Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Brent E. Korba"'
Autor:
Hanane Elayadi, Mohamed Mesnaoui, Brent E. Korba, Michael Smietana, Jean Jacques Vasseur, John A. Secrist, Hassan B. Lazrek
Publikováno v:
ARKIVOC, Vol 2012, Iss 8, Pp 76-89 (2012)
Externí odkaz:
https://doaj.org/article/1e25d6d999f041b588c9edcd1d16965d
Autor:
Maria, Arif, Tanmoy, Mondal, Asifa, Majeed, Christopher A, Loffredo, Brent E, Korba, Somiranjan, Ghosh
Publikováno v:
International journal of molecular sciences. 23(18)
Poor glycemic control and dyslipidemia are hallmarks of type 2 diabetes mellitus (T2DM), which predispose to cardiovascular diseases. Peroxisome proliferator-activated receptor-α (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e42d21f6103068d4e6555cc1aee2bbff
https://pubmed.ncbi.nlm.nih.gov/36142760
https://pubmed.ncbi.nlm.nih.gov/36142760
Publikováno v:
Journal of medicinal chemistry. 65(13)
Minor structural modifications of acyclic nucleoside phosphonates can dramatically affect their antiviral properties. This work discloses a shift in the selectivity spectrum of 3-hydroxy-2-(phosphonomethoxy)propyl (HPMP) nucleotides from herpesviruse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9aa80c2abb25759b2de3cb078fd3fa
https://pubmed.ncbi.nlm.nih.gov/35754374
https://pubmed.ncbi.nlm.nih.gov/35754374
Autor:
Eric L. Nuermberger, Karl-Dimiter Bissig, Larisa Y. Poluektova, Janice J. Endsley, Rajen Koshy, Selvakumar Subbian, Brendan K. Podell, Katrin Eichelberg, Angela Wahl, Petros C. Karakousis, Ramesh Akkina, Brigitte E. Sanders-Beer, Stephan Menne, Moses T. Bility, Daniel L. Barber, J. Victor Garcia, Alexander Ploss, Benjamin J. Burwitz, Richard Hafner, Brent E. Korba, Chris Lambros
Publikováno v:
Current HIV Research
The main advantage of animal models of infectious diseases over in vitro studies is the gain in the understanding of the complex dynamics between the immune system and the pathogen. While small animal models have practical advantages over large anima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bc74796179c5f6ecfe05916d1e53ba
https://doi.org/10.2174/1570162x18666191223114019
https://doi.org/10.2174/1570162x18666191223114019
Autor:
Gail N. Bland, Ruth Quartey, Somiranjan Ghosh, Thomas Nnanabu, Zarish Noreen, Charles D. Howell, Christopher A. Loffredo, Jyothirmai J. Simhadri, Brent E. Korba
Publikováno v:
ISEE Conference Abstracts. 2021
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd074a8f35717de02eb4ad37517260c5
https://doi.org/10.1289/isee.2021.p-141
https://doi.org/10.1289/isee.2021.p-141
Autor:
Federico Gago, María-José Camarasa, Graciela Andrei, Jan Balzarini, Brent E. Korba, Robert Snoeck, Gloria Fernández-Cureses, Pedro A. Sánchez-Murcia, Sonia de Castro
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Acyclic nucleoside phosphonates incorporating 2,4-diaminotriazine (DAT) as a 5-aza-analog of the 2,4-diamino-pyrimidine (DAPym) nucleobase present in PMEO-DAPyms have been synthesized. The lead PMEO-DAT is as inhibitory against HIV, HBV, MSV and VZV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ba7ee02235f2a03ee2fda9f7445633
https://doi.org/10.1016/j.antiviral.2015.08.006
https://doi.org/10.1016/j.antiviral.2015.08.006
Autor:
Alexei Medvedev, Rency S. Varghese, Habtom W. Ressom, Christopher A. Loffredo, Kirti Shetty, Bin Zhou, Brent E. Korba, Rabindra Roy, Prasanth Viswanathan, Kepher H. Makambi
Publikováno v:
Journal of General Virology. 96:2928-2937
Specific sequence changes in codons 70 and 91 of the hepatitis C virus genotype 1b (HCV GT1b) core gene have been associated with increased risk of hepatocellular carcinoma (HCC). Essentially all previous studies were conducted in Asian populations w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0521bcbdafda7cf9e4d54b001bc7cd1
https://doi.org/10.1099/jgv.0.000219
https://doi.org/10.1099/jgv.0.000219
Autor:
Steven De Jonghe, Shrinivas G. Dumbre, Chao Liu, Piet Herdewijn, Christophe Pannecouque, Brent E. Korba
L-α-2′-Deoxythreosyl nucleoside phosphonates and their phosphonodiamidate prodrugs with a hypoxanthine, 2,6-diaminopurine, 2-amino-6-cyclopropylaminopurine, 7-deazaadenine, 5-fluorouracil and 5-methylcytosine heterocycle as a nucleobase were synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11077db0df564a622550af336a2d4b45
https://lirias.kuleuven.be/handle/123456789/592271
https://lirias.kuleuven.be/handle/123456789/592271
Publikováno v:
Virology. 444:218-224
The human norovirus (NoV) polyprotein is cleaved into mature non-structural proteins by both mature NoV protease (Pro, NS6) and its un-cleaved precursor (ProPol, NS6-7). Processing order is well-established with ‘early’ and ‘late’ cleavages,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5207839d239f1e9ad7238dda463c6f0f
https://doi.org/10.1016/j.virol.2013.06.013
https://doi.org/10.1016/j.virol.2013.06.013
Publikováno v:
Virology. 438(1):20-27
A highly active, fluorescence-based, in vitro assay for human Norovirus protease from genogroup I and II viruses was optimized utilizing as little as 0.25 μM enzyme, pH 7.6, and substrate:enzyme of 50–100. Activity in Tris–HCl or sodium phosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad64b6be62bfc780672f44f140430c8