Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Brendan M. Walker"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 5 (2012)
Alcoholism is a chronic relapsing disorder characterized by continued alcohol use despite numerous adverse consequences. Alcohol has been shown to interact with numerous neurotransmitter systems to exert its pharmacological effects. The endogenous op
Externí odkaz:
https://doaj.org/article/f164e472e8a147ed9a5093a7621af325
Autor:
Gaetan Lepreux, Grace E. Shinn, Gengze Wei, Azra Suko, George Concepcion, Sunil Sirohi, Bok Soon Go, Michael R. Bruchas, Brendan M. Walker
Publikováno v:
Neuropharmacology. 228:109457
Publikováno v:
Addict Biol
Impaired working memory is one symptom contributing to compromised executive function in alcohol use disorder (AUD). Dysregulation of cortical dynorphin (DYN) and κ-opioid receptors (KORs) has been implicated in alcohol dependence-induced impairment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd379df057adaef2179b2cc8cf8ed39
https://europepmc.org/articles/PMC8829053/
https://europepmc.org/articles/PMC8829053/
Autor:
Wim van den Brink, Per Sørensen, Lars Torup, Antoni Gual, Karl Mann, Robert M. Swift, Brendan M. Walker
Publikováno v:
European neuropsychopharmacology. 26(12):1941-1949
Nalmefene, a mu- and delta-opioid receptor (MOR, DOR) antagonist and a partial kappa-opioid receptor (KOR) agonist, is approved in the European Union and other countries for the reduction of alcohol consumption in alcohol dependent patients with a hi
Publikováno v:
Addict Biol
A role for matrix metalloproteinases (MMPs) in plasticity-dependent learning has been established. MMPs degrade the extracellular matrix (ECM) when synaptic reorganization is warranted. Previously, we showed that escalation of alcohol self-administra
There is an important emerging role for the endogenous opioid dynorphin (DYN) and the kappa-opioid receptor (KOR) in the treatment of alcohol dependence. Evidence suggests that the DYN/KOR system in the bed nucleus of the stria terminalis (BNST) cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c06b062dd77b232c238fc963106cf3
https://europepmc.org/articles/PMC6232846/
https://europepmc.org/articles/PMC6232846/
Autor:
Jose A. Morón, Ream Al-Hasani, Lucía Hipólito, Shiwei Liu, Nicolas Massaly, Kooresh I. Shoghi, Brendan M. Walker, Robert W. Gereau, Adrianne R. Wilson-Poe, Sunil Sirohi, Amanda Klaas, Hye Jean Yoon, Tamara Markovic, Bryan A. Copits, Michael R. Bruchas, Marie C. Walicki, Dionnet L. Bhatti, Jordan G. McCall, Rachael L. Neve, Catherine M. Cahill
Publikováno v:
Neuron
Negative affective states affect quality of life for patients suffering from pain. These maladaptive emotional states can lead to involuntary opioid overdose and many neuropsychiatric comorbidities. Uncovering the mechanisms responsible for pain-indu
Autor:
Jessica L Kissler, Brendan M. Walker
Publikováno v:
Neuropsychopharmacology. 41:560-567
Chronic intermittent alcohol vapor exposure leads to increased dynorphin (DYN) A-like peptide expression and heightened kappa-opioid receptor (KOR) signaling in the central nucleus of the amygdala (CeA) and these neuroadaptive responses differentiate
Autor:
Brendan M. Walker
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 42(12)
Autor:
Marianne Markowski, Brendan M Walker
Publikováno v:
EVA
This demonstration session presents the artistic and experimental explorations of using VR technology and a motion simulator to allow older people to experience the thrill of roller coasters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696e82c32670352fda94f6531bf35019