Výsledky vyhledávání - "Brendon, MacKenzie"

High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection

Autor: Mohamed R. Hamed, Clifford C. Shone, Brendon MacKenzie, K. Ravi Acharya, Tanya Monaghan, Ola H. Negm, Mark H. Wilcox, David P. Humphreys

Publikováno v: Clinical and Experimental Gastroenterology. 10:169-175

Objectives: Despite multiple risk factors and a high rate of colonization for Clostridium difficile, the occurrence of C. difficile infection in patients with cystic fibrosis is rare. The aim of this study was to compare the prevalence of binding C.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::625f4a91fecd62d98364c7bf2bb481e2
https://doi.org/10.2147/ceg.s133939

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High prevalence of subclass-specific binding and neutralizing antibodies against

Autor: Tanya M, Monaghan, Ola H, Negm, Brendon, MacKenzie, Mohamed R, Hamed, Clifford C, Shone, David P, Humphreys, K Ravi, Acharya, Mark H, Wilcox

Publikováno v: Clinical and Experimental Gastroenterology

Objectives Despite multiple risk factors and a high rate of colonization for Clostridium difficile, the occurrence of C. difficile infection in patients with cystic fibrosis is rare. The aim of this study was to compare the prevalence of binding C. d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::84c4c793f602dff972fa915ed1aa7f2a
https://pubmed.ncbi.nlm.nih.gov/28765714

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Protective antibodies against Clostridium difficile are present in intravenous immunoglobulin and are retained in humans following its administration

Autor: Mark Lynch, K. Ravi Acharya, Brendon MacKenzie, O.A.J. Ahmad, Clifford C. Shone, Tanya Monaghan, Ola H. Negm, Mark H. Wilcox, Izabela Marszalowska, Mohamed R. Hamed, David P. Humphreys, Christine E. Loscher

Summary The prevalence of serum antibodies against Clostridium difficile (CD) toxins A and B in healthy populations have prompted interest in evaluating the therapeutic activity of intravenous immunoglobulin (IVIg) in individuals experiencing severe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4123e9a80706dfe0f4a3c2733dca6eca

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The rapid generation of recombinant functional monoclonal antibodies from individual, antigen-specific bone marrow-derived plasma cells isolated using a novel fluorescence-based method

Autor: Daniel John Lightwood, Rebecca J Wootton, Brendon MacKenzie, Welcome Ndlovu, Dominic P White, Alison Clargo, Sophie P. Shaw, Alastair D. G. Lawson, James Snowden, Meryn Griffiths, Michael E. Wright, Joanne E. Compson, Carla R Nowosad, Ashley R Hudson, Victoria O’Dowd, Louise A Cremin, Dale Starkie, Paul Edward Stephens, Laura Ellen Newnham

Publikováno v: mAbs. 6:143-159

Single B cell technologies, which avoid traditional hybridoma fusion and combinatorial display, provide a means to interrogate the naturally-selected antibody repertoire of immunized animals. Many methods enable the sampling of memory B cell subsets,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56308b11fd5cc660cfd935fa796c86df
https://doi.org/10.4161/mabs.27044

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A Mixture of Functionally Oligoclonal Humanized Monoclonal Antibodies That Neutralize Clostridium difficile TcdA and TcdB with High Levels of In Vitro Potency Shows In Vivo Protection in a Hamster Infection Model

Publikováno v: Clinical and Vaccine Immunology. 20:377-390

Clostridium difficile infections are a major cause of antibiotic-associated diarrhea in hospital and care facility patients. In spite of the availability of effective antibiotic treatments, C. difficile infection (CDI) is still a major cause of patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::502a01b494632943b9983cbcfab8a7ed
https://doi.org/10.1128/cvi.00625-12

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High Prevalence of Subclass-Specific Binding and Neutralising Antibodies Against Clostridium Difficile Toxins in Adult Cystic Fibrosis Sera: Possible Mode of Protection Against Symptomatic Clostridium Difficile Infection

Autor: Clifford C. Shone, Ola H. Negm, K. Ravi Acharya, Mark H. Wilcox, David P. Humphreys, Tanya Monaghan, Brendon MacKenzie, Mohamed R. Hamed

Publikováno v: ResearcherID

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83641aee98d4ba8736bb243d35a5850f
https://doi.org/10.1016/s0016-5085(17)31412-9

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