C 2 ‐Symmetric Cinchona Alkaloid Derivatives: Versatile Catalysts for the Enantioselective C−C Bond Forming Conjugate Addition of Nucleophiles to Simple α,β‐Unsaturated Acyl Pyrazoles

Autor: Simon P. Curran, Stephen J. Connon, Brendan J. Fallon

Publikováno v: ChemistrySelect. 5:15190-15194

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68d11cdab88e6476161aa8c11c994bce
https://doi.org/10.1002/slct.202004505

Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis

Autor: Sean M. Lynn, Brendan J. Fallon, Simon J. F. Macdonald, Ian B. Campbell, Steven L. Sollis, Panayiotis A. Procopiou, Lee R. Thorp, Anderson Niall Andrew, John Martin Pritchard

Publikováno v: Organic & Biomolecular Chemistry. 14:5992-6009

A diastereoselective synthesis of (S)-3-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl)-4-((R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic acid (1), a potential therapeutic agent for the treatment of Idiopathic Pulmonary Fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd7b9aa34329a6eef11c3dc178d6e1c
https://doi.org/10.1039/c6ob00496b

Hydroboration and Diboration of Internal Alkynes Catalyzed by a Well-Defined Low-Valent Cobalt Catalyst

Autor: Ye Lyu, Muriel Amatore, Laura Ferrand, Marc Petit, Alejandro Rivera-Hernández, Corinne Aubert, Brendan J. Fallon

Publikováno v: Synthesis
Synthesis, 2017, 49 (17), pp.3895--3904. ⟨10.1055/s-0036-1588996⟩
Synthesis: Journal of Synthetic Organic Chemistry
Synthesis: Journal of Synthetic Organic Chemistry, 2017, 49 (17), pp.3895--3904. ⟨10.1055/s-0036-1588996⟩

The use of a simple well-defined low-valent cobalt(I) catalyst [HCo(PMe3)4] capable of performing the regio- and stereoselective hydroboration of internal alkynes is reported. Extension to the diboration of internal alkynes is also related using the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10686b354e7436ef29943cc4dcb50a2d
https://hal.archives-ouvertes.fr/hal-01644384

ChemInform Abstract: C2-Alkylation and Alkenylation of Indoles Catalyzed by a Low-Valent Cobalt Complex in the Absence of Reductant

Autor: Brendan J. Fallon, Muriel Amatore, Corinne Aubert, Marc Petit, Franck Ferreira, Alejandro Perez-Luna, Fabrice Chemla, Etienne Derat

Publikováno v: ChemInform. 47

Herein an extremely versatile, well-defined, low-valent cobalt catalyst [Co(PMe3)4] capable of intermolecular and intramolecular imine-directed C2-alkylation and alkenylation of indoles is reported. The reaction proceeds in the absence of reducing ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d718b7595929c3a22cdd3e89bbc8343
https://doi.org/10.1002/chin.201637100

A well-defined low-valent cobalt catalyst Co(PMe3)4 with dimethylzinc: a simple catalytic approach for the reductive dimerization of benzyl halides

Autor: Vincent Corcé, Franck Ferreira, Muriel Amatore, Alejandro Perez-Luna, Marc Petit, Fabrice Chemla, Corinne Aubert, Brendan J. Fallon

Publikováno v: New J. Chem.
New J. Chem., 2016, 40 (12), pp.9912--9916. ⟨10.1039/C6NJ03265F⟩

International audience; Herein, we report the first catalytic version of a cobalt-catalysed reductive homocoupling of benzyl halides which proceeds with low catalyst loadings (0.5 to 5 mol%). By synthetizing each cobalt intermediate we demonstrate th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b33b7e1ba417f8531713d3a0061cb35
https://hal.archives-ouvertes.fr/hal-01638307