Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Brent Calder"'
Autor:
Chuan Gao, Jonathan McCafferty, Brent Calder, Matthew Meredith, Lisa Edelmann, Rebekah Zimmerman, Yoshiko Mito
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100514- (2023)
Externí odkaz:
https://doaj.org/article/27fae31267af42f684b9fca9267d0390
Autor:
Jung Yoon Park, Mi-Ook Cho, Shanique Leonard, Brent Calder, I Saira Mian, Woo Ho Kim, Susan Wijnhoven, Harry van Steeg, James Mitchell, Gijsbertus T J van der Horst, Jan Hoeijmakers, Pinchas Cohen, Jan Vijg, Yousin Suh
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2346 (2008)
Unrepaired or misrepaired DNA damage has been implicated as a causal factor in cancer and aging. Xpd(TTD) mice, harboring defects in nucleotide excision repair and transcription due to a mutation in the Xpd gene (R722W), display severe symptoms of pr
Externí odkaz:
https://doaj.org/article/8f121145a76c467c89138853ded00299
Autor:
JoAnn M. Tufariello, Christopher A. Kerantzas, Catherine Vilchèze, R. Brent Calder, Eric K. Nordberg, Jack A. Fischer, Travis E. Hartman, Eva Yang, Timothy Driscoll, Laura E. Cole, Robert Sebra, Shahina B. Maqbool, Alice R. Wattam, William R. Jacobs
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT Mycobacterium haemophilum is an emerging pathogen associated with a variety of clinical syndromes, most commonly skin infections in immunocompromised individuals. M. haemophilum exhibits a unique requirement for iron supplementation to suppo
Externí odkaz:
https://doaj.org/article/90a51ee400054f14b7349d432b7286d1
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 772:55-62
Recently, great progress has been made in single cell genomics and transcriptomics. Here, we present an integrative method, termed single-cell transcriptogenomics (SCTG), in which whole exome sequencing and RNA-seq is performed concurrently on single
Autor:
R Brent Calder1 bcalder@buckinstitute.org, Beems, Rudolf B2 r.beems@rivm.nl, van Steeg, Harry2 h.van.steeg@rivm.nl, Mian, I Saira1,3 smian@lbl.gov, Lohman, Paul HM2 lohmanp@xs4all.nl, Vijg, Jan1 jvijg@buckinstitute.org
Publikováno v:
BMC Bioinformatics. 2007, Vol. 8, p183-9. 9p. 4 Color Photographs, 4 Diagrams.
Autor:
Masako Suzuki, Andrew S McLellan, Robert A. Dubin, John M. Greally, Joseph Hargitai, R. Brent Calder, Aaron Golden, Qiang Jing, Pilib Ó Broin, David Moskowitz
Publikováno v:
Genomics. 100:345-351
The challenges associated with the management, analysis and interpretation of assays based on massively-parallel sequencing (MPS) are both individually complex and numerous. We describe what we believe to be the appropriate solution, one that represe
Publikováno v:
Current Protocols in Toxicology
Manganese is a metal that is required for optimal biological functioning of organisms. Absorption, cellular import and export, and excretion of manganese are all tightly regulated. While some genes involved in regulation, such as DMT-1 and ferroporti
Autor:
Jan Vijg, Gary B. Chisholm, Rumana Bahar, R. Brent Calder, Martijn E.T. Dollé, Bradley H Pollock, Ashley D. Denny, Rita A. Busuttil, Christoph Klein, Claudia H. Hartmann, Karl A. Rodriguez
Publikováno v:
Nature. 441:1011-1014
The accumulation of somatic DNA damage has been implicated as a cause of ageing in metazoa. One possible mechanism by which increased DNA damage could lead to cellular degeneration and death is by stochastic deregulation of gene expression. Here we d
Autor:
Ernesto Perez, Jan Vijg, Linda V. Chadwell, Anastasia Derventzi, R. Brent Calder, Ana Maria Garcia, Martha J. Lundell, Rita A. Busuttil, Martijn E.T. Dollé
Publikováno v:
Nature Methods. 4:401-403
Presently there are no good assays for comparing somatic mutation frequencies and spectra between different vertebrate and invertebrate organisms. Here we describe a new lacZ mutation reporter system in D. melanogaster, which complements existing sys
Autor:
R. Brent Calder, Monica Chung, Enver Akalin, Nicole Hayde, James Pullman, Graciela de Boccardo, Yi Bao, Bin Ye, Daniel Schwartz, Michelle Lubetzky, Maria Ajaimy
This study investigated the mechanisms involved in development of donor-specific antibody (DSA) and/or C4d-negative transplant glomerulopathy (TGP) by allograft gene expression profiles using microarrays.This cohort study was conducted in kidney tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5cd32042f0c9e8145ec161ef51b82f5
https://europepmc.org/articles/PMC3848403/
https://europepmc.org/articles/PMC3848403/