Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Brendan J Tunstall"'
Autor:
Rajtarun Madangopal, Brendan J Tunstall, Lauren E Komer, Sophia J Weber, Jennifer K Hoots, Veronica A Lennon, Jennifer M Bossert, David H Epstein, Yavin Shaham, Bruce T Hope
Publikováno v:
eLife, Vol 8 (2019)
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency (‘incubate’) over time. Animal models of incubation may help develop treatments to prevent relapse, but these models have ubiquitously
Externí odkaz:
https://doaj.org/article/dd1c5cdadf0c42d6a522a5193016f968
Autor:
David C. Yeomans, Leah R. Hanson, Dean S. Carson, Brendan J. Tunstall, Mary R. Lee, Alexander Z. Tzabazis, Daniel Jacobs, William H. Frey
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract There is evidence of the therapeutic potential of intranasal oxytocin for the treatment of pain and various psychiatric disorders, however, there is scant evidence that oxytocin reaches the brain. We quantified the concentration and distribu
Externí odkaz:
https://doaj.org/article/941b748b10d24d72a4c41802e25eb95e
κ-Opioid receptor antagonism reverses heroin withdrawal-induced hyperalgesia in male and female rats
Autor:
Renata C.N. Marchette, Adriana Gregory-Flores, Brendan J. Tunstall, Erika R. Carlson, Shelley N. Jackson, Agnieszka Sulima, Kenner C. Rice, George F. Koob, Leandro F. Vendruscolo
Publikováno v:
Neurobiology of Stress, Vol 14, Iss , Pp 100325- (2021)
Although opioids are potent analgesics, a consequence of chronic opioid use is hyperalgesia during withdrawal, which may contribute to opioid misuse. Dynorphin, the endogenous ligand of κ-opioid receptors (KORs), is upregulated in opioid-dependent r
Externí odkaz:
https://doaj.org/article/4867716d25994c5a87c5fd5a91adeb0c
Publikováno v:
Learning & Behavior. 50:509-523
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9dae2280a6f7bb94cc1b18cf346086b
https://doi.org/10.3758/s13420-022-00512-w
https://doi.org/10.3758/s13420-022-00512-w
Autor:
Grey A. Gage, Marissa A. Muench, Changhoon Jee, David N. Kearns, Hao Chen, Brendan J. Tunstall
Publikováno v:
Neuropharmacology. 235:109564
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0980cd9fc4d6a938d059952e226d8da
https://doi.org/10.1016/j.neuropharm.2023.109564
https://doi.org/10.1016/j.neuropharm.2023.109564
Autor:
Mehdi Farokhnia, Christopher T. Rentsch, Vicky Chuong, M. Adrienne McGinn, Sophie K. Elvig, Eliza A. Douglass, Luis A. Gonzalez, Jenna E. Sanfilippo, Renata C. N. Marchette, Brendan J. Tunstall, David A. Fiellin, George F. Koob, Amy C. Justice, Lorenzo Leggio, Leandro F. Vendruscolo
Publikováno v:
Mol Psychiatry
Evidence suggests that spironolactone, a nonselective mineralocorticoid receptor (MR) antagonist, modulates alcohol seeking and consumption. Therefore, spironolactone may represent a novel pharmacotherapy for alcohol use disorder (AUD). In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b30d20cea46f5800998006f39bd589
https://researchonline.lshtm.ac.uk/id/eprint/4667528/1/Farokhnia_etal_2022_Spironolactone-as-a-potential-new.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4667528/1/Farokhnia_etal_2022_Spironolactone-as-a-potential-new.pdf
Autor:
Olivia R Drake, Bruce T. Hope, Jennifer M. Bossert, Leslie A. Ramsey, Veronica A Lennon, Brendan J. Tunstall, Rajtarun Madangopal, Megan B Brenner, Lauren E Komer, Sophia J Weber, Yavin Shaham
Publikováno v:
Neuropsychopharmacology
Persistent susceptibility to cue-induced relapse is a cardinal feature of addiction. Discriminative stimuli (DSs) are one type of drug-associated cue that signal drug availability (DS+) or unavailability (DS−) and control drug seeking prior to rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553271639e902469e3ee01f897f3b41e
https://doi.org/10.1038/s41386-021-01067-6
https://doi.org/10.1038/s41386-021-01067-6
Publikováno v:
Drug and Alcohol Dependence. 245:109797
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96e9d90741dc3bf5f833bba3a672f830
https://doi.org/10.1016/j.drugalcdep.2023.109797
https://doi.org/10.1016/j.drugalcdep.2023.109797
Autor:
Jillian Helen Broadbear, Brendan J. Tunstall, Kristina Vacy, Ronan Depoortère, David Ralph, Adrian Newman-Tancredi
Publikováno v:
Behav Pharmacol
NLX-101 and F13714 are selective, full efficacy, biased agonists of the 5-HT(1A) receptor. NLX-101 preferentially activates cortical post-synaptic 5-HT(1A) receptors whereas F13714 preferentially activates Raphe nuclei pre-synaptic 5-HT(1A) receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfc4e9f82913f64e1a141aa1acd0228
https://europepmc.org/articles/PMC8589115/
https://europepmc.org/articles/PMC8589115/
Publikováno v:
Frontiers in Psychology, Vol 6 (2015)
The present experiment investigated potential reinstaters of suboptimal economic decision making in rats. Rats were first trained on a version of the rat Gambling Task under conditions designed to promote choice of a suboptimal option that occasional
Externí odkaz:
https://doaj.org/article/fa79895e6d3446a89e4284487182152e