Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Brent C. Vander Wyk"'
Autor:
Ryan S. O’Dell, Adam P. Mecca, Ming-Kai Chen, Mika Naganawa, Takuya Toyonaga, Yihuan Lu, Tyler A. Godek, Joanna E. Harris, Hugh H. Bartlett, Emmie R. Banks, Victoria L. Kominek, Wenzhen Zhao, Nabeel B. Nabulsi, Jim Ropchan, Yunpeng Ye, Brent C. Vander Wyk, Yiyun Huang, Amy F. T. Arnsten, Richard E. Carson, Christopher H. van Dyck
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2021)
Abstract Background Attempts to associate amyloid-β (Aβ) pathogenesis with synaptic loss in Alzheimer’s disease (AD) have thus far been limited to small numbers of postmortem studies. Aβ plaque burden is not well-correlated with indices of clini
Externí odkaz:
https://doaj.org/article/bf54db7ecf0047c889104bb1723e1147
Autor:
Abha R. Gupta, Alexander Westphal, Daniel Y. J. Yang, Catherine A. W. Sullivan, Jeffrey Eilbott, Samir Zaidi, Avery Voos, Brent C. Vander Wyk, Pam Ventola, Zainulabedin Waqar, Thomas V. Fernandez, A. Gulhan Ercan-Sencicek, Michael F. Walker, Murim Choi, Allison Schneider, Tammy Hedderly, Gillian Baird, Hannah Friedman, Cara Cordeaux, Alexandra Ristow, Frederick Shic, Fred R. Volkmar, Kevin A. Pelphrey
Publikováno v:
Molecular Autism, Vol 8, Iss 1, Pp 1-17 (2017)
Abstract Background Childhood disintegrative disorder (CDD) is a rare form of autism spectrum disorder (ASD) of unknown etiology. It is characterized by late-onset regression leading to significant intellectual disability (ID) and severe autism. Alth
Externí odkaz:
https://doaj.org/article/e3a20041f8344991bd674cd9f3162b1d
Publikováno v:
Developmental Cognitive Neuroscience, Vol 13, Iss C, Pp 75-83 (2015)
Social exclusion elicits powerful feelings of negative affect associated with rejection. Additionally, experiencing social exclusion reliably recruits neural circuitry associated with emotion processing. Recent work has demonstrated abnormal neural r
Externí odkaz:
https://doaj.org/article/1c4415d1fe634187a620fe4edfc7bebb
Publikováno v:
Developmental Cognitive Neuroscience, Vol 8, Iss C, Pp 121-130 (2014)
Previous research has noted disrupted patterns of neural activation during emotion, processing in individuals with autism spectrum disorders (ASD). However, prior research relied on, designs that may place greater cognitive load on individuals with A
Externí odkaz:
https://doaj.org/article/1d8763ef23024160a525c048e3e64d22
Autor:
Adam P. Mecca, Ryan S. O'Dell, Emily S. Sharp, Emmie R. Banks, Hugh H. Bartlett, Wenzhen Zhao, Sylwia Lipior, Nina G. Diepenbrock, Ming‐Kai Chen, Mika Naganawa, Takuya Toyonaga, Nabeel B. Nabulsi, Brent C. Vander Wyk, Amy F. T. Arnsten, Yiyun Huang, Richard E. Carson, Christopher H. van Dyck
Publikováno v:
Alzheimer's & Dementia. 18:2527-2536
Publikováno v:
Ann Surg
ImportanceAs the population of the United States (US) ages, there is considerable interest in ensuring safe and high-quality surgical care for older persons. Yet, valid, generalizable data on the occurrence of major surgery in the geriatric populatio
Autor:
Ryan S. O'Dell, Joanna E. Harris, Christopher H. van Dyck, Victoria L. Kominek, Ming-Kai Chen, Brent C. Vander Wyk, Richard E. Carson, Nabeel Nabulsi, Hugh H. Bartlett, Takuya Toyonaga, Emmie R. Banks, Jim Ropchan, Yiyun Huang, Mika Naganawa, Yihuan Lu, Wenzhen Zhao, Adam P. Mecca, Tyler A. Godek, Yunpeng Ye, Amy F.T. Arnsten
Publikováno v:
The American Journal of Geriatric Psychiatry. 29:S37-S40
Introduction Synaptic loss is an early pathology in Alzheimer's disease (AD) and the major structural correlate of cognitive impairment. We have recently demonstrated extensive synaptic loss in the medial temporal and neocortical regions of participa
Autor:
Jayanta Mondal, Nabeel Nabulsi, Yiyun Huang, Jean-Dominique Gallezot, Mika Naganawa, Sjoerd J. Finnema, Hannah R. Michalak, Ming-Kai Chen, Brent C. Vander Wyk, Richard E. Carson, Takuya Toyonaga, Shu-fei Lin, Ryan S. O'Dell, Christopher H. van Dyck, Julia W. McDonald, Amy F.T. Arnsten, Adam P. Mecca
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 41:2395-2409
[11C]UCB-J PET for synaptic vesicle glycoprotein 2 A (SV2A) has been proposed as a suitable marker for synaptic density in Alzheimer’s disease (AD). We compared [11C]UCB-J binding for synaptic density and [18F]FDG uptake for metabolism (correlated
Autor:
Wenzhen Zhao, Christopher H. van Dyck, Ryan S. O'Dell, Tyler A. Godek, Mika Naganawa, Joanna E. Harris, Ming-Kai Chen, Brent C. Vander Wyk, Richard E. Carson, Pradeep Varma, Hugh H. Bartlett, Adam P. Mecca, Takuya Toyonaga, Nabeel Nabulsi, Yiyun Huang, Amy F.T. Arnsten
Publikováno v:
Alzheimer's & Dementia
Introduction Synaptic loss is a robust and consistent pathology in Alzheimer's disease (AD) and the major structural correlate of cognitive impairment. Positron emission tomography (PET) imaging of synaptic vesicle glycoprotein 2A (SV2A) has emerged
Autor:
Christopher H. van Dyck, Emily Sharp, Ryan S. O'Dell, Emmie R. Banks, Hugh H. Bartlett, Ming‐Kai Chen, Mika Naganawa, Takuya Toyonaga, Joanna E. Harris, Gessica S. Ni, Wenzhen Zhao, Nabeel B. Nabulsi, Brent C. Vander Wyk, Yiyun Huang, Amy F. T. Arnsten, Richard E. Carson, Adam P. Mecca
Publikováno v:
Alzheimer's & Dementia. 17