Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Brent A. Neuschwander-Tetri"'
Autor:
Sandip Mukherjee, Molee Chakraborty, Eliwaza N. Msengi, Jake Haubner, Jinsong Zhang, Matthew J. Jellinek, Haley L. Carlson, Kelly Pyles, Barbara Ulmasov, Andrew J. Lutkewitte, Danielle Carpenter, Kyle S. McCommis, David A. Ford, Brian N. Finck, Brent A. Neuschwander-Tetri, Anutosh Chakraborty
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101767- (2023)
Objective: Defining the regulators of cell metabolism and signaling is essential to design new therapeutic strategies in obesity and NAFLD/NASH. E3 ubiquitin ligases control diverse cellular functions by ubiquitination-mediated regulation of protein
Externí odkaz:
https://doaj.org/article/b2642d46704a4c24822cb884661aab61
Autor:
Martin C. Sharpe, Kelly D. Pyles, Taylor Hallcox, Dakota R. Kamm, Michaela Piechowski, Bryan Fisk, Carolyn J. Albert, Danielle H. Carpenter, Barbara Ulmasov, David A. Ford, Brent A. Neuschwander-Tetri, Kyle S. McCommis, PhD
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 4, Pp 558-572 (2023)
Background and Aims: Polymorphisms near the membrane bound O-acyltransferase domain containing 7 (MBOAT7) genes are associated with worsened nonalcoholic fatty liver (NASH), and nonalcoholic fatty liver disease (NAFLD)/NASH may decrease MBOAT7 expres
Externí odkaz:
https://doaj.org/article/7425424d086845348870dd196c829045
Publikováno v:
Hepatology Communications, Vol 6, Iss 11, Pp 3003-3005 (2022)
Externí odkaz:
https://doaj.org/article/7b1f1fabeef74e44ab56fc6dda881c82
Autor:
Ryan M. Gill, Daniela Allende, Patricia H. Belt, Cynthia A. Behling, Oscar W. Cummings, Cynthia D. Guy, Daniela Carpenter, Brent A. Neuschwander-Tetri, Arun J. Sanyal, James Tonascia, Mark L. Van Natta, Laura A. Wilson, Goro Yamada, Matthew Yeh, David E. Kleiner, for the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)
Publikováno v:
Hepatology Communications, Vol 7, Iss 2, Pp e0033-e0033 (2023)
Background and Aims:. The NAFLD activity score was developed to measure histologic changes in NAFLD during therapeutic trials. Hepatocyte ballooning (HB) is the most specific feature in steatohepatitis diagnosis, yet the impact of variations in HB ha
Externí odkaz:
https://doaj.org/article/e064dc2fe4194521b39689b3632131c5
Autor:
A. Sidney Barritt, Stephanie Watkins, Norman Gitlin, Samuel Klein, Anna S. Lok, Rohit Loomba, Cheryl Schoen, K. Rajender Reddy, Huy Ngoc Trinh, Andrea R. Mospan, Miriam B. Vos, L. Michael Weiss, Kenneth Cusi, Brent A. Neuschwander‐Tetri, Arun J. Sanyal
Publikováno v:
Hepatology Communications, Vol 5, Iss 6, Pp 938-946 (2021)
Much of the current data on nonalcoholic fatty liver disease (NAFLD) are derived from biopsy‐based studies that may introduce ascertainment and selection bias. Selection of patients for liver biopsy has implications for clinical practice and the re
Externí odkaz:
https://doaj.org/article/cd7644ce825744c5998578481955510e
Autor:
Elizabeth Clearfield, Veronica Miller, Joseph Nadglowski, Katherine Barradas, Jennifer Al Naber, Arun J. Sanyal, Brent A. Neuschwander‐Tetri, Donna A. Messner, the coreNASH Panel
Publikováno v:
Hepatology Communications, Vol 5, Iss 5, Pp 774-785 (2021)
The increasing prevalence and burden of nonalcoholic steatohepatitis (NASH) has spurred the development of new treatments and a need to consider outcomes used for NASH treatment decision making. Development of a NASH core outcome set (COS) can help p
Externí odkaz:
https://doaj.org/article/63820c4e29ad4c09b5ddea4cab18df80
Autor:
Tinsay A. Woreta, Mark L. Van Natta, Mariana Lazo, Arunkumar Krishnan, Brent A. Neuschwander-Tetri, Rohit Loomba, Anna Mae Diehl, Manal F. Abdelmalek, Naga Chalasani, Samer Gawrieh, Srinivasan Dasarathy, Raj Vuppalanchi, Mohammad S. Siddiqui, Kris V. Kowdley, Arthur McCullough, Norah A. Terrault, Cynthia Behling, David E. Kleiner, Mark Fishbein, Paula Hertel, Laura A. Wilson, Emily P. Mitchell, Laura A. Miriel, Jeanne M. Clark, James Tonascia, Arun J. Sanyal, for the NASH Clinical Research Network
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Background and aims Management of patients with NASH who are at elevated risk of progressing to complications of cirrhosis (at-risk NASH) would be enhanced by an accurate, noninvasive diagnostic test. The new FAST™ score, a combination of FibroScan
Externí odkaz:
https://doaj.org/article/3774c2ebe409441cbe22e53a5e30eba8
Autor:
Sandip Mukherjee, Molee Chakraborty, Barbara Ulmasov, Kyle McCommis, Jinsong Zhang, Danielle Carpenter, Eliwaza Naomi Msengi, Jake Haubner, Chun Guo, Daniel P. Pike, Sarbani Ghoshal, David A. Ford, Brent A. Neuschwander-Tetri, Anutosh Chakraborty
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101364- (2021)
Objective: Obesity and insulin resistance greatly increase the risk of nonalcoholic fatty liver disease and steatohepatitis (NAFLD/NASH). We have previously discovered that whole-body and adipocyte-specific Ip6k1deletion protects mice from high-fat-d
Externí odkaz:
https://doaj.org/article/fd13f5e8e9714681819f553c2658c06f
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 3, Iss 4, Pp n/a-n/a (2020)
Abstract Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease and is associated with significant morbidity and mortality worldwide, with a high incidence in Western countries and non‐Western countries that have adopted
Externí odkaz:
https://doaj.org/article/0581343e6da440f3a80bebcef9500973
Autor:
Helen H. Wang, Tiangang Li, Piero Portincasa, David A. Ford, Brent A. Neuschwander-Tetri, Patrick Tso, David Q.-H. Wang
Publikováno v:
Liver Research, Vol 1, Iss 1, Pp 42-53 (2017)
Cholesterol gallstone formation represents a failure of biliary cholesterol homeostasis in which the physical-chemical balance of cholesterol solubility in bile is disturbed. Lithogenic bile is mainly caused by persistent hepatic hypersecretion of bi
Externí odkaz:
https://doaj.org/article/7d767dd77aeb4572a45a86d8a27d7b58