A stereoselective, catalytic strategy for the in-flow synthesis of advanced precursors of rasagiline and tamsulosin

Autor: Brenna, Davide, Pirola, Margherita, Raimondi, Laura, Burke, Anthony J., Benaglia, Maurizio

Publikováno v: In Bioorganic & Medicinal Chemistry 1 December 2017 25(23):6242-6247

A New Class of Low-Loading Catalysts for Highly Enantioselective, Metal-Free Imine Reduction of Wide General Applicability.

Autor: Brenna, Davide¹, Porta, Riccardo¹, Massolo, Elisabetta¹, Raimondi, Laura¹, Benaglia, Maurizio¹ maurizio.benaglia@unimi.it

Publikováno v: ChemCatChem. 3/20/2017, Vol. 9 Issue 6, p941-945. 5p.

SUSTAINABLE PREPARATION OF APIS IN BATCH&FLOW MODE, AND IRON CATALYZED TRANSFORMATIONS

Autor: BRENNA, DAVIDE

During my PhD, we focused our attention on the application of the green chemistry principles for the preparation of active pharmaceutical ingredients (API) and, more in general, of highly functionalized chiral molecules, as fine chemicals or building

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::faacf23a97490e78dd21a3ffe1d56c16

Stereoselective Metal-Free Reduction of Chiral Imines in Batch and Flow Mode: A Convenient Strategy for the Synthesis of Chiral Active Pharmaceutical Ingredients

Autor: Brenna, Davide, Benaglia, Maurizio, Porta, Riccardo, Fernandes, Silvia, Burke, Anthony J.

Publikováno v: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
European journal of organic chemistry
2017 (2017): 39–44. doi:10.1002/ejoc.201601268
info:cnr-pdr/source/autori:Brenna, Davide; Benaglia, Maurizio; Porta, Riccardo; Fernandes, Silvia; Burke, Anthony J./titolo:Stereoselective Metal-Free Reduction of Chiral Imines in Batch and Flow Mode: A Convenient Strategy for the Synthesis of Chiral Active Pharmaceutical Ingredients/doi:10.1002%2Fejoc.201601268/rivista:European journal of organic chemistry (Print)/anno:2017/pagina_da:39/pagina_a:44/intervallo_pagine:39–44/volume:2017

The convenient, metal-free reduction of imines that contain an inexpensive and removable chiral auxiliary allowed for the synthesis of the immediate precursors of chiral active pharmaceutical ingredients (APIs). This protocol was carried out under ba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b13aba2dd9a7b2354befc1b468b5ac07
Wiley Online Library

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