Comparison of two rapid host-response tests for distinguishing bacterial and viral infection in adults with acute respiratory infection.

Autor: Dedeoglu BE; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Tanner AR; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Brendish NJ; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Moyses HE; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Clark TW; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK. Electronic address: T.W.Clark@soton.ac.uk.

Publikováno v: The Journal of infection [J Infect] 2024 Nov 22, pp. 106360. Date of Electronic Publication: 2024 Nov 22.

Clinical Outcomes of Rapid Respiratory Virus Testing in Emergency Departments: A Systematic Review and Meta-Analysis.

Autor: Schober T; Department of Pediatrics, McGill University, Montreal, Quebec, Canada.; Dr von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Munich, Germany., Wong K; Department of Pediatrics, McGill University, Montreal, Quebec, Canada.; Research Institute McGill University Health Centre, Montreal, Quebec, Canada., DeLisle G; Department of Pediatrics, McGill University, Montreal, Quebec, Canada.; Department of Pediatrics, Université de Montréal, Montreal, Quebec, Canada., Caya C; Research Institute McGill University Health Centre, Montreal, Quebec, Canada., Brendish NJ; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, England.; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, England.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, England., Clark TW; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, England.; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, England.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, England., Dendukuri N; Research Institute McGill University Health Centre, Montreal, Quebec, Canada., Doan Q; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada., Fontela PS; Department of Pediatrics, McGill University, Montreal, Quebec, Canada.; Research Institute McGill University Health Centre, Montreal, Quebec, Canada.; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada., Gore GC; Schulich Library of Physical Sciences, Life Sciences, and Engineering, McGill University, Montreal, Quebec, Canada., Li P; Department of Pediatrics, McGill University, Montreal, Quebec, Canada.; Research Institute McGill University Health Centre, Montreal, Quebec, Canada.; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada., McGeer AJ; Department of Microbiology, Sinai Health System, Toronto, Ontario, Canada., Noël KC; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada., Robinson JL; Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada., Suarthana E; Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada.; Health Technology Assessment Unit, McGill University Health Centre, Montreal, Quebec, Canada., Papenburg J; Department of Pediatrics, McGill University, Montreal, Quebec, Canada.; Research Institute McGill University Health Centre, Montreal, Quebec, Canada.; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.; Division of Microbiology, Department of Clinical Laboratory Medicine, McGill University Health Centre, Montreal, Quebec, Canada.

Publikováno v: JAMA internal medicine [JAMA Intern Med] 2024 May 01; Vol. 184 (5), pp. 528-536.

Clinical impact of syndromic molecular point-of-care testing for gastrointestinal pathogens in adults hospitalised with suspected gastroenteritis (GastroPOC): a pragmatic, open-label, randomised controlled trial.

Autor: Brendish NJ; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; NIHR Southampton Biomedical Research Centre and Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Electronic address: n.brendish@soton.ac.uk., Beard KR; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; NIHR Southampton Biomedical Research Centre and Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Malachira AK; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Tanner AR; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Sanga-Nyirongo L; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Gwiggner M; Department of Gastroenterology, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Cummings JRF; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; NIHR Southampton Biomedical Research Centre and Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Department of Gastroenterology, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Moyses HE; NIHR Southampton Biomedical Research Centre and Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK., Clark TW; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; NIHR Southampton Biomedical Research Centre and Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Department of Infection, University Hospital Southampton NHS Foundation Trust, Southampton, UK; University Hospital Southampton NHS Foundation Trust, Southampton, UK.

Publikováno v: The Lancet. Infectious diseases [Lancet Infect Dis] 2023 Aug; Vol. 23 (8), pp. 945-955. Date of Electronic Publication: 2023 Apr 25.

FebriDx host response point-of-care testing improves patient triage for coronavirus disease 2019 (COVID-19) in the emergency department - ADDENDUM.

Autor: Mansbridge CT, Tanner AR, Beard KR, Borca F, Phan HTT, Brendish NJ, Poole S, Hill C, Kiuber M, Crouch R, Waddington D, Clark TW

Publikováno v: Infection control and hospital epidemiology [Infect Control Hosp Epidemiol] 2022 Aug; Vol. 43 (8), pp. 1099. Date of Electronic Publication: 2022 Apr 11.

Evaluating the Immune Response in Treatment-Naive Hospitalised Patients With Influenza and COVID-19.

Autor: Legebeke J; School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service (NHS) Foundation Trust, Southampton, United Kingdom., Lord J; School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Penrice-Randal R; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Vallejo AF; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Poole S; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service (NHS) Foundation Trust, Southampton, United Kingdom.; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Brendish NJ; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service (NHS) Foundation Trust, Southampton, United Kingdom.; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Dong X; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Hartley C; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom., Holloway JW; School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service (NHS) Foundation Trust, Southampton, United Kingdom., Lucas JS; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service (NHS) Foundation Trust, Southampton, United Kingdom.; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Williams AP; Cancer Sciences Division, Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom., Wheway G; School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Strazzeri F; TopMD Precision Medicine Ltd, Southampton, United Kingdom., Gardner A; TopMD Precision Medicine Ltd, Southampton, United Kingdom., Schofield JPR; TopMD Precision Medicine Ltd, Southampton, United Kingdom., Skipp PJ; TopMD Precision Medicine Ltd, Southampton, United Kingdom.; Centre for Proteomic Research, School of Biological Sciences, University of Southampton, Southampton, United Kingdom., Hiscox JA; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, United Kingdom.; ASTAR Infectious Diseases Laboratories (ASTAR ID Labs), Agency for Science, Technology and Research (ASTAR) Singapore, Singapore, Singapore., Polak ME; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; Institute for Life Sciences, University of Southampton, Southampton, United Kingdom., Clark TW; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service (NHS) Foundation Trust, Southampton, United Kingdom.; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Baralle D; School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service (NHS) Foundation Trust, Southampton, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 May 19; Vol. 13, pp. 853265. Date of Electronic Publication: 2022 May 19 (Print Publication: 2022).