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Autor:
David A. Yeung, Ramesh K. Ganju, Carolyn Wang, Brent A. Weiss, Subhadip Das, Anjum Sohail, Andrew B. Herr, Nirvan Shanker, Jeanette L.C. Miller, Jack Wellmerling, Gunjan Agarwal, Rafael Fridman
Publikováno v:
Journal of Molecular Biology. 431:368-390
Discoidin domain receptors (DDR1 and DDR2) are receptor tyrosine kinases that signal in response to collagen. We had previously shown that collagen binding leads to clustering of DDR1b, a process partly mediated by its extracellular domain (ECD). In