Optimum conditions for seed propagation of Garcinia brasiliensis: mimicking natural habitats allows better results

Autor: Amanda A. Cardoso, Sandro Barbosa, Breno R. Santos

Publikováno v: Journal of Seed Science, Vol 43 (2021)

Abstract: Garcinia brasiliensis is a tropical tree species of economic importance to local populations in the Amazon and Atlantic forests. The plant propagation of this species occurs mostly through seeds and despite that very little information abou

Externí odkaz: https://doaj.org/article/1ecf62ee6e784fa0906f9594587f2c3a

Favipiravir in patients hospitalised with COVID-19 (PIONEER trial): a multicentre, open-label, phase 3, randomised controlled trial of early intervention versus standard care

Autor: Pallav L Shah, Christopher M Orton, Beatriz Grinsztejn, Gavin C Donaldson, Brenda Crabtree Ramírez, James Tonkin, Breno R Santos, Sandra W Cardoso, Andrew I Ritchie, Francesca Conway, Maria P D Riberio, Dexter J Wiseman, Anand Tana, Bavithra Vijayakumar, Cielito Caneja, Craig Leaper, Bobby Mann, Anda Samson, Pankaj K Bhavsar, Marta Boffito, Mark R Johnson, Anton Pozniak, Michael Pelly, Damon Foster, Nadia Shabbir, Simon Connolly, Andrea Cartier, Sajjida Jaffer, Carmen Winpenny, Doris Daby, Samuel Pepper, Christine Adamson, Jamie Carungcong, Kribashnie Nundlall, Serge Fedele, Pardina Samson-Fessale, Alexandra Schoolmeesters, Laura Gomes de Almeida Martins, Rhian Bull, Patricia Correia Da Costa, Carina Bautista, Maria Eleanor Flores, Shameera Maheswaran, Lester Macabodbod, Rosalie Houseman, Marie-Louise Svensson, Amrinder Sayan, Carrie Fung, Justin Garner, Dilys Lai, Mark Nelson, Luke Moore, Shewta Gidwani, Gary Davies, Beatrice Ouma, Clovis Salinos, Jad Salha, Redasaad Yassein, Abdul Abbasi, Metod Oblak, Angelica Steward, Mini Thankachen, Amy Barker, Candida Fernandes, Veronica Beatriz, Leah Flores, Alfredo Soler-Carracedo, Alessandra Rocca, Carmela Martella, Charlotte Lloyd, Ciara Nolan, Latoya Horsford, Laura Martins, Lervina Thomas, Mark Winstanley, Miriam Bourke, Nicholas Branch, Orhan Orhan, Richard Morton, Sangeetha Saunder, Shashank Patil, Stephen Hughes, Wu Zhe, Ashley De Leon, Ayaan Farah, Grace Rya, Katrin Alizadeh, Kirsty Leong, Laure Trepte, Nupur Goel, Patrick McGown, Ursula Kirwan, Tamiris Vilela Baião, Luana Marins, Sandro Nazer, Raquel Malaguthi de Souza, Marcella Feitosa, Flavia Lessa, Elizabeth Silva de Magalhães, Jamile Costenaro, Rita de Cassia Alves Lira, Ana Carolina, Andréa Cauduro de Castro, Andre Machado Da Silva, Dimas Kliemann, Rita De Cassia Alves Lira, Gemma Walker, Donna Norton, Vicki Lowthorpe, Monica Ivan, Patrick Lillie, Nicholas Easom, Juan Sierra Madero, Álvaro López Iñiguez, Guadalupe Patricia Muñuzuri Nájera, Claudia Paola Alarcón Murra, Audelia Alanis Vega, Teresa Muñoz Trejo, Olivia Pérez Rodríguez

Publikováno v: The Lancet Respiratory Medicine. 11:415-424

COVID-19 has overwhelmed health services globally. Oral antiviral therapies are licensed worldwide, but indications and efficacy rates vary. We aimed to evaluate the safety and efficacy of oral favipiravir in patients hospitalised with COVID-19.We co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f0e6ef99a6e8cee9a438b2282c5402
https://doi.org/10.1016/s2213-2600(22)00412-x

Third‐line antiretroviral therapy, including raltegravir (RAL), darunavir (DRV/r) and/or etravirine (ETR), is well tolerated and achieves durable virologic suppression over 144 weeks in resource‐limited settings: ACTG A5288 strategy trial

Autor: Anchalee, Avihingsanon, Michael D, Hughes, Robert, Salata, Catherine, Godfrey, Caitlyn, McCarthy, Peter, Mugyenyi, Evelyn, Hogg, Robert, Gross, Sandra W, Cardoso, Aggrey, Bukuru, Mumbi, Makanga, Sharlaa, Badal-Aesen, Vidya, Mave, Beatrice Wangari, Ndege, Sandy Nerette, Fontain, Wadzanai, Samaneka, Rode, Secours, Marije, Van Schalkwyk, Rosie, Mngqibisa, Lerato, Mohapi, Javier, Valencia, Patcharaphan, Sugandhavesa, Esmelda, Montalban, Cornelius, Munyanga, Maganizo, Chagomerana, Breno R, Santos, Nagalingeswaran, Kumarasamy, Cecilia, Kanyama, Robert T, Schooley, John W, Mellors, Carole L, Wallis, Ann C, Collier, Beatriz, Grinsztejn

Publikováno v: Journal of the International AIDS Society. 25

ACTG A5288 was a strategy trial conducted in diverse populations from multiple continents of people living with HIV (PLWH) failing second-line protease inhibitor (PI)-based antiretroviral therapy (ART) from 10 low- and middle-income countries (LMICs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dec7c1ab2a5a98c1631e9fb54babf6
https://doi.org/10.1002/jia2.25905

Antiretroviral Therapy for the Prevention of HIV-1 Transmission

Autor: Myron S, Cohen, Ying Q, Chen, Marybeth, McCauley, Theresa, Gamble, Mina C, Hosseinipour, Nagalingeswaran, Kumarasamy, James G, Hakim, Johnstone, Kumwenda, Beatriz, Grinsztejn, Jose H S, Pilotto, Sheela V, Godbole, Suwat, Chariyalertsak, Breno R, Santos, Kenneth H, Mayer, Irving F, Hoffman, Susan H, Eshleman, Estelle, Piwowar-Manning, Leslie, Cottle, Xinyi C, Zhang, Joseph, Makhema, Lisa A, Mills, Ravindre, Panchia, Sharlaa, Faesen, Joseph, Eron, Joel, Gallant, Diane, Havlir, Susan, Swindells, Vanessa, Elharrar, David, Burns, Taha E, Taha, Karin, Nielsen-Saines, David D, Celentano, Max, Essex, Sarah E, Hudelson, Andrew D, Redd, Thomas R, Fleming, Robert, Bollinger

Publikováno v: The New England journal of medicine, vol 375, iss 9

BackgroundAn interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked infections caused by human immunodeficiency virus type 1 (HIV-1) in s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a8eed5e7e5c3962262d9d8df7d60c1
https://doi.org/10.1056/nejmoa1600693

Timing of Antiretroviral Therapy for HIV-1 Infection and Tuberculosis

Autor: Diane V, Havlir, Michelle A, Kendall, Prudence, Ive, Johnstone, Kumwenda, Susan, Swindells, Sarojini S, Qasba, Anne F, Luetkemeyer, Evelyn, Hogg, James F, Rooney, Xingye, Wu, Mina C, Hosseinipour, Umesh, Lalloo, Valdilea G, Veloso, Fatuma F, Some, N, Kumarasamy, Nesri, Padayatchi, Breno R, Santos, Stewart, Reid, James, Hakim, Lerato, Mohapi, Peter, Mugyenyi, Jorge, Sanchez, Javier R, Lama, Jean W, Pape, Alejandro, Sanchez, Aida, Asmelash, Evans, Moko, Fred, Sawe, Janet, Andersen, Ian, Sanne, Kuku, Appiah

Publikováno v: New England Journal of Medicine. 365:1482-1491

Antiretroviral therapy (ART) is indicated during tuberculosis treatment in patients infected with human immunodeficiency virus type 1 (HIV-1), but the timing for the initiation of ART when tuberculosis is diagnosed in patients with various levels of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feaf04ad0149fa08fb9cb9e14356f8e8
https://doi.org/10.1056/nejmoa1013607