Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Brendan Kohrn"'
Autor:
Scott R Kennedy, Eric M Schultz, Thomas M Chappell, Brendan Kohrn, Gary M Knowels, Alan J Herr
Publikováno v:
PLoS Genetics, Vol 11, Iss 4, p e1005151 (2015)
Mutator phenotypes accelerate the evolutionary process of neoplastic transformation. Historically, the measurement of mutation rates has relied on scoring the occurrence of rare mutations in target genes in large populations of cells. Averaging mutat
Externí odkaz:
https://doaj.org/article/33c7657dbb654d398dffdedbb88c520d
Autor:
Rosa Ana Risques, Miguel A. Peinado, William M. Grady, Victor Moreno, Thierry Soussi, Xianyong Gui, Ting Wang, Ming Yu, Kelly Carter, Jeanne Fredrickson, Brendan Kohrn, Julia Matas
Supplementary Figure from Colorectal Cancer Is Associated with the Presence of Cancer Driver Mutations in Normal Colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37879e9eeda386f14f6fa985690f9767
https://doi.org/10.1158/0008-5472.22430716
https://doi.org/10.1158/0008-5472.22430716
Autor:
Rosa Ana Risques, Miguel A. Peinado, William M. Grady, Victor Moreno, Thierry Soussi, Xianyong Gui, Ting Wang, Ming Yu, Kelly Carter, Jeanne Fredrickson, Brendan Kohrn, Julia Matas
Supplementary Data from Colorectal Cancer Is Associated with the Presence of Cancer Driver Mutations in Normal Colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ace31468bb57bd22b3b5e32a1898721
https://doi.org/10.1158/0008-5472.22430719.v1
https://doi.org/10.1158/0008-5472.22430719.v1
Autor:
Christophe Herman, Catherine Bradley, Alasdair Gordon, Chen Wang, Matthew Cooke, Brendan Kohrn, Scott Kennedy, Olivier Lichtarge, Shannon Ronca
Publikováno v:
Research square.
Both the SARS-CoV-2 virus and its mRNA vaccines depend on RNA polymerases (RNAP)1,2; however, these enzymes are inherently error-prone and can introduce variants into the RNA3. To understand SARS-CoV-2 evolution and vaccine efficacy, it is critical t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f076f1d36dcea163708982e4a4fa67
https://pubmed.ncbi.nlm.nih.gov/35677076
https://pubmed.ncbi.nlm.nih.gov/35677076
Autor:
Julia Matas, Brendan Kohrn, Jeanne Fredrickson, Kelly Carter, Ming Yu, Ting Wang, Xianyong Gui, Thierry Soussi, Victor Moreno, William M. Grady, Miguel A. Peinado, Rosa Ana Risques
Publikováno v:
Cancer Res
Cancer Research
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Cancer Research
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Although somatic mutations in colorectal cancer are well characterized, little is known about the accumulation of cancer mutations in the normal colon before cancer. Here, we have developed and applied an ultrasensitive, single-molecule mutational te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465bcebbcf8d479ea4c8dd36e5c287c2
https://pubmed.ncbi.nlm.nih.gov/35425963
https://pubmed.ncbi.nlm.nih.gov/35425963
Autor:
Talayeh Ghezelayagh, Jeanne Fredrickson, Enna Manhardt, Marc Radke, Brendan Kohrn, Heidi Gray, Renata Urban, Kathryn Pennington, John Liao, Kemi Doll, Elise Simons, Jennifer Burzawa, Barbara Goff, Paul Speiser, Elizabeth Swisher, Rosana Risques, Barbara Norquist
Publikováno v:
Gynecologic Oncology. 164:8-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bcc1fcf0ceadbbb886dea1c184e1bbe
https://doi.org/10.1016/j.ygyno.2021.10.064
https://doi.org/10.1016/j.ygyno.2021.10.064
Autor:
Talayeh Ghezelayagh, Jeanne Fredrickson, Jeffrey Krimmel-Morrison, Brendan Kohrn, Marc Radke, Enna Manhardt, Ronit Katz, Barbara Norquist, Elizabeth Swisher, Rosana Risques
Publikováno v:
Gynecologic Oncology. 166:S125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da17dfdb735da58f9b3d2f2e9594fcc7
https://doi.org/10.1016/s0090-8258(22)01451-2
https://doi.org/10.1016/s0090-8258(22)01451-2
Autor:
Robert A. Beckman, Brendan Kohrn, Kaitlyn Loubet-Senear, Jasmin Dunn, Jacintha OSullivan, Mary Bronner, Lawrence A. Loeb
Publikováno v:
Cancer Research. 79:3770-3770
Human colorectal cancers (CRC) contain numerous positively selected clonal somatic mutations in 10% or more of the cells. In addition, subclonal mutations in a fraction of cells contribute to phenotypic heterogeneity. Several groups have shown either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::028967c624ce294eecc83ac2b01dc593
https://doi.org/10.1158/1538-7445.am2019-3770
https://doi.org/10.1158/1538-7445.am2019-3770