Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brendan L. Thoms"'
Publikováno v:
Case Reports in Nephrology and Dialysis, Vol 11, Iss 2, Pp 183-189 (2021)
Antineutrophil cytoplasmic autoantibody (ANCA) vasculitis has occasionally been associated with other systemic glomerulonephritis, such as anti-glomerular basement membrane disease. Here, we report the first clinical case of ANCA-associated crescenti
Externí odkaz:
https://doaj.org/article/c20c13fca8294052abf0304703fa2668
Publikováno v:
Case Reports in Nephrology and Dialysis
Case Reports in Nephrology and Dialysis, Vol 11, Iss 2, Pp 183-189 (2021)
Case Reports in Nephrology and Dialysis, Vol 11, Iss 2, Pp 183-189 (2021)
Antineutrophil cytoplasmic autoantibody (ANCA) vasculitis has occasionally been associated with other systemic glomerulonephritis, such as anti-glomerular basement membrane disease. Here, we report the first clinical case of ANCA-associated crescenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf9ef4fd59bbda122fb4f9f6a23ef97
http://europepmc.org/articles/PMC8299401
http://europepmc.org/articles/PMC8299401
Publikováno v:
Rheumatology. 54:1528-1530
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7edc9d70724bca3c42482cd4ce175da5
https://doi.org/10.1093/rheumatology/kev120
https://doi.org/10.1093/rheumatology/kev120
Publikováno v:
Clinical Science. 125:461-470
PTHrP (parathyroid hormone-related protein) is crucial for normal cartilage development and long bone growth and acts to delay chondrocyte hypertrophy and terminal differentiation in the growth plate. After growth plate closure adult HACs (human arti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05aee617945e4155bd38d9eec2275b7
https://doi.org/10.1042/cs20120610
https://doi.org/10.1042/cs20120610
Publikováno v:
Arthritis Research & Therapy
In a chronically hypoxic tissue such as cartilage, adaptations to hypoxia do not merely include cell survival responses, but also promotion of its specific function. This review will focus on describing such hypoxia-mediated chondrocyte function, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f37a66dbb26173978344ea5b68fddfb
https://ora.ox.ac.uk/objects/uuid:83c48a8a-e7e0-4b75-a89b-12b06a5f29ef
https://ora.ox.ac.uk/objects/uuid:83c48a8a-e7e0-4b75-a89b-12b06a5f29ef
Publikováno v:
Arthritis and rheumatism. 65(5)
Objective To determine the effects of hypoxia on both anabolic and catabolic pathways of metabolism in human articular cartilage and to elucidate the roles played by hypoxia-inducible factors (HIFs) in these responses. Methods Normal human articular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d78ad0a87c1bb4a1bffeab5fa582af
https://pubmed.ncbi.nlm.nih.gov/23334958
https://pubmed.ncbi.nlm.nih.gov/23334958
Publikováno v:
The Journal of biological chemistry. 285(27)
Human articular cartilage is an avascular tissue, and therefore it functions in a hypoxic environment. Cartilage cells, the chondrocytes, have adapted to this and actually use hypoxia to drive tissue-specific functions. We have previously shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab804bdbc57ce5e907ef50d642836518
http://ora.ox.ac.uk/objects/uuid:4d35884f-93c4-4107-8e70-3fdc8202da7c
http://ora.ox.ac.uk/objects/uuid:4d35884f-93c4-4107-8e70-3fdc8202da7c