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pro vyhledávání: '"Brenna Baccaro"'
Autor:
Takahisa Nakamura, Ryan C. Kunz, Cai Zhang, Taishi Kimura, Celvie L. Yuan, Brenna Baccaro, Yuka Namiki, Steven P. Gygi, Gökhan S. Hotamisligil
Publikováno v:
Cell Reports, Vol 11, Iss 2, Pp 295-307 (2015)
Aberrant stress and inflammatory responses are key factors in the pathogenesis of obesity and metabolic dysfunction, and the double-stranded RNA-dependent kinase (PKR) has been proposed to play an important role in integrating these pathways. Here, w
Externí odkaz:
https://doaj.org/article/317f8e3d842c4ff381a6c698c808cbdc
Autor:
Yuka Namiki, Taishi Kimura, Ryan C. Kunz, Gökhan S. Hotamisligil, Cai Zhang, Takahisa Nakamura, Steven P. Gygi, Celvie L. Yuan, Brenna Baccaro
Publikováno v:
Cell Reports, Vol 11, Iss 2, Pp 295-307 (2015)
SummaryAberrant stress and inflammatory responses are key factors in the pathogenesis of obesity and metabolic dysfunction, and the double-stranded RNA-dependent kinase (PKR) has been proposed to play an important role in integrating these pathways.
Autor:
Brenna Baccaro, Alessandro Arduini, Takahisa Nakamura, Masato Furuhashi, Gökhan S. Hotamisligil
Publikováno v:
Diabetes. 63(2)
Obesity and metabolic diseases appear as clusters, often featuring high risk for insulin resistance and type 2 diabetes, and constitute a major global health problem with limited treatment options. Previous studies have shown that double-stranded RNA