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Autor:
Brennen Arthur Lynch, Andrew K. Udit, Zinaida Polonskaya, Ho Yong Cheong, Kevin Hong, Andrew J. Gale, M. G. Finn, Myles Groner, Jin Kyu Rhee, Michael M. Baksh, William Hollingsworth
Publikováno v:
Biomacromolecules. 18(12)
The anticoagulant activity of heparin administered during medical interventions must be reversed to restore normal clotting, typically by titrating with protamine. Given the acute toxicity associated with protamine, we endeavored to generate safer he