Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Brendan J. Whittle"'
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible enzyme situated downstream of cyclo-oxygenase-2, promoting the excessive PGE2 production in inflammation. Dexamethasone is known to suppress mPGES-1 but the mechanisms regulating mPGES-1
Externí odkaz:
https://doaj.org/article/6357037b3fe54c35ab9b43ad255758e2
Autor:
Jigisha A. Patel, Lei Shen, Susan M. Hall, Chabha Benyahia, Xavier Norel, Robin J. McAnulty, Shahin Moledina, Adam M. Silverstein, Brendan J. Whittle, Lucie H. Clapp
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2372 (2018)
Prostacyclins are extensively used to treat pulmonary arterial hypertension (PAH), a life-threatening disease involving the progressive thickening of small pulmonary arteries. Although these agents are considered to act therapeutically via the prosta
Externí odkaz:
https://doaj.org/article/05cd0d778a5b41459a32e560d4659cb8