Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Brendan M. Byrne"'
Publikováno v:
Genes, Vol 14, Iss 12, p 2205 (2023)
Cells respond to DNA double-strand breaks by initiating DSB repair and ensuring a cell cycle checkpoint. The primary responder to DSB repair is non-homologous end joining, which is an error-prone repair pathway. However, when DSBs are generated after
Externí odkaz:
https://doaj.org/article/188dc2aecbef415b832d4f18f883ed9e
Autor:
Gregory G. Oakley, Brendan M. Byrne
Publikováno v:
Seminars in Cell & Developmental Biology. 86:112-120
The eukaryotic ssDNA-binding protein, Replication protein A (RPA), was first discovered almost three decades ago. Since then, much progress has been made to elucidate the critical roles for RPA in DNA metabolic pathways that help promote genomic stab
Autor:
Peter J. Giannini, Kelly Treude, Russell B. Smith, Shengqin Liu, Dominick J. DiMaio, Jeff Rector, Sasha Kapil, Brendan M. Byrne, Phyllis M. Kumm, Gregory G. Oakley, Lynette M. Smith, Jason G. Glanzer
Publikováno v:
Oncotarget
// Jeff Rector 1 , Sasha Kapil 2 , Kelly J Treude 2 , Phyllis Kumm 1 , Jason G. Glanzer 1 , Brendan M. Byrne 1 , Shengqin Liu 1 , Lynette M Smith 3 , Dominick J DiMaio 4 , Peter Giannini 1 , Russell B Smith 2 , Greg G. Oakley 1, 5 1 Department of Ora
Autor:
Joshua D. Frank, Brendan M. Byrne, Jason G. Glanzer, Ben J. James, Aaron M. McCoy, Greg G. Oakley
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:5388-5392
Ebola virus continues to be problematic as sporadic outbreaks in Africa continue to arise, and as terrorist organizations have considered the virus for bioterrorism use. Several proteins within the virus have been targeted for antiviral chemotherapy,
Autor:
Brendan M. Byrne, Jason G. Glanzer, Greg G. Oakley, Jennifer L. Endres, Shengqin Liu, Kenneth W. Bayles
Publikováno v:
The Journal of antimicrobial chemotherapy. 71(12)
Objectives The increasing threat of drug-resistant bacteria establishes a continuing need for the development of new strategies to fight infection. We examine the inhibition of the essential single-stranded DNA-binding proteins (SSBs) SSBA and SSBB a