga, Po-Lin Chiu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Cryo-EM reveals an asymmetric bacterial photosynthetic supercomplex built upon a homodimeric reaction center core. The structure provides mechanistic insights into light excitation transfer and a possible evolutionary transition intermediate of photo
Externí odkaz:
https://doaj.org/article/ca1fde03a9924a1988079932a5dcdece
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Metabolomics has emerged as a powerful discipline to study complex biological systems from a small molecule perspective. The success of metabolomics hinges upon reliable annotations of spectral features obtained from MS and/or NMR. In spite of tremen
Externí odkaz:
https://doaj.org/article/830be7100f9e46d2a0f3a56764daae9a
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Structural characterization of small molecules is a crucial component of organic synthesis. In this work, we applied microcrystal electron diffraction (MicroED) to analyze the structure of the product of an enzymatic reaction that was intended to pro
Externí odkaz:
https://doaj.org/article/fdd1b25f424c417b89c4258541a6fc6b
Autor:
Brent L. Nannenga
Publikováno v:
Structural Dynamics, Vol 7, Iss 1, Pp 014304-014304-7 (2020)
Microcrystal electron diffraction, or MicroED, is a method that is capable of determining structure from very small and thin 3D crystals using a transmission electron microscope. MicroED has been successfully used on microcrystalline samples, includi
Externí odkaz:
https://doaj.org/article/8b55ccdcdc5e4ba1a233a5b6c559d7d5
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
MicroED is a method which combines cryo-EM sample preparation and instrumentation, with electron and X-ray crystallography data analysis, and it has been employed to solve many protein crystal structures at high resolution. Initially, the main doubts
Externí odkaz:
https://doaj.org/article/7d826fbad97245268e720191c0268731
Autor:
Sankarsan Biswas, Sayan Banerjee, Milan A. Shlain, Andrey A. Bardin, Rein V. Ulijn, Brent L. Nannenga, Andrew M. Rappe, Adam B. Braunschweig
Publikováno v:
Faraday Discussions. 241:266-277
Unique and orthogonal photomechanochemical and photosolvochemical stereoselective routes for cycloaddition of acenaphthylene with high yields of syn and anti products are reported.
Publikováno v:
ACS Applied Bio Materials. 5:4696-4700
Methods that allow the study of the structure of proteins in complex with nanomaterials promise to enhance our understanding of how biological molecules interface with inorganic materials. We used single-particle cryo-electron microscopy (cryo-EM) to
Publikováno v:
bioRxiv
SUMMARYMicrocrystal electron diffraction (MicroED) is a powerful tool for determining high-resolution structures of microcrystals from a diverse array of biomolecular, chemical, and material samples. In this study, we apply MicroED to DNA crystals, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218e3043d9fddb8004db6e7150e1f70c
https://europepmc.org/articles/PMC10168392/
https://europepmc.org/articles/PMC10168392/