Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Brent Koehn"'
Autor:
Arta M Monjazeb, Julia K Tietze, Steven K Grossenbacher, Hui-Hua Hsiao, Anthony E Zamora, Annie Mirsoian, Brent Koehn, Bruce R Blazar, Jonathan M Weiss, Robert H Wiltrout, Gail D Sckisel, William J Murphy
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e102709 (2014)
We have previously demonstrated that immunotherapy combining agonistic anti-CD40 and IL-2 (IT) results in synergistic anti-tumor effects. IT induces expansion of highly cytolytic, antigen-independent "bystander-activated" (CD8(+)CD44high) T cells dis
Externí odkaz:
https://doaj.org/article/8cc561b24e474b77877ada18789ecaf1
Autor:
Teresa L. Ramos, Sara Bolivar-Wagers, Sujeong Jin, Govindarajan Thangavelu, Federico Simonetta, Po-Yu Lin, Toshihito Hirai, Asim Saha, Brent Koehn, Leon L. Su, Lora K. Picton, Jeanette Baker, Juliane K. Lohmeyer, Megan Riddle, Cindy Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, John E. Wagner, K. Christopher Garcia, Robert S. Negrin, Bruce R. Blazar
Publikováno v:
Blood. 141:1337-1352
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative option for patients with hematological disorders and bone marrow (BM) failure syndromes. Graft-versus-host disease (GVHD) remains a leading cause of morbidity posttransplant
Autor:
Jemma H. Larson, Sujeong Jin, Michael Loschi, Sara Bolivar Wagers, Govindarajan Thangavelu, Michael C. Zaiken, Cameron McDonald-Hyman, Asim Saha, Ethan G. Aguilar, Brent Koehn, Mark J. Osborn, Angela Panoskaltsis-Mortari, Kelli P.A. Macdonald, Geoffrey R. Hill, William J. Murphy, Jonathan S. Serody, Ivan Maillard, Leslie S. Kean, Sangwon V. Kim, Dan R. Littman, Bruce R. Blazar
Publikováno v:
American Journal of Transplantation.
Autor:
Jemma H Nicholls, Michael Loschi, Sujeong Jin, Sara Bolivar Wagers, Govindarajan Thangavelu, Michael C Zaiken, Cameron McDonald-Hyman, Asim Saha, Ethan G Aguliar, Brent Koehn, Mark J Osborn, Kelli P.A. MacDonald, Sangwon V Kim, Dan R Littman, Bruce R Blazar
Publikováno v:
The Journal of Immunology. 206:11.05-11.05
Damage to the gastrointestinal (GI) tract following hematopoietic stem cell transplant (HSCT) has been shown to drive the development of acute graft-versus-host disease (aGVHD). We have demonstrated clinically that infusing regulatory T-cells (Treg)
Autor:
Dawn K Reichenbach, Benjamin M Matta, Xiaoli Zhang, Brent Koehn, Lisa Mathews, Michelle J Smith, Colby J Feser, Robert Zeiser, Heth Roderick Turnquist, Bruce R Blazar
Publikováno v:
The Journal of Immunology. 196:140.33-140.33
Graft-versus-host disease (GVHD) is the leading complication and cause of mortality after allogeneic hematopoietic cell transplantation (allo-HCT). Recently, we reported that IL-33 released from tissue damaged during allo-HCT conditioning mediates pr
Autor:
Julia Tietze, Hui-Hua Hsiao, Brent Koehn, Danice Wilkins, Gail Sckisel, Bruce Blazar, William Murphy
Publikováno v:
The Journal of Immunology. 186:52.17-52.17
Systemic cancer immunotherapy (IT) with anti-CD40/IL-2 in mice leads to marked antigen-independent proliferation of CD44high CD8+ cells, which are NKG2D+/CD25- and do not upregulate PD1 significantly. Here we investigated the role of CD4+ T cells on