Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Brennan, Decker"'
Autor:
Douglas I. Lin, Julia C. F. Quintanilha, Natalie Danziger, Lixin Lang, Diane Levitan, Cynthia Hayne, Matthew C. Hiemenz, David L. Smith, Lee A. Albacker, Jeffrey Leibowitz, Douglas A. Mata, Brennan Decker, Sotirios Lakis, Nimesh R. Patel, Ryon P. Graf, Julia A. Elvin, Jeffrey S. Ross, Varun Pattani, Richard S. P. Huang, Amy K. Wehn
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract Microsatellite instability high (MSI-H) and mismatch repair deficient (dMMR) tumor status have been demonstrated to predict patient response to immunotherapies. We developed and validated a next-generation sequencing (NGS)-based companion di
Externí odkaz:
https://doaj.org/article/5b1f54d32e854c9184c1c038f53bf3c6
Autor:
Rebekah M. Summey, Erica Gornstein, Brennan Decker, Kali C. Dougherty, Janet S. Rader, Elizabeth Hopp
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Objective The objective of this study was to assess the frequency of potential germline pathogenic variants that may contribute to risk of development of adult granulosa cell tumors (AGCT) given the paucity of germline testing guidelines for
Externí odkaz:
https://doaj.org/article/88b7c71b62fa4d02a01315394a1a0de6
Autor:
Douglas I. Lin, Richard S. P. Huang, Ioannis Ladas, Rachel B. Keller, Nimesh R. Patel, Sotirios Lakis, Brennan Decker, Tyler Janovitz, Douglas A. Mata, Jeffrey S. Ross, Jo-Anne Vergilio, Julia A. Elvin, Roy S. Herbst, Philip C. Mack, Jonathan K. Killian
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundWhile many molecular assays can detect mutations at low tumor purity and variant allele frequencies, complex biomarkers such as tumor mutational burden (TMB), microsatellite instability (MSI), and genomic loss of heterozygosity (gLOH) requi
Externí odkaz:
https://doaj.org/article/f00911dcecc04bac98bd66bb18ec2b34
Autor:
Prashanth Ashok Kumar, Stephen L. Graziano, Natalie Danziger, Dean Pavlick, Eric A. Severson, Shakti H. Ramkissoon, Richard S. P. Huang, Brennan Decker, Jeffrey S. Ross
Publikováno v:
Cancer Medicine, Vol 12, Iss 2, Pp 1157-1166 (2023)
Abstract Introduction New treatment strategies for advanced non‐small‐cell lung carcinoma (NSCLC) include synthetic lethality targets focused on protein arginine methyl transferases such as PRMT5 that exploit the impact of genomic loss of methylt
Externí odkaz:
https://doaj.org/article/f15a3e2f2d5648f0a02913152d789e83
Autor:
Smruthy Sivakumar, Dexter X. Jin, Hanna Tukachinsky, Karthikeyan Murugesan, Kimberly McGregor, Natalie Danziger, Dean Pavlick, Ole Gjoerup, Jeffrey S. Ross, Robert Harmon, Jon Chung, Brennan Decker, Lucas Dennis, Garrett M. Frampton, Luciana Molinero, Steffi Oesterreich, Jeffrey M. Venstrom, Geoffrey R. Oxnard, Priti S. Hegde, Ethan S. Sokol
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Liquid biopsies could be valuable tools to monitor breast cancer progression and evolution. Here, the authors investigate genomic profiling of tissue and liquid biopsies in a large cohort of patients with breast cancer during the course of therapy to
Externí odkaz:
https://doaj.org/article/b3aeff304c474e6c83d5647b3e086870
Publikováno v:
BMJ case reports. 15(10)
A woman presented to medical oncology with almost 4 years of untreated, slowly progressing, triple negative metastatic breast cancer to the lung. About 15 years prior, she was diagnosed with invasive ductal carcinoma of the right breast with ipsilate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2180c52a30116fc807d6bfa7c2ad99f2
https://pubmed.ncbi.nlm.nih.gov/36223973
https://pubmed.ncbi.nlm.nih.gov/36223973
Autor:
Brennan Decker, Richard S.P. Huang, Karthikeyan Murugesan, Douglas A. Mata, Jeffrey S. Ross, Matthew Hiemenz, Gerald Li, James Creeden, Shakti H. Ramkissoon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background The effects of non-amplification short variant (SV) mutations in CD274 (programmed death-ligand 1 (PD-L1)) on PD-L1 protein expression and immune checkpoint inhibitors (ICPIs) therapy are unknown. Here, we present a retrospective analysis
Externí odkaz:
https://doaj.org/article/d546e90affe6487c957e5d5b6692baea
Autor:
Jocelyn Plassais, Jaemin Kim, Brian W. Davis, Danielle M. Karyadi, Andrew N. Hogan, Alex C. Harris, Brennan Decker, Heidi G. Parker, Elaine A. Ostrander
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Being man’s best friend, dogs have been bred and selected for certain morphologic traits and breed-associated behaviours. Here, Plassais et al. analyse 722 canine whole genome sequences including modern breeds, wild canids and village dogs by GWAS
Externí odkaz:
https://doaj.org/article/d9a34c5c4ed34c34b2f9185811d9cf58
Autor:
Andrea Necchi, Philippe E Spiess, Marco Bandini, Giuseppe Basile, Petros Grivas, Gennady Bratslavsky, Joseph Jacob, Natalie Danziger, Douglas Lin, Brennan Decker, Ethan S Sokol, Richard S P Huang, Sanjay B Kulkarni, Jeffrey S Ross
Publikováno v:
The Oncologist. 27:1016-1024
Background Advanced pelvic squamous cell carcinoma (pSCC) is a broad category of cancers affecting different pelvic organs and usually featuring unfavorable clinical outcomes. Thus, we aimed to assess genomic differences among pSCC cases and learn wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da188f99fca4b191d1a7b16da83c739
https://doi.org/10.1093/oncolo/oyac144
https://doi.org/10.1093/oncolo/oyac144
Autor:
Elaine A. Ostrander, Deborah W. Knapp, Elizabeth A. McNiel, Patty L. Bonney, José A. Ramos-Vara, Brian W. Davis, Eric Karlins, Erika M. Kwon, Deepika Dhawan, Heidi G. Parker, Brennan Decker
Supplementary Table 1. This is a table of all mutations found the four InvTCC tumors, there positions, and genotype quality scores.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4679ae05dd244bd8a97b133ae7233d
https://doi.org/10.1158/1541-7786.22515192.v1
https://doi.org/10.1158/1541-7786.22515192.v1
