Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Brenna A. Y. Stevens"'
Autor:
Darrick L. Yu, Laura P. van Lieshout, Brenna A. Y. Stevens, Kelsie J. (Jagt) Near, Jenny K. Stodola, Kevin J. Stinson, Durda Slavic, Sarah K. Wootton
Publikováno v:
Viruses, Vol 16, Iss 1, p 57 (2023)
Adeno-associated virus (AAV) vectors are among the most widely used delivery vehicles for in vivo gene therapy as they mediate robust and sustained transgene expression with limited toxicity. However, a significant impediment to the broad clinical su
Externí odkaz:
https://doaj.org/article/03d782a89b9b4b69b161f7c5f155a7d8
Autor:
Ashley A. Stegelmeier, Lisa A. Santry, Matthew M. Guilleman, Kathy Matuszewska, Jessica A. Minott, Jacob G. E. Yates, Brenna A. Y. Stevens, Sylvia P. Thomas, Sierra Vanderkamp, Kiersten Hanada, Yanlong Pei, Amira D. Rghei, Jacob P. van Vloten, Madison Pereira, Brad Thompson, Pierre P. Major, James J. Petrik, Byram W. Bridle, Sarah K. Wootton
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 362 (2022)
Epithelial ovarian cancer is the deadliest gynecological malignancy. The lack of effective treatments highlights the need for novel therapeutic interventions. The aim of this study was to investigate whether sustained adeno-associated virus (AAV) vec
Externí odkaz:
https://doaj.org/article/b7a933055d294583b0ee729eeada2323
Autor:
Amira D. Rghei, Laura P. van Lieshout, Benjamin M. McLeod, Yanlong Pei, Jordyn A. Lopes, Nicole Zielinska, Enzo M. Baracuhy, Brenna A. Y. Stevens, Sylvia P. Thomas, Jacob G. E. Yates, Bryce M. Warner, Darwyn Kobasa, Hugues Fausther-Bovendo, Gary P. Kobinger, Khalil Karimi, Brad Thompson, Byram W. Bridle, Leonardo Susta, Sarah K. Wootton
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1186 (2021)
Adeno-associated virus (AAV) vector mediated expression of therapeutic monoclonal antibodies is an alternative strategy to traditional vaccination to generate immunity in immunosuppressed or immunosenescent individuals. In this study, we vectorized a
Externí odkaz:
https://doaj.org/article/f323e697c3344c79998e1eb3bd389d59
Autor:
Brad Thompson, Brenna A Y Stevens, Amira D Rghei, Laura P. van Lieshout, Sarah K. Wootton, Matthew M. Guilleman, Lisa A. Santry, Yanlong Pei
Publikováno v:
Gene Therapy. 30:455-462
Clostridium difficile is the leading cause of antibiotic-associated nosocomial diarrhea in the developed world. When the host-associated colon microbiome is disrupted by the ingestion of antibiotics, C. difficile spores can germinate, resulting in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3457c77a30fa70e708256b1325bb7a10
https://doi.org/10.1038/s41434-021-00236-y
https://doi.org/10.1038/s41434-021-00236-y
Autor:
Byram W. Bridle, Brenna A Y Stevens, Khalil Karimi, Sylvia P. Thomas, Benjamin M. McLeod, Jacob G. E. Yates, Sarah K. Wootton, Amira D Rghei, Leonardo Susta
Publikováno v:
Journal of Visualized Experiments.
Adeno-associated virus (AAV) vectors are among the most clinically advanced gene therapy vectors, with three AAV gene therapies approved for humans. Clinical advancement of novel applications for AAV involves transitioning from small animal models, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c254b755899582e12aff9bd23859bc
https://doi.org/10.3791/62727-v
https://doi.org/10.3791/62727-v
Autor:
Matthew M, Guilleman, Brenna A Y, Stevens, Laura P, Van Lieshout, Amira D, Rghei, Yanlong, Pei, Lisa A, Santry, Brad, Thompson, Sarah K, Wootton
Publikováno v:
Gene therapy.
Clostridium difficile is the leading cause of antibiotic-associated nosocomial diarrhea in the developed world. When the host-associated colon microbiome is disrupted by the ingestion of antibiotics, C. difficile spores can germinate, resulting in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a92059c5f02cc7b60b9604b0216c7d8
https://pubmed.ncbi.nlm.nih.gov/33608675
https://pubmed.ncbi.nlm.nih.gov/33608675
Autor:
Leonardo Susta, Brenna A Y Stevens, Jordyn A. Lopes, Jacob G. E. Yates, Enzo M. Baracuhy, Sarah K. Wootton, Byram W. Bridle, Darwyn Kobasa, Nicole Zielinska, Laura P. van Lieshout, Khalil Karimi, Benjamin M. McLeod, Gary P. Kobinger, Hugues Fausther-Bovendo, Amira D Rghei, Yanlong Pei, Brad Thompson, Bryce M. Warner, Sylvia P. Thomas
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 1186, p 1186 (2021)
Volume 9
Issue 9
Biomedicines, Vol 9, Iss 1186, p 1186 (2021)
Volume 9
Issue 9
Adeno-associated virus (AAV) vector mediated expression of therapeutic monoclonal antibodies is an alternative strategy to traditional vaccination to generate immunity in immunosuppressed or immunosenescent individuals. In this study, we vectorized a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302ea1ec25d840cf9a0940d2bb76cc06
https://doi.org/10.3390/biomedicines9091186
https://doi.org/10.3390/biomedicines9091186
Autor:
Wang, Lamei1,2 (AUTHOR), Villafuerte Gálvez, Javier A.2 (AUTHOR), Lee, Christina2 (AUTHOR), Wu, Shengru1 (AUTHOR), Kelly, Ciaran P.2 (AUTHOR), Chen, Xinhua2 (AUTHOR) xchen1@bidmc.harvard.edu, Cao, Yangchun1,2 (AUTHOR) caoyangchun@126.com
Publikováno v:
iMeta. Jun2024, Vol. 3 Issue 3, p1-17. 17p.
Autor:
Yu, Darrick L.1 (AUTHOR), van Lieshout, Laura P.1 (AUTHOR), Stevens, Brenna A. Y.1 (AUTHOR), Near, Kelsie J.1 (AUTHOR), Stodola, Jenny K.1 (AUTHOR), Stinson, Kevin J.1 (AUTHOR), Slavic, Durda2 (AUTHOR), Wootton, Sarah K.1 (AUTHOR) kwootton@uoguelph.ca
Publikováno v:
Viruses (1999-4915). Jan2024, Vol. 16 Issue 1, p57. 16p.
Publikováno v:
Vaccine Weekly; 5/31/2024, p1108-1108, 1p