Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Brenna J. C. Walsh"'
Autor:
Yifan Zhang, Giovanni Gonzalez-Gutierrez, Katherine A. Legg, Brenna J. C. Walsh, Cristian M. Pis Diez, Katherine A. Edmonds, David P. Giedroc
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The extent to which human bacterial pathogens broadly utilize ergothioneine as an antioxidant is unknown. Here, authors describe the discovery of a specific transporter for ergothioneine in a respiratory pathogen that is highly conserved among Firmic
Externí odkaz:
https://doaj.org/article/020e1d9700b54130b84870a80838af9c
Autor:
Brenna J. C. Walsh, Sofia Soares Costa, Katherine A. Edmonds, Jonathan C. Trinidad, Federico M. Issoglio, José A. Brito, David P. Giedroc
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1607 (2022)
Hydrogen sulfide (H2S) is implicated as a cytoprotective agent that bacteria employ in response to host-induced stressors, such as oxidative stress and antibiotics. The physiological benefits often attributed to H2S, however, are likely a result of d
Externí odkaz:
https://doaj.org/article/b80dede8359641e39486f883ee6e0b87
Autor:
Brenna J. C. Walsh, Jiefei Wang, Katherine A. Edmonds, Lauren D. Palmer, Yixiang Zhang, Jonathan C. Trinidad, Eric P. Skaar, David P. Giedroc
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Acinetobacter baumannii is an opportunistic nosocomial pathogen that is the causative agent of several serious infections in humans, including pneumonia, sepsis, and wound and burn infections. A. baumannii is also capable of forming proteina
Externí odkaz:
https://doaj.org/article/9c05a8f948d04b15b84e77a4280b07b8
Autor:
Brenna J. C. Walsh, David P. Giedroc
Publikováno v:
Journal of Biological Chemistry. 295:13150-13168
Bacterial pathogens that cause invasive disease in the vertebrate host must adapt to host efforts to cripple their viability. Major host insults are reactive oxygen and reactive nitrogen species as well as cellular stress induced by antibiotics. Hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67bb0a6e175a3eb0b1ce054ed73dbfb8
https://doi.org/10.1074/jbc.rev120.011304
https://doi.org/10.1074/jbc.rev120.011304
Autor:
Brenna J. C. Walsh, David P. Giedroc
Publikováno v:
BIO-PROTOCOL. 11
Hydrogen sulfide (H2S) is emerging as an important modulator in bacterial cytoprotection against the host immune response in infected animals, which may well be attributed to downstream highly oxidized sulfur species, termed reactive sulfur species (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f565843208388833d6dfbc64746baf0
https://doi.org/10.21769/bioprotoc.4000
https://doi.org/10.21769/bioprotoc.4000
Autor:
Katherine A. Edmonds, Brenna J. C. Walsh, Yixiang Zhang, Lauren D. Palmer, Jonathan C. Trinidad, Jiefei Wang, David P. Giedroc, Eric P. Skaar
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
mBio, Vol 11, Iss 3, p e01254-20 (2020)
mBio
mBio, Vol 11, Iss 3, p e01254-20 (2020)
mBio
Although hydrogen sulfide (H2S) has long been known as a respiratory poison, recent reports in numerous bacterial pathogens reveal that H2S and more downstream oxidized forms of sulfur collectedly termed reactive sulfur species (RSS) function as anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1159ec7491711fe547b201debfe702db
https://doi.org/10.1128/mbio.01254-20
https://doi.org/10.1128/mbio.01254-20
Autor:
Brenna J C, Walsh, David P, Giedroc
Publikováno v:
J Biol Chem
Bacterial pathogens that cause invasive disease in the vertebrate host must adapt to host efforts to cripple their viability. Major host insults are reactive oxygen and reactive nitrogen species as well as cellular stress induced by antibiotics. Hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be062569b59b9627b6b0345a929a2dc0
https://pubmed.ncbi.nlm.nih.gov/32699012
https://pubmed.ncbi.nlm.nih.gov/32699012
Autor:
Brenna J. C. Walsh, Yifan Zhang, Giovanni Gonzalez-Gutierrez, Christopher M Dietrich, Daiana A. Capdevila, David P. Giedroc
Publikováno v:
Nat Chem Biol
Cysteine thiol-based transcriptional regulators orchestrate the coordinated regulation of redox homeostasis and other cellular processes by 'sensing' or detecting a specific redox-active molecule, which in turn activates the transcription of a specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b376dcc190679664e68767a20c99b461
https://pubmed.ncbi.nlm.nih.gov/33106663
https://pubmed.ncbi.nlm.nih.gov/33106663
Hydrogen sulfide (H2S) was once recognized exclusively as toxic molecule that inhibits respiration, but is now considered a bona fide signaling molecule within and between cells, particularly in vertebrates and in man. An understanding of the underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05c7b13ef1682e62b0b67774f4ff7d0a
https://doi.org/10.1016/b978-0-12-409547-2.14699-2
https://doi.org/10.1016/b978-0-12-409547-2.14699-2
Autor:
Hui Peng, Scott J. Hultgren, Yixiang Zhang, Ana L. Flores-Mireles, David P. Giedroc, Yifan Zhang, Brenna J. C. Walsh, Jiangchuan Shen, Jonathan C. Trinidad
Recent studies of hydrogen sulfide (H(2)S) signaling implicate low molecular weight (LMW) thiol persulfides and other reactive sulfur species (RSS) as signaling effectors. Here, we show that a CstR protein from the human pathogen Enterococcus faecali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f97e072b9e71c8aa84cacb0eb5d837
https://europepmc.org/articles/PMC6088750/
https://europepmc.org/articles/PMC6088750/