Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Brent A. Rupnow"'
Autor:
Brent A. Rupnow, Tai W. Wong, R. Michael Lawrence, Malavi T. Madireddi, Jun Zhu, Wen-Pin Yang, Benjamin J. Henley, Joseph Fargnoli, Rolf-Peter Ryseck, Xinyu Wang, Jonathan G. Pabalan, Urvashi V. Roongta
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5f19996f7b7be9db5b7fb7f371b35a
https://doi.org/10.1158/1541-7786.22518582
https://doi.org/10.1158/1541-7786.22518582
Autor:
Brent A. Rupnow, Tai W. Wong, R. Michael Lawrence, Malavi T. Madireddi, Jun Zhu, Wen-Pin Yang, Benjamin J. Henley, Joseph Fargnoli, Rolf-Peter Ryseck, Xinyu Wang, Jonathan G. Pabalan, Urvashi V. Roongta
PDF file - 71K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26056af1bb8f6abaaf3538a0f9578a1c
https://doi.org/10.1158/1541-7786.22518573
https://doi.org/10.1158/1541-7786.22518573
Autor:
Brent A. Rupnow, Tai W. Wong, R. Michael Lawrence, Malavi T. Madireddi, Jun Zhu, Wen-Pin Yang, Benjamin J. Henley, Joseph Fargnoli, Rolf-Peter Ryseck, Xinyu Wang, Jonathan G. Pabalan, Urvashi V. Roongta
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec24b96c95c22de17c639d58869cf8e
https://doi.org/10.1158/1541-7786.22518576.v1
https://doi.org/10.1158/1541-7786.22518576.v1
Autor:
Brent A. Rupnow, Tai W. Wong, R. Michael Lawrence, Malavi T. Madireddi, Jun Zhu, Wen-Pin Yang, Benjamin J. Henley, Joseph Fargnoli, Rolf-Peter Ryseck, Xinyu Wang, Jonathan G. Pabalan, Urvashi V. Roongta
Emerging literature suggests that metabolic pathways play an important role in the maintenance and progression of human cancers. In particular, recent studies have implicated lipid biosynthesis and desaturation as a requirement for tumor cell surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1744961da814489eb070a9b55c9e7207
https://doi.org/10.1158/1541-7786.c.6542004
https://doi.org/10.1158/1541-7786.c.6542004
Autor:
Brent A. Rupnow, Tai W. Wong, R. Michael Lawrence, Malavi T. Madireddi, Jun Zhu, Wen-Pin Yang, Benjamin J. Henley, Joseph Fargnoli, Rolf-Peter Ryseck, Xinyu Wang, Jonathan G. Pabalan, Urvashi V. Roongta
PDF file - 39K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8112b61c9fece78abeaaa07d5a8f9ff9
https://doi.org/10.1158/1541-7786.22518579.v1
https://doi.org/10.1158/1541-7786.22518579.v1
Autor:
Subhasree Basu, Mike Russell, Katrin Sproesser, Bethany Mattson, Cassandra L. Lowenstein, Sathya Venkataramani, Maura Diamond, Robin E. Ernst, Stephen Jarantown, Jackson Wong, Gerald Chu, Kathryn Packman, Shaozhou Ken Tian, Scott R. Brodeur, Margaret Yu, Brent A. Rupnow
Publikováno v:
Cancer Research. 82:LB087-LB087
TMEFF2, a transmembrane protein with epidermal growth factor-like and 2 follistatin-like domains, is primarily restricted in expression to healthy brain and prostate and is enriched in prostate cancer. JNJ-70218902 (JNJ-902) is a bispecific antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2980c9759af2a1a5e7a0c3a0c62cc9b
https://doi.org/10.1158/1538-7445.am2022-lb087
https://doi.org/10.1158/1538-7445.am2022-lb087
Autor:
Peter J. Connolly, Zhuming Zhang, Jason E. Heindl, Mcdevitt Theresa Marie, Chris Janetopoulos, Gilles Bignan, Brent A. Rupnow, Jennifer R. Hertzog
Publikováno v:
The ProstateREFERENCES. 80(14)
Background Antiandrogens are effective therapies that block androgen receptor (AR) transactivation and signaling in over 50% of castration-resistant prostate cancer (CRPC) patients. However, an estimated 30% of responders will develop resistance to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cbf68fbadfe82e148f7bae965f519c4
https://pubmed.ncbi.nlm.nih.gov/33258507
https://pubmed.ncbi.nlm.nih.gov/33258507
Autor:
Thomas F. Westbrook, Jonathan Branch, Joseph Vacca, Julie Urgiles, Marius S. Pop, Christina Lee, Marco Gottardis, Ian Hickson, Peter J. Mikochik, Stefan Knapp, Ryan A. Stagg, Chris M. Wilfong, Norbert Bischofberger, Tamara D. Hopkins, Jost Vrabic Koren, Shelby K. Doyle, Sebastian Mathea, Brent A. Rupnow, Steven P. Balk, Deep Chatterjee, Hong Xin, Kristen L. Karlin, Douglas C. Saffran, Hua Gao, Nicholas B. Struntz, Gilles Bignan, David B. Freeman, Angela N. Koehler, Calla M. Olson, Sajjeev Jagannathan, B. Wesley Trotter, Brice Harrison Curtin, Charles Y. Lin, James R. Bischoff, Becky S Leifer, Florian Kabinger, Lori Westover, André Richters, Joshua W. Russo
Publikováno v:
Cell Chemical Biology. 28:134-147.e14
Summary Castration-resistant prostate cancers (CRPCs) lose sensitivity to androgen-deprivation therapies but frequently remain dependent on oncogenic transcription driven by the androgen receptor (AR) and its splice variants. To discover modulators o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e1e1f3eea8bcbb80f39ae718bc7146
https://doi.org/10.1016/j.chembiol.2020.10.001
https://doi.org/10.1016/j.chembiol.2020.10.001
Autor:
R. Michael Lawrence, Brent A. Rupnow, Malavi Madireddi, Xinyu Wang, Jonathan G. Pabalan, Tai W. Wong, Wen-Pin Yang, Benjamin J. Henley, Rolf-Peter Ryseck, Urvashi V. Roongta, Joseph Fargnoli, Jun Zhu
Publikováno v:
Molecular Cancer Research. 9:1551-1561
Emerging literature suggests that metabolic pathways play an important role in the maintenance and progression of human cancers. In particular, recent studies have implicated lipid biosynthesis and desaturation as a requirement for tumor cell surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c8e7f1c156e2966d8490facdb11d02
https://doi.org/10.1158/1541-7786.mcr-11-0126
https://doi.org/10.1158/1541-7786.mcr-11-0126
Autor:
Cindy Wang, Joan M. Carboni, Marco M. Gottardis, Ann Greer, David Bol, Amy Camuso, Aixin Li, Bruce Rowley, Warren Hurlburt, Brent A. Rupnow, Francis Y.F. Lee, Darryl L. Hadsell, Mark D. Wittman, Saulnier Mark G, Upender Velaparthi, Tai W. Wong, Mei-Li Wen, Kurt Zimmermann, Richard A. Westhouse, Adrian V. Lee, Ching Ping Ho
Publikováno v:
Cancer Research. 65:3781-3787
The insulin-like growth factor I receptor (IGF-IR) is a transmembrane tyrosine kinase that is essential to growth and development and also thought to provide a survival signal for the maintenance of the transformed phenotype. There has been increasin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c86c8d67f12be593606f26753f4d4c
https://doi.org/10.1158/0008-5472.can-04-4602
https://doi.org/10.1158/0008-5472.can-04-4602