Comment on: Amanitin intoxication

Autor: Anthony Scalzo, Brent Neuschwander-Tetri

Publikováno v: Clinical toxicology (Philadelphia, Pa.).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa221f45529200f91bc2899d8fd962c
https://pubmed.ncbi.nlm.nih.gov/36255346

Complexity of ballooned hepatocyte feature recognition: Defining a training atlas for artificial intelligence-based imaging in NAFLD

Autor: Elizabeth M. Brunt, Andrew D. Clouston, Zachary Goodman, Cynthia Guy, David E. Kleiner, Carolin Lackner, Dina G. Tiniakos, Aileen Wee, Matthew Yeh, Wei Qiang Leow, Elaine Chng, Yayun Ren, George Goh Boon Bee, Elizabeth E. Powell, Mary Rinella, Arun J. Sanyal, Brent Neuschwander-Tetri, Zobair Younossi, Michael Charlton, Vlad Ratziu, Stephen A. Harrison, Dean Tai, Quentin M. Anstee

Publikováno v: Journal of Hepatology

Histologically assessed hepatocyte ballooning is a key feature discriminating non-alcoholic steatohepatitis (NASH) from steatosis (NAFL). Reliable identification underpins patient inclusion in clinical trials and serves as a key regulatory-approved s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e564230025fb7d84730466476cea2c14
https://pubmed.ncbi.nlm.nih.gov/35090960

Comparison of clinical prediction rules for ruling out cirrhosis in nonalcoholic fatty liver disease (NAFLD)

Autor: Danielle, Brandman, Marie, Boyle, Stuart, McPherson, Mark L, Van Natta, Arun J, Sanyal, Kris, Kowdley, Brent, Neuschwander-Tetri, Naga, Chalasani, Manal F, Abdelmalek, Norah A, Terrault, Art, McCullough, Ricki, Bettencourt, Cyrielle, Caussy, David E, Kleiner, Cynthia, Behling, James, Tonascia, Quentin M, Anstee, Rohit, Loomba

Publikováno v: Aliment Pharmacol Ther
Alimentary Pharmacology and Therapeuthics
Alimentary Pharmacology and Therapeuthics, 2022, 55 (11), pp.1441-1451. ⟨10.1111/apt.16874⟩

International audience; BACKGROUND AND AIMS: Patients with nonalcoholic fatty liver disease (NAFLD) cirrhosis benefit from referral to subspecialty care. While several clinical prediction rules exist to identify advanced fibrosis, the cutoff for excl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b307082b387017591ccefc59cde55d4
https://pubmed.ncbi.nlm.nih.gov/35995744

Diagnostic Accuracy of Noninvasive Fibrosis Models to Detect Change in Fibrosis Stage

Autor: Mohammad Shadab Siddiqui, Goro Yamada, Raj Vuppalanchi, Mark Van Natta, Rohit Loomba, Cynthia Guy, Danielle Brandman, James Tonascia, Naga Chalasani, Brent Neuschwander-Tetri, Arun J. Sanyal, Daniela Allende, Srinivasan Dasarathy, Arthur J. McCullough, Revathi Penumatsa, Jaividhya Dasarathy, Joel E. Lavine, Manal F. Abdelmalek, Mustafa Bashir, Stephanie Buie, Anna Mae Diehl, Christopher Kigongo, Mariko Kopping, David Malik, Dawn Piercy, Oscar W. Cummings, Samer Gawrieh, Linda Ragozzino, Kumar Sandrasegaran, Elizabeth M. Brunt, Theresa Cattoor, Danielle Carpenter, Janet Freebersyser, Debra King, Jinping Lai, Brent A. Neuschwander-Tetri, Joan Siegner, Susan Stewart, Susan Torretta, Kristina Wriston, Maria Cardona Gonzalez, Jodie Davila, Manan Jhaveri, Kris V. Kowdley, Nizar Mukhtar, Erik Ness, Michelle Poitevin, Brook Quist, Sherilynn Soo, Brandon Ang, Cynthia Behling, Archana Bhatt, Michael S. Middleton, Claude Sirlin, Maheen F. Akhter, Nathan M. Bass, Ryan Gill, Bilal Hameed, Jacqueline Maher, Norah Terrault, Ashley Ungermann, Matthew Yeh, Sherry Boyett, Melissa J. Contos, Sherri Kirwin, Velimir A.C. Luketic, Puneet Puri, Jolene Schlosser, Mohammad S. Siddiqui, Leslie Yost-Schomer, Kathryn Fowler, David E. Kleiner, Edward C. Doo, Sherry Hall, Jay H. Hoofnagle, Jessica J. Lee, Patricia R. Robuck, Averell H. Sherker, Rebecca Torrance, Patricia Belt, Jeanne M. Clark, John Dodge, Michele Donithan, Erin Hallinan, Milana Isaacson, Mariana Lazo, Jill Meinert, Laura Miriel, Jacqueline Smith, Michael Smith, Alice Sternberg, Mark L. Van Natta, Annette Wagoner, Laura A. Wilson, Katherine Yates

Publikováno v: Clin Gastroenterol Hepatol

BACKGROUND & AIMS: Noninvasive methods are needed to determine disease stage in patients with nonalcoholic fatty liver disease (NAFLD). We evaluated the diagnostic performance of several widely available fibrosis models for the assessment of hepatic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695b774b9d7eab09c1fa94f370d11ffc
https://doi.org/10.1016/j.cgh.2018.12.031

Portal Chronic Inflammation in Nonalcoholic Fatty Liver Disease: An Histologic Marker of Advanced NAFLD Clinicopathologic Correlations from the NASH Clinical Research Network

Autor: Matthew M. Yeh, Patricia Belt, Linda D. Ferrell, Monique Rosenthal, Wana Kim, Manual Celedon, Kevin Edwards, Yao Chang Liu, Naga Chalasani, Jay E. Everhart, Rosemary Hollick, Nathan M. Bass, Linda Ragozzino, Jody Mooney, Aynur Unalp-Arida, Milana Isaacson, Melissa Smith, Denise Espinosa, Katherine P. Yates, Alison Lyndecker, Kavita Nair, James E. Nelson, Arun J. Sanyal, Aynur Unalp, Joan Siegner, Susana Mendoza, Diane Bringman, Kiran Bambha, Dawn Piercy, Margaret Stager, Melissa J. Contos, Claude B. Sirlin, Grace Gyurkey, Alice L. Sternberg, Ann O. Scheimann, Cynthia Behling, Jeffrey B. Schwimmer, Parvathi Mohan, Cynthia E. Behling, Ryan Colvin, Ann Klipsch, Sarah E. Barlow, Oscar W. Cummings, Ruth Sargent, Lydia Lee, Laura A. Wilson, Amy Jones, Marcia R. Gottfried, Anna Mae Diehl, Laura Miriel, Brent A. Neuschwander-Tetri, Michael Torbenson, David E. Kleiner, Manal F. Abdelmalek, Barbara Calabrese, Mika Green, Michel Donithan, Martin F. Graham, Kris V. Kowdley, Raj Vuppalanchi, Leanel Fairly, Elizabeth M. Brunt, Melissa J. Coffey, Arthur J. McCullough, Joyce Hoffmann, Paul G. Killenberg, Allison Tobin, Jose Derdoy, Melissa Young, Mark L. Van Natta, Janis Durelle, Susan Stewart, Prajakta Bhimalli, Cheryl Saunders, Judy Thompson, Michael Fuchs, Sherry Boyett, Daphne Bryan, Melanie B. White, Karen F. Murray, Srinivasan Dasarathy, Gilman D. Grave, Sarah Roberts, Tarek Hassanein, Edward Doo, Velimir A. Luketic, Jeanne M. Clark, Debra King, Fred Brancati, Alice Stead, Terry T.-K. Huang, Mark Pabst, James Tonascia, Tanya Stein, Laura Wilson, Brent A. Tetri, Bimalijit Sandhu, Danuta Filipowski, Kimberly Selph, Tessa Steel, Chia Wang, Yi Ping Pan, Raphael B. Merriman, Carol Hawkins, Debra Peglow, Nicholette Rogers, Joel E. Lavine, Stephanie H. Abrams, Philip J. Rosenthal, Leonard B. Seeff, Jay H. Hoofnagle, Diana Arceo, Girish Subbarao, Patricia R. Robuck, Carol Sargeant, Cynthia D. Guy, Lisa Clark, Jean P. Molleston, D Kleiner, Samantha Kwan

Adult nonalcoholic fatty liver disease (NAFLD) is characterized by absent or mild portal chronic inflammation (CI); in children, portal CI may be predominant. This study correlated clinical features with portal CI. Centrally-graded biopsies and tempo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3fe09ace37b2fcdcd43a698693a29d
https://europepmc.org/articles/PMC2928479/