Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Brent J. Yamamoto"'
Autor:
Jonathan French, Alan C. Fisher, Brent J. Yamamoto, Natalya V. Serbina, Nestor Gonzales, Edward O'Connor, Lisa N. Henning, Annette M. Shadiack, Daniel C. Sanford, Sarah Carpenter, Gregory V. Stark, John Mondick, Leslie S. Casey
Publikováno v:
Antimicrobial Agents and Chemotherapy
Inhalational anthrax has high mortality even with antibiotic treatment, and antitoxins are now recommended as an adjunct to standard antimicrobial regimens. The efficacy of obiltoxaximab, a monoclonal antibody against anthrax protective antigen (PA),
Autor:
Daniel C. Sanford, Sarah Carpenter, Lisa N. Henning, Natalya V. Serbina, Nestor Gonzales, Edward O'Connor, Leslie S. Casey, Annette M. Shadiack, Brent J. Yamamoto
Publikováno v:
Antimicrobial Agents and Chemotherapy
The Centers for Disease Control and Prevention recommend adjunctive antitoxins when systemic anthrax is suspected. Obiltoxaximab, a monoclonal antibody against protective antigen (PA), is approved for treatment of inhalational anthrax in combination
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 339:509-518
The angiotensin IV analog norleual [Nle-Tyr-Leu-ψ-(CH(2)-NH(2))-Leu-His-Pro-Phe] has been shown recently to act as a hepatocyte growth factor (HGF)/Met antagonist capable of blocking the binding of HGF to the Met receptor, inhibiting HGF-dependent a
Publikováno v:
Progress in Neurobiology. 84:157-181
The renin-angiotensin system (RAS) mediates several classic physiologies including body water and electrolyte homeostasis, blood pressure, cyclicity of reproductive hormones and sexual behaviors, and the regulation of pituitary gland hormones. These
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 340(3)
The 6-AH family [D-Nle-X-Ile-NH-(CH(2))(5)-CONH(2); where X = various amino acids] of angiotensin IV (Ang IV) analogs binds directly to hepatocyte growth factor (HGF) and inhibit HGF's ability to form functional dimers. The metabolically stabilized 6
Publikováno v:
The FASEB Journal. 25
Autor:
Michael F. Sardinia, Zach J. Anderson, John A. Masino, Brent J. Yamamoto, Michael D. Varnum, Joseph W. Harding, Patrick D. Elias, Bryan D. Hudson, Alene T. McCoy, John W. Wright
The angiotensin (Ang) IV analog norleual [Nle-Tyr-Ile-ψ-(CH2-NH2)3-4-His-Pro-Phe] exhibits structural homology with the hinge (linker) region of hepatocyte growth factor (HGF) and is hypothesized to act as a hinge region mimic. Norleual competitivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39f4a95bce985e788bcd519ddce0394
https://europepmc.org/articles/PMC2846015/
https://europepmc.org/articles/PMC2846015/
Autor:
Michelle Mcmicheal, Malte F. Lange, Brent J. Yamamoto, Leen H. Kawas, Kevin J. Church, Joseph W. Harding
Publikováno v:
Cancer Research. 74:729-729
The primary purpose of this study was to demonstrate that the hepatocyte growth factor (HGF) antagonist norleual is capable of attenuating the cellular responses of cancer cells to HGF. The angiotensin IV analog norleual [Nle-Tyr-Ile-ψ-(CH2-NH2)3-4-
Publikováno v:
Cancer Research. 71:1356-1356
The central domain interface of the HGF referred to as the hinge region is critical for proper ligand (HGF) dimerization and activation. A peptide sequence representing the hinge region acts as a hinge region mimic, by binding directly to HGF and blo