Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Brendon Y. Chua"'
Autor:
Isabelle Jia-Hui Foo, Brendon Y. Chua, E. Bridie Clemens, So Young Chang, Xiaoxiao Jia, Hayley A. McQuilten, Ashley Huey Yiing Yap, Aira F. Cabug, Mitra Ashayeripanah, Hamish E. G. McWilliam, Jose A. Villadangos, Maximilien Evrard, Laura K. Mackay, Linda M. Wakim, John K. Fazakerley, Katherine Kedzierska, Lukasz Kedzierski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Immunity to infectious diseases is predominantly studied by measuring immune responses towards a single pathogen, although co-infections are common. In-depth mechanisms on how co-infections impact anti-viral immunity are lacking, but are hig
Externí odkaz:
https://doaj.org/article/f7573a9c40cb46eebac49bbe854be8df
Autor:
Chimuka Handabile, Marumi Ohno, Toshiki Sekiya, Naoki Nomura, Tomomi Kawakita, Mamiko Kawahara, Masafumi Endo, Tomohiro Nishimura, Minako Okumura, Shinsuke Toba, Michihito Sasaki, Yasuko Orba, Brendon Y. Chua, Louise C. Rowntree, Thi H. O. Nguyen, Masashi Shingai, Akihiko Sato, Hirofumi Sawa, Kazumasa Ogasawara, Katherine Kedzierska, Hiroshi Kida
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Due to the synchronous circulation of seasonal influenza viruses and severe acute respiratory coronavirus 2 (SARS-CoV-2) which causes coronavirus disease 2019 (COVID-19), there is need for routine vaccination for both COVID-19 and influenza
Externí odkaz:
https://doaj.org/article/9e57e6f1fec94c65b545be1fe49b8390
Autor:
Thi H. O. Nguyen, Chhay Lim, Masa Lasica, Ashley Whitechurch, Surekha Tennakoon, Natalie R. Saunders, Lilith F. Allen, Louise C. Rowntree, Brendon Y. Chua, Lukasz Kedzierski, Hyon‐Xhi Tan, Adam K. Wheatley, Stephen J. Kent, Theo Karapanagiotidis, Suellen Nicholson, Deborah A. Williamson, Monica A. Slavin, Constantine S. Tam, Katherine Kedzierska, Benjamin W. Teh
Publikováno v:
eJHaem, Vol 4, Iss 1, Pp 216-220 (2023)
Abstract Zanubrutinib‐treated and treatment‐naïve patients with chronic lymphocytic leukaemia (CLL) or Waldenstrom's macroglobulinaemia were recruited in this prospective study to comprehensively profile humoral and cellular immune responses to
Externí odkaz:
https://doaj.org/article/745a4564cb6c465c9f3c734f9e73a326
Autor:
Jennifer R. Habel, Brendon Y. Chua, Lukasz Kedzierski, Kevin J. Selva, Timon Damelang, Ebene R. Haycroft, Thi H.O. Nguyen, Hui-Fern Koay, Suellen Nicholson, Hayley A. McQuilten, Xiaoxiao Jia, Lilith F. Allen, Luca Hensen, Wuji Zhang, Carolien E. van de Sandt, Jessica A. Neil, Katherine Pragastis, Jillian S.Y. Lau, Jaycee Jumarang, E. Kaitlynn Allen, Fatima Amanant, Florian Krammer, Kathleen M. Wragg, Jennifer A. Juno, Adam K. Wheatley, Hyon-Xhi Tan, Gabrielle Pell, Susan Walker, Jennifer Audsley, Arnold Reynaldi, Irani Thevarajan, Justin T. Denholm, Kanta Subbarao, Miles P. Davenport, P. Mark Hogarth, Dale I. Godfrey, Allen C. Cheng, Steven Y.C. Tong, Katherine Bond, Deborah A. Williamson, James H. McMahon, Paul G. Thomas, Pia S. Pannaraj, Fiona James, Natasha E. Holmes, Olivia C. Smibert, Jason A. Trubiano, Claire L. Gordon, Amy W. Chung, Clare L. Whitehead, Stephen J. Kent, Martha Lappas, Louise C. Rowntree, Katherine Kedzierska
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Pregnancy poses a greater risk for severe COVID-19; however, underlying immunological changes associated with SARS-CoV-2 during pregnancy are poorly understood. We defined immune responses to SARS-CoV-2 in unvaccinated pregnant and nonpregnant women
Externí odkaz:
https://doaj.org/article/5baf2d86cad54efcaef6a7913823280a
Autor:
Wuji Zhang, Brendon Y. Chua, Kevin J. Selva, Lukasz Kedzierski, Thomas M. Ashhurst, Ebene R. Haycroft, Suzanne K. Shoffner-Beck, Luca Hensen, David F. Boyd, Fiona James, Effie Mouhtouris, Jason C. Kwong, Kyra Y. L. Chua, George Drewett, Ana Copaescu, Julie E. Dobson, Louise C. Rowntree, Jennifer R. Habel, Lilith F. Allen, Hui-Fern Koay, Jessica A. Neil, Matthew J. Gartner, Christina Y. Lee, Patiyan Andersson, Sadid F. Khan, Luke Blakeway, Jessica Wisniewski, James H. McMahon, Erica E. Vine, Anthony L. Cunningham, Jennifer Audsley, Irani Thevarajan, Torsten Seemann, Norelle L. Sherry, Fatima Amanat, Florian Krammer, Sarah L. Londrigan, Linda M. Wakim, Nicholas J. C. King, Dale I. Godfrey, Laura K. Mackay, Paul G. Thomas, Suellen Nicholson, Kelly B. Arnold, Amy W. Chung, Natasha E. Holmes, Olivia C. Smibert, Jason A. Trubiano, Claire L. Gordon, Thi H. O. Nguyen, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The immune response to SARS-CoV-2 infection is variable but has been linked to prognosis and the development of severe immunopathology. Here the authors assess a range of immune parameters in both peripheral blood and respiratory samples, providing a
Externí odkaz:
https://doaj.org/article/3dbf74c705f948919beba2c6dc7dada4
Autor:
Luca Hensen, Patricia T. Illing, E. Bridie Clemens, Thi H. O. Nguyen, Marios Koutsakos, Carolien E. van de Sandt, Nicole A. Mifsud, Andrea T. Nguyen, Christopher Szeto, Brendon Y. Chua, Hanim Halim, Simone Rizzetto, Fabio Luciani, Liyen Loh, Emma J. Grant, Phillipa M. Saunders, Andrew G. Brooks, Steve Rockman, Tom C. Kotsimbos, Allen C. Cheng, Michael Richards, Glen P. Westall, Linda M. Wakim, Thomas Loudovaris, Stuart I. Mannering, Michael Elliott, Stuart G. Tangye, David C. Jackson, Katie L. Flanagan, Jamie Rossjohn, Stephanie Gras, Jane Davies, Adrian Miller, Steven Y. C. Tong, Anthony W. Purcell, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The immunology of Indigenous populations is generally understudied outside the context of diseases that are prevalent in these communities. Here the authors identify prevalence of influenza CD8+ T cell epitopes in an Indigenous Australian population
Externí odkaz:
https://doaj.org/article/a3a6a4c017e544c7b83819f5cde0c3d5
Systems serology detects functionally distinct coronavirus antibody features in children and elderly
Autor:
Kevin J. Selva, Carolien E. van de Sandt, Melissa M. Lemke, Christina Y. Lee, Suzanne K. Shoffner, Brendon Y. Chua, Samantha K. Davis, Thi H. O. Nguyen, Louise C. Rowntree, Luca Hensen, Marios Koutsakos, Chinn Yi Wong, Francesca Mordant, David C. Jackson, Katie L. Flanagan, Jane Crowe, Shidan Tosif, Melanie R. Neeland, Philip Sutton, Paul V. Licciardi, Nigel W. Crawford, Allen C. Cheng, Denise L. Doolan, Fatima Amanat, Florian Krammer, Keith Chappell, Naphak Modhiran, Daniel Watterson, Paul Young, Wen Shi Lee, Bruce D. Wines, P. Mark Hogarth, Robyn Esterbauer, Hannah G. Kelly, Hyon-Xhi Tan, Jennifer A. Juno, Adam K. Wheatley, Stephen J. Kent, Kelly B. Arnold, Katherine Kedzierska, Amy W. Chung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Antibody responses to SARS-CoV-2 are critical in the immune response to infection, but the potential cross-reactivity to other human corona viruses is poorly appreciated. Here the authors apply a systems based approach to characterise the antibody re
Externí odkaz:
https://doaj.org/article/b3735969bc2442d3bede1a835ba02866
Autor:
Georgia Deliyannis, Chinn Yi Wong, Hayley A. McQuilten, Annabell Bachem, Michele Clarke, Xiaoxiao Jia, Kylie Horrocks, Weiguang Zeng, Jason Girkin, Nichollas E. Scott, Sarah L. Londrigan, Patrick C. Reading, Nathan W. Bartlett, Katherine Kedzierska, Lorena E. Brown, Francesca Mercuri, Christophe Demaison, David C. Jackson, Brendon Y. Chua
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
The impact of respiratory virus infections on global health is felt not just during a pandemic, but endemic seasonal infections pose an equal and ongoing risk of severe disease. Moreover, vaccines and antiviral drugs are not always effective or avail
Externí odkaz:
https://doaj.org/article/4dfcfe2f932a406887c4b13f84a6c4e2
Autor:
Pamela C. Proud, Daphne Tsitoura, Robert J. Watson, Brendon Y. Chua, Marilyn J. Aram, Kevin R. Bewley, Breeze E. Cavell, Rebecca Cobb, Stuart Dowall, Susan A. Fotheringham, Catherine M.K. Ho, Vanessa Lucas, Didier Ngabo, Emma Rayner, Kathryn A. Ryan, Gillian S. Slack, Stephen Thomas, Nadina I. Wand, Paul Yeates, Christophe Demaison, Weiguang Zeng, Ian Holmes, David C. Jackson, Nathan W. Bartlett, Francesca Mercuri, Miles W. Carroll
Publikováno v:
EBioMedicine, Vol 63, Iss , Pp 103153- (2021)
Background: The novel human coronavirus SARS-CoV-2 is a major ongoing global threat with huge economic burden. Like all respiratory viruses, SARS-CoV-2 initiates infection in the upper respiratory tract (URT). Infected individuals are often asymptoma
Externí odkaz:
https://doaj.org/article/f31e56098d3d48869b5be4927c46a453
Autor:
Kirstie M. Mangas, Nicholas J. Tobias, Estelle Marion, Jérémie Babonneau, Laurent Marsollier, Jessica L. Porter, Sacha J. Pidot, Chinn Yi Wong, David C. Jackson, Brendon Y. Chua, Timothy P. Stinear
Publikováno v:
PeerJ, Vol 8, p e9659 (2020)
Background Mycobacterium ulcerans is the causative agent of a debilitating skin and soft tissue infection known as Buruli ulcer (BU). There is no vaccine against BU. The purpose of this study was to investigate the vaccine potential of two previously
Externí odkaz:
https://doaj.org/article/4c8689a8cec14b46b2d5f840826abb6a